The Tennessee Titans face off with the Indianapolis Colts in a critical AFC South matchup. We break down the key storylines:

• Tony Pollard’s dominance running between the tackles and how the Colts’ front of DeForest Buckner and Kwity Paye could slow him down.
• Jonathan Taylor leading the NFL in rushing and why tackling will be the deciding factor for the Titans defense.
• Colts’ pass rush struggles and whether Cam Ward can take advantage.
• Injury updates: Latu, Tyler Warren, T’Vondre Sweat, and Chavarius Ward.
• Special teams X-factor — how new coordinator Bones Fassel could help Tennessee flip a game that has gone Indy’s way in four straight meetings.

Will the Titans finally break the streak against Indy? Tune in for full analysis, X-factors, and our predictions.

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