Pro-PA Podcast

In this episode, we explore Multiple Myeloma, a malignant plasma cell disorder known for its CRAB criteria—hyperCalcemia, Renal failure, Anemia, and Bone lesions. We'll discuss the classic presentation of back pain, lytic bone lesions, and recurrent infections, as well as hallmark findings like M protein spike, Bence Jones proteins, and Rouleaux formation on blood smear. Tune in to master the essentials for clinical practice and PANCE prep!

#MultipleMyeloma #CRABcriteria #BenceJones #RouleauxFormation #PANCEprep #ProPAPodcast #HEME101

In this high-yield episode, we cover Burkitt Lymphoma, one of the fastest-growing human tumors, often associated with EBV and characterized by its iconic “starry sky” appearance on histology. You'll learn to distinguish between the endemic, sporadic, and immunodeficiency-associated subtypes, recognize key clinical presentations (like jaw or abdominal masses), and master board-relevant facts for the PANCE.

#BurkittLymphoma #StarrySkyAppearance #EBV #HighGradeLymphoma #PANCEprep #ProPAPodcast #HEME101

This episode takes a focused look at Hodgkin Lymphoma, a distinct B-cell malignancy known for its classic Reed-Sternberg cells and predictable pattern of spread. We'll review the hallmark B symptoms, staging systems, and how this condition stands apart from Non-Hodgkin Lymphoma. Plus, we’ll discuss common presentations in young adults and key treatment pearls to help solidify this high-yield topic for the PANCE.

#HodgkinLymphoma #ReedSternberg #Bsymptoms #LymphomaReview #PANCEprep #ProPAPodcast #HEME101

In this episode, we unpack Non-Hodgkin Lymphoma (NHL)—a diverse group of lymphoid malignancies that vary in presentation, progression, and prognosis. We'll break down the most common subtypes, including diffuse large B-cell lymphoma and follicular lymphoma, and highlight key differences from Hodgkin Lymphoma. Expect coverage of risk factors (like immunosuppression and viral associations), clinical features (e.g., painless lymphadenopathy, B symptoms), and diagnostic/treatment strategies.

#NonHodgkinLymphoma #NHL #LymphomaSubtypes #DLBCL #HEME101 #PANCEreview #ProPAPodcast

In this episode, we explore Chronic Myeloid Leukemia (CML)—a myeloproliferative disorder defined by the Philadelphia chromosome and BCR-ABL fusion gene. Learn how this disease progresses through chronic, accelerated, and blast phases, and how to recognize key signs like marked leukocytosis and splenomegaly. We’ll also review first-line treatment with tyrosine kinase inhibitors such as imatinib and when to suspect CML in asymptomatic patients with abnormal labs.

#CML #PhiladelphiaChromosome #BCRABL #TyrosineKinaseInhibitor #HEME101 #PANCEreview #ProPAPodcast

In this high-yield episode, we dive into Acute Myeloid Leukemia (AML)—a rapidly progressive hematologic malignancy seen most often in older adults. We cover hallmark features such as pancytopenia, fatigue, bleeding, and infection, and highlight the classic finding of Auer rods on peripheral smear. You’ll also learn the importance of blasts >20% in the bone marrow and the basics of AML subtypes, including acute promyelocytic leukemia (APL) with its life-threatening DIC risk.

#AML #AcuteMyeloidLeukemia #AuerRods #PANCEprep #PAstudent #HEME101 #ProPAPodcast

In this episode, we explore the basics of Chronic Lymphocytic Leukemia (CLL)—the most common leukemia in adults. We’ll cover typical clinical findings like lymphadenopathy and recurrent infections, the importance of smudge cells on peripheral smear, and diagnostic tools like flow cytometry. Plus, we’ll review Rai staging and treatment considerations based on disease progression and patient symptoms.

#CLL #ChronicLymphocyticLeukemia #PANCEprep #PAstudent #Leukemia #HEME101 #ProPAPodcast

In this episode, we break down the essentials of Acute Lymphoblastic Leukemia (ALL)—the most common childhood cancer. Learn the hallmark clinical features (like bone pain and CNS involvement), diagnostic workup including peripheral smear and bone marrow biopsy, and the high-yield cytogenetic findings (like t(12;21) and Philadelphia chromosome). We also touch on prognosis, treatment phases, and complications to look out for during therapy.

#AcuteLymphoblasticLeukemia #ALL #PANCEprep #PAstudent #Leukemia #HEME101 #ProPAPodcast

In this episode, we walk through the most important Transfusion Reactions you need to know for clinical practice and the PANCE. From acute hemolytic reactions to febrile non-hemolytic, allergic, and TRALI (transfusion-related acute lung injury), we highlight key signs, timing, causes, and treatments. Learn how to quickly recognize and manage each type—and what labs and protocols to follow when they occur.

#TransfusionReactions #TRALI #Hemolysis #PAstudent #PANCEprep #HEME101 #ProPAPodcast

This episode covers Beta Thalassemia, a genetic disorder resulting from mutations in the beta-globin gene, leading to reduced or absent beta-chain production. We break down the differences between Beta Thalassemia Minor and Beta Thalassemia Major (Cooley anemia)—including clinical presentations, target cells on smear, iron overload risk, and electrophoresis findings. A high-yield discussion to help you master this microcytic anemia for the PANCE!

#BetaThalassemia #MicrocyticAnemia #Hemoglobinopathies #PAstudent #PANCEprep #HEME101 #ProPAPodcast