The Bio Report

Predicting the Unpredictable Off-Target Activities of Drugs


Listen Later

One of the reasons for the high cost of drug development is that most drugs fail in clinical development. Even though preclinical testing can provide a good insight into whether a drug hits an intended target, once in the body, drugs can interact with a large number of proteins and have unintended consequences. A-Alpha Bio, a spinout from the University of Washington's Institute for Protein Design and Center for Synthetic Biology, is developing a platform that can measure thousands of protein interactions simultaneously and how drugs affect them. We spoke to David Younger, co-founder and CEO of A-Alpha, about the company’s platform, the bottleneck in drug development it is addressing, and the business model it is pursuing.
...more
View all episodesView all episodes
Download on the App Store

The Bio ReportBy Levine Media Group

  • 3.9
  • 3.9
  • 3.9
  • 3.9
  • 3.9

3.9

37 ratings


More shows like The Bio Report

View all
HBR IdeaCast by Harvard Business Review

HBR IdeaCast

217 Listeners

The McKinsey Podcast by McKinsey & Company

The McKinsey Podcast

387 Listeners

Masters in Business by Bloomberg

Masters in Business

2,177 Listeners

Goldman Sachs Exchanges by Goldman Sachs

Goldman Sachs Exchanges

988 Listeners

The Long Run with Luke Timmerman by Timmerman Report

The Long Run with Luke Timmerman

124 Listeners

The Readout Loud by STAT

The Readout Loud

316 Listeners

Practical AI by Practical AI LLC

Practical AI

189 Listeners

Biotech 2050 Podcast by Biotech 2050

Biotech 2050 Podcast

60 Listeners

Business Of Biotech by Ben Comer

Business Of Biotech

85 Listeners

BioCentury This Week by BioCentury

BioCentury This Week

30 Listeners

Raising Health by Andreessen Horowitz, a16z Bio + Health

Raising Health

143 Listeners

Biotech Hangout by Daphne Zohar, Josh Schimmer, Brad Loncar, Tim Opler & more

Biotech Hangout

10 Listeners

HBR On Strategy by Harvard Business Review

HBR On Strategy

79 Listeners

HBR On Leadership by Harvard Business Review

HBR On Leadership

143 Listeners

Ground Truths by Eric Topol

Ground Truths

46 Listeners