Plagued

Although not the first episode that we recorded we figured it made sense to go live with the most apt disease. It's one with an incredible history, a lot of which you will know but some of which you might not! 

Enjoy!

Theme by Barbarian Hermit

Main Artwork by Dafydd Jones

References

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Barbieri, R. (2020). Yersinia pestis: The natural history of plague. Clinical Microbiology Reviews, 34(1). https://doi.org/10.1128/cmr.00044-19

Britannica. (2023, May 14). Black Death - Cause and outbreak. Britannica. Encyclopedia Britannica. https://www.britannica.com/event/Black-Death/Cause-and-outbreak

Butler, T. (2014). Plague history: Yersin’s discovery of the causative bacterium in 1894 enabled, in the subsequent century, scientific progress in understanding the disease and the development of treatments and vaccines. Clinical Microbiology and Infection, 20(3), 202–209. https://doi.org/10.1111/1469-0691.12540

CDC. (2024, May 15). Signs and symptoms of plague. CDC. Plague. https://www.cdc.gov/plague/signs-symptoms/index.html

Cost-effective treatment for bubonic plague shown to be highly effective and. (2025, August 7). Lshtm. https://www.lshtm.ac.uk/newsevents/news/2025/cost-effective-treatment-bubonic-plague-shown-be-highly-effective

Cox, D. (2024, March 24). How bubonic plague rewired the human immune system. Www.Bbc.Com. https://www.bbc.co.uk/future/article/20240220-bubonic-plague-did-the-black-death-rewire-our-immune-system

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Heckel, J., & Bureau, I. N. (2022, October 27). Tracing the roots of the black death. College of Liberal Arts & Sciences at Illinois. https://las.illinois.edu/news/2022-10-27/tracing-roots-black-death

Ibn Khaldun. (2022). An infallible criterion | Ibn Khaldun. Lapham’s Quarterly. https://www.laphamsquarterly.org/roundtable/infallible-criterion

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Irving, M. (2026, July 22). We may finally have a vaccine against the plague, with two new vaccines showing 100% effectiveness in mice. ScienceAlert. https://www.sciencealert.com/new-plague-vaccines-100-effective-against-the-deadly-disease-in-mice

Justinianic plague was nothing like flu and may have hit England before constantinople. (2021, November 22). University of Cambridge. https://www.cam.ac.uk/research/news/justinianic-plague-was-nothing-like-flu-and-may-have-hit-england-before-constantinople

Lei, C., & Kumar, S. (2022). Yersinia pestis antibiotic resistance: A systematic review. Osong Public Health and Research Perspectives, 13(1), 24–36. https://doi.org/10.24171/j.phrp.2021.0288

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Randremanana, R. V., Raberahona, M., Bourner, J., Rajerison, M., Edwards, T., Randriamparany, R., Fehizoro Razafindratsinana, T., Razananaivo, L. H., Zadonirina, G., Mayouya-Gamana, T., Salam, A. P. A., Mangahasimbola, R. T., Andrianaivoarimanana, V., Pesonel, E., Rakotoarivelo, R. A., Randria, M. J. de D., Horby, P., & Olliaro, P. (2025). Ciprofloxacin versus aminoglycoside–ciprofloxacin for bubonic plague. New England Journal of Medicine, 393(6), 544–555. https://doi.org/10.1056/nejmoa2413772

Spyrou, M. A. (2022). The source of the black death in fourteenth-century Central Eurasia. Nature, 606(7915), 718–724. https://doi.org/10.1038/s41586-022-04800-3

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World Health Organization. (2022, July 7). Plague. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/plague