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QUESTIONS
OUTLINE
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Questions:
Outline – Notes:
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Vaccines vs. Treatment
-Treatment vs. Prevention
-Treatment is not curative – examples are HTN, anti-diabetic medications, anti-asthma medications
-New options are antibody serum, gene PCR techniques
-Prevention – examples are vaccines, gene transformations
-Vaccine manufacturing process
-Production technologies – using flu vaccine as an example
-Egg-based
-Cell based
-Recombinant
-https://www.cdc.gov/flu/prevent/how-fluvaccine-made.htm
-Coronavirus vaccine
-Exploratory stage (2-4yrs)
-Pre-clinical stage – animal tests 1-2 yrs.
-Clinical development – ca. 30% make it
-Regulatory review and approval – sign off by FDA and CDC
-Manufacturing – FDA inspects factory and drug labels
-Quality control – quality control review for safet
-Vaccine manufacture
-Vaccines are an antigen or foreign body that causes a reaction when introduced into the body. Foreign antigens illicit antibodies that fight the antigen.
-Live virus
-Inactivated virus
-Vaccine composed of a part of the virus
-Bacterial vaccines
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-Restrictions
oLimited doctor visits
oTelehealth for showing doctor your current medical signs and symptoms
oLimited medical access (lab)
-Management
oCardiac Disease
-CHF: take weight daily – call MD if any increase in weight, then get an Rx for Lasix (Furosemide)
-High blood pressure – keep BP < 140/90 with home monitoring
-ASCVD/high cholesterol – keep diet low in fat
-Lose weight
-Comply with medication regimen
- Continue ACE inhibitors and ARB medications
oDiabetes
-Taking daily blood sugar, keeping it in normal range, is sufficient to delay the A1c measurement.
-Follow a low sugar diet
-Lose weight
-Check daily – feet, hands – for dry and blue appearance – if blue, then call MD and show on Skype
-Moisturize skin to prevent dryness
oAsthma/COPD
-Stop smoking or use alternatives like Nicorette or generics
-Use rescue medications only when necessary and use ICS as prescribed on a regular basis
-Use breathing machine to maintain good volume capacity
-Buy an oxygen monitor to measure your oxygenation. Keep O2 at > 90%.
oThyroid
oPain (non-cancer)
oPain (cancer)
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What We Learned From Previous Epidemics / Pandemics
Statistics
Epidemics History (very frequent until recent times after 1950s)
Pearls
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What do we need to know about inhalant medications?
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Corona Virus (2019-nCoV)
1. What it 2019-nCoV is?
2. How it spreads?
3. Vaccines
4. Prevention
CDC Information
2019 Novel Coronavirus (2019-nCoV) is a virus (more specifically, a coronavirus) identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China. Early on, many of the patients in the outbreak in Wuhan, China reportedly had some link to a large seafood and animal market, suggesting animal-to-person spread. However, a growing number of patients reportedly have not had exposure to animal markets, indicating person-to-person spread is occurring. At this time, it’s unclear how easily or sustainably this virus is spreading between people. The latest situation summary updates are available on CDC’s web page 2019 Novel Coronavirus, Wuhan, China.
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Blood Shortage
1. Usage = 32K pints of blood used every day in US
2. Type of blood in short supply = Type “O”
3. Impact – 4.5M
a. 220mg-250mg of Iron lost for every donation – 24-30 weeks to replace iron
b. Normal Iron levels = 10-30 mmol/L (also ferritin < 10mcg/L)
4. Donor requirements (Red Cross) – Good health, weight >= 110 pounds, >= 17 years old
a. Eat iron rich foods (spinach, red meat, fish, poultry, beans, iron fortified cereals and raisins)
b. Drink an extra 16 oz fluids
c. Avoid fatty foods (hamburgers, fries, or ice cream)
d. No upper age limit
5. OTC and homeopathics, herbals, nutritional supplements are acceptable
6. Anti-depressants, Xanax, ADHD drugs -- OK
7. Restrictions (Red Cross) – anyone who has used self-injected non-prescription drugs, anyone who lived in UK for >= 3 months (and other parts of Europe) since 1980-1996 due to mad cow disease (bovine spongiform encephalopathy), heavy periods
a. Coronary artery disease
b. Beta blockers
c. HIV
d. Hepatitis
e. Active infection – wait 10 days after last antibiotic
f. Autoimmune disease
g. Receive a transfusion – wait 12 months
8. What categories of medications prevent people from giving blood?
a. Acne meds – Isotretinoin (d/t birth defects)
b. Finasteride and dutasteride (d/t birth defects)
c. Psoriasis meds – Soriatane (acitretin) – wait 3 years d/t severe congenital birth defects
d. Antiplatelet meds – wait 7-14 days for platelet donations
e. Blood thinners – blood doesn’t clot
f. Growth hormone injections
g. Multiple sclerosis medications – Aubagio – wait 2 years d/t birth defects
9. Medications that can’t be used to give blood (must wait one month until you can give blood)
a. Accutane, Amnesteem, Absorica, Claravis, Myorisan, Sotret, Zenatane (isotretinoin)
b. Proscar (finasteride)
c. Propecia (finasteride)
10. Recovery
a. Blood replenished within 24 hours
b. Red cells take 4-6 weeks
c. Must wait 8 weeks between giving blood
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Topics for Security Talk
1. PHI = personal health information
2. Security
a. Passwords – 8 characters can be hacked in less than 1 minute
b. Two Factor Authentication
c. Confidentiality refers to protection of information shared with an attorney, therapist, physician (or other) from being shared with third parties without express consent. ... Privacy, on the other hand, refers to the legal protection of personal medical information from being shared on a public platform.Mar 4, 2019
3. Privacy
a. Professional Code of Ethics
1. A pharmacist respects the autonomy and dignity of each patient. A pharmacist promotes the right of self-determination and recognizes individual self-worth by encouraging patients to participate in decisions about their health. A pharmacist communicates with patients in terms that are understandable.
b. HIPAA
i. The HIPAA Privacy Rule for the first time creates national standards to protect individuals' medical records and other personal health information. It gives patients more control over their health information. It sets boundaries on the use and release of health records.
1. www.hhs.gov › hipaa › for-individuals › faq › what-does-the-hipaa-priv...
ii. Treatment
iii. Administration/Utilization
iv. Payment
c. HealthIT.gov
i. The privacy and security of patient health information is a top priority for patients and their families, health care providers and professionals, and the government. ... The Security Rule sets rules for how your health information must be kept secure with administrative, technical, and physical safeguards. Dec 17, 2018 HealhtIT.gov
4. HIPAA
a. Treatment
b. Administration/Utilization
c. Payment
5. Controversy over Security
a. Pro: Data needed for treatment
b. Con: How data is used?
c. Long, detailed responses to data security before it can be used
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