In this latest OIES podcast James Henderson talks to Adnan Shihab-Eldin and Holger Rogner about their latest paper on the future of nuclear energy, that was co-authored with Robert Budnitz and Charles McCombie. The discussion covers the global outlook for nuclear energy, which has shifted significantly in the last few years from predominantly unfavourable or dismissive views to strongly favourable and optimistic perspectives, in countries all around the world, both developed and developing. This shift is reflected in the growing support for the declaration to triple nuclear capacity by 2050, first endorsed by 21 countries at COP28, and since expanded to include 38 countries. The podcast then looks at a number of important challenges that could delay or hinder nuclear energy's contribution to overall energy and security goals as well as global climate goals. These include economic competitiveness, supply-chain readiness, fuel cycle and waste management issues, regulatory and institutional capacity, and the need to maintain strong safety, security, and safeguards frameworks. These challenges are especially important as new technologies such as small modular reactors (SMRs) and other advanced reactors are deployed. The podcast then examines the major economic, institutional, and technical factors that will shape the future deployment of nuclear power. It reviews the current status of nuclear technologies and programmes, identifies key issues that may influence the pace and scale of nuclear expansion, and highlights areas where further analysis could support policy and investment decisions.