Proactive - Interviews for investors

Imugene Ltd (ASX: IMU, OTC: IUGNF) chief medical officer Dr. Paul Woodard and managing director and CEO Leslie Chong talked with Proactive’s Tylah Tully about the latest results from the Phase 1b clinical trial of Azer-cel, the company’s CD19 CAR-T therapy.

Dr. Woodard, speaking from 2025 Tandem Meetings in Honolulu, shared the excitement around the trial's findings.

Azer-cel is being developed for patients who have relapsed after multiple lines of treatment.

The latest data reveals a 57% complete response rate, meaning no detectable lymphoma in these patients.

Chong highlighted that the addition of a low dose of IL-2 to Azer-cel has contributed to T-cell proliferation, helping patients’ immune systems fight back.

She emphasised that seeing durable responses in patients who have exhausted multiple treatment options is a significant achievement.

Dr. Woodard also underscored the importance of these results, stating that some patients are experiencing long-lasting remissions, with one individual remaining in complete remission for over ten months.

These findings reinforce the potential of Azer-cel in addressing an unmet need in relapsed and refractory lymphoma patients.

#Imugene #AzerCel #CAR_T #Biotech #Oncology #CancerResearch #ClinicalTrials #Lymphoma #MedicalBreakthrough #Investing

Olympio Metals Ltd has signed an Option Agreement with Clutch Group Pty Ltd for the sale of its remaining three Halls Creek tenements in Western Australia.

This transaction allows Olympio to focus on its upcoming drilling program at the Dufay copper and gold project in Canada.

Under the agreement, Clutch must meet minimum exploration expenditure commitments on exploration licences E80/5034, E80/5154, and E80/5220 during a due diligence period lasting until June 30, 2025.

Clutch has paid an upfront exclusivity fee of $25,000 and must spend a total of $80,000 on exploration.

If Clutch exercises the option, it will pay Olympio $100,000 for E80/5034, $30,000 for E80/5154, and $20,000 for E80/5220. Payments may be adjusted if any tenements are surrendered or expire during the due diligence period.

Olympio retains a future interest through two performance-based payments of $100,000 each—one upon defining a Measured JORC Mineral Resource of at least 50,000 ounces of gold at a minimum grade of 1.0 g/t gold, and another upon a Decision to Mine.

Olympio has stated that the Halls Creek tenements are considered non-core as it prioritises drilling at the Dufay Project, which is set to begin shortly.

#OlympioMetals #Mining #GoldExploration #CopperExploration #DufayProject #HallsCreek #WesternAustralia #CanadaMining #ExplorationAgreement #MiningInvestment #Drilling #JORC #MineralResources #MiningAustralia #MiningCanada #GoldMining #CopperMining #ResourceExploration #Geology #MiningNews #MineralExploration

Global Energy Metals CEO Mitchell Smith joined Steve Darling from Proactive to announce a significant milestone for the company’s strategic partner, NeoLithica Ltd. NeoLithica has entered into a direct lithium extraction (DLE) piloting agreement with Geo40 LLC to test lithium-brine sourced from its Peace River Project in Alberta.

Smith highlighted that NeoLithica is currently conducting a strategic evaluation to explore development options that will meet the growing demand for lithium in North America. The Peace River Project hosts one of Canada’s largest inferred lithium brine resources, positioning NeoLithica as a key player in the emerging lithium supply chain.

As part of the piloting agreement, NeoLithica transported 7,000 litres of lithium-rich brine from a producing well within the Peace River Project to Geo40’s test facility in Saskatchewan in early February. The goal of this pilot test is to validate Geo40’s innovative DLE technology, which is designed to efficiently extract lithium from brine deposits.

The results of the pilot program, expected in the coming weeks, will provide critical data to support NeoLithica’s economic assessment for producing lithium chloride (LiCl) concentrate and high-purity lithium carbonate (Li₂CO₃) suitable for battery applications. Additionally, NeoLithica intends to share the lithium chloride and lithium carbonate chemistry with potential customers for bench-top qualification testing, further advancing its commercialization efforts.

With this pilot program, NeoLithica and its partners, including Global Energy Metals, are taking a crucial step toward developing a sustainable lithium supply in Canada, reinforcing their role in North America’s clean energy transition.

#proactiveinvestors #globalenergymetalscorporation #tsxv #gemc #otcqb #gblef #Lithium #BatteryMetals #PeaceRiver #Mining #CleanEnergy #DLE #LithiumExtraction #MiningInvestment #NeoLithica #Geo40

Arizona Gold & Silver Vice President of Exploration Greg Hahn joined Steve Darling from Proactive to share exciting new exploration results from the company’s Philadelphia Project in Arizona. Recent core drilling has confirmed continuous gold mineralization at potentially bulk-mineable grades, further demonstrating the project's strong potential.

The latest results come from drill holes PC24-141 and PC24-142, completed approximately 100 metres north of previously reported hole PC24-140, as well as two new holes, GB-1 and GB-2. Hahn highlighted that both new holes intersected significant gold and silver mineralization, with notable intercepts including 62.18 metres at 1.27 g/t gold and 4.06 g/t silver and 40 metres at 1.0 g/t gold and 2.76 g/t silver

Both intercepts come from the Rising Fawn target, an area that continues to show strong mineral potential. The company is now preparing for the next phase of drilling, which will focus on testing the down-dip extension of these high-grade zones.

Additionally, results from three drill holes recently sent to ALS Labs are pending, while another three samples have been submitted to Skyline Labs in Tucson and are currently in preparation. These upcoming results will provide further insight into the project's expansion potential.

With continued exploration success, Arizona Gold & Silver is positioning the Philadelphia Project as a promising gold asset in the region, with ongoing drilling set to unlock even more value.

#proactiveinvestors #arizonagoldandsilverinc #tsxv #azs #otcqb #azasf #MiningUpdates #GoldExploration #PhiladelphiaProject #MiningDrilling #GoldAndSilver

Aftermath Silver CEO Ralph Rushton joined Steve Darling from Proactive to announce the latest assay results from the company's Phase 2 diamond drill program at the Berenguela silver-copper-manganese deposit in Puno, southern Peru. The results cover 23 additional drill holes from its ongoing 60-hole diamond core drilling program.

Rushton expressed optimism about the findings, particularly from Holes AFD064 to AFD077, which were geological investigation holes designed to test a north-south striking fault zone within the mineral resource. Additionally, Holes AFD105 to AFD113 served as resource infill holes on the eastern side of the deposit in an area known as the east-central anticline. These holes aimed to upgrade inferred resources to measured and indicated categories.

The results were consistent with previous drilling data and will be integrated into a revised block model, further refining Aftermath Silver’s resource estimates at Berenguela. With nearly 450 holes drilled in total, Aftermath Silver believes it has gathered sufficient data to finalize its geological model and metallurgical process work. The company expects to complete a Preliminary Economic Assessment by Q3 2025.

#proactiveinvestors #aftermathsilverltd #tsxv #aag #otcqx #aagff #mining #SilverMining, #BerenguelaProject, #Mining #Silver #Copper #Manganese #Peru #DrillingResults #BatteryMetals #ResourceModel #Investing

Digbee founder and CEO Jamie Strauss and US Gold Corp chairman Luke Norman and CEO George Bee talked with Proactive about the importance of independent ESG assessments in the mining industry.

Bee highlighted how Digbee’s evaluation of US Gold Corp provided a well-researched, independent analysis of US Gold’s environmental, social, and governance (ESG) performance. He noted that while the company had previous assessments, Digbee’s report offered a new level of detail and objectivity.

Norman emphasised the growing investor demand for ESG transparency, particularly among institutional funds. He explained that having an independent audit positions US Gold favorably for capital raising and project development. "Having a report that we've sanctioned put forward completely independent, I think, sits us above our peer group," he said.

Strauss discussed how US Gold could leverage the ESG assessment to enhance governance, attract investment, and engage with local communities. He pointed out that the report helps demonstrate responsible operations, which can improve access to capital and supply chain credibility.

For more insights into ESG compliance in mining, watch the full interview. Don’t forget to like this video, subscribe to Proactive’s YouTube channel, and turn on notifications for future updates.

#USGoldCorp #Digbee #ESG #Mining #GoldMining #ESGCompliance #SustainableMining #Investing #CapitalRaising #ProactiveInvestors

Oriole Resources PLC (AIM:ORR) CEO Martin Rosser talked with Proactive's Stephen Gunnion about the completion of phase 5 drilling at the Bibemi Gold Project in Cameroon. The programme included 56 holes totaling 6.9km at the Bakassi Zone 1 prospect. The final seven holes, for which results are awaited, are infill holes in the existing Mineral Resource Estimate (MRE) zone.

Rosser explained that the company is now reviewing the data to upgrade the JORC Inferred Mineral Resource estimate to the measured and/or indicated categories. He also noted that the current estimate stands at 375,000 ounces of contained gold, with 5.1 million tonnes grading 2.3g per tonne. Additionally, a higher gold price assumption—significantly more than the US$2,000 per ounce used in the last MRE—and all of the data now acquired could positively impact the size of the resource model.

Beyond Bibemi, Rosser provided an update on the Mbe field programme, where drilling began late last year. He highlighted that over 25% of the programme is already complete and emphasised the importance of gathering structural data from the initial drill holes to refine the geological model.

For more updates on Oriole Resources and its gold exploration progress, visit Proactive’s YouTube channel. Don’t forget to like, subscribe, and enable notifications for future updates.

For more updates on Oriole Resources and its gold exploration progress, visit Proactive’s YouTube channel. Don’t forget to like, subscribe, and enable notifications for future updates.

#OrioleResources #GoldExploration #MiningStocks #BibemiProject #MbeProject #GoldInvesting #MiningNews #CameroonGold #JuniorMining #GoldProspecting

Cosa Resources CEO Keith Bodnarchuk joined Steve Darling from Proactive to announce the company’s core drilling program has begun at the Murphy Lake North Project, a joint venture between Cosa Resources and Denison Mines Corp. The project, situated in the eastern Athabasca Basin of Saskatchewan, is operated by Cosa, which holds a 70% interest, while Denison retains a 30% stake.

This drilling campaign marks the first exploration drilling at Murphy Lake North since 2005—predating the discovery of the high-grade Hurricane Deposit by 13 years. Cosa Resources plans to complete approximately 1,600 metres of drilling, targeting the interpreted strike extension of Hurricane Deposit geology within Murphy Lake North and following up on historical uranium mineralization intersections.

Murphy Lake North is strategically located along the Larocque Lake trend, just 2.7 kilometers east of the Hurricane Deposit (Figure 2). Notably, Hurricane is recognized as the world’s highest-grade Indicated Mineral Resource for uranium. Several key members of Cosa’s current management, board of directors, and advisory team were instrumental in the discovery and delineation of the Hurricane Deposit for IsoEnergy Ltd. between 2018 and 2022, bringing extensive expertise to the Murphy Lake North exploration program.

In addition to advancing its exploration initiatives, Cosa Resources has entered into an agreement with Haywood Securities for a private placement offering of up to $5 million in aggregate gross proceeds. The company’s largest shareholder, Denison Mines, has indicated its intent to participate in the offering to maintain its holdings at approximately 19.95% post-transaction.

This drilling program and capital raise position Cosa Resources for a strong 2024, with renewed exploration efforts in the heart of the Athabasca Basin’s uranium-rich landscape.

#proactiveinvestors #cosaminingcorp #tsx #dml #cosa #nyseamerican #dnn #UraniumExploration #MurphyLakeNorth #AthabascaBasin #NuclearEnergy #MiningNews #Investing #DenisonMines #EnergyTransition #DrillingUpdate

Chesnara PLC (LSE:CSN) CEO Steve Murray talked with Proactive's Stephen Gunnion about the company’s recent M&A activity, financial resilience, and long-term growth strategy. He discussed the latest acquisition of a second batch of Canada Life policies, emphasising Chesnara’s ability to execute deals efficiently and integrate new books seamlessly.

Murray highlighted the company's strong solvency position, stating, “We've got excess capital available that we can continue to deploy on M&A.” With around £200 million in readily available capital, Chesnara sees further opportunities in the UK and the Netherlands while keeping an eye on offshore markets like the Isle of Man and Luxembourg.

He also addressed competition in the sector, noting that private equity interest has decreased slightly, making acquisitions more accessible. Chesnara is leveraging its strategic partnership with SS&C Technologies to improve policy migrations, ensuring smooth integration for new acquisitions.

Murray reiterated Chesnara’s financial resilience, pointing to its diversified business model and robust balance sheet. He also noted that the company has increased its dividend for 20 consecutive years, placing it among a select group of companies with such a track record.

For more insights, watch the full interview. Don’t forget to like, subscribe, and turn on notifications for more updates from Proactive.

#Chesnara #Finance #MergersAndAcquisitions #Investing #StockMarket #Insurance #DividendStocks #CEOInterview #BusinessGrowth #MarketTrends

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Ora Banda Mining Ltd.

Ora Banda has extended mineralisation at the Riverina Underground Gold Mine in Western Australia by a further 300 metres below the current mine plan, increasing the potential for an extended mine life at the Riverina Gold Camp.

Extensional drilling has expanded mineralisation in the central area, while greenfields drilling has led to the discovery of Little Gem, located 2.5 kilometres along strike from the mine.

High-grade gold results include 2.9 metres at 36 g/t gold and 2.9 metres at 18.9 g/t gold from deep drilling.

Extensional drilling returned 1.5 metres at 62.3 g/t gold, while Little Gem produced up to 4.6 metres at 7.4 g/t gold.

The company has described the results from Riverina Underground as "remarkable," noting the potential for a multi-year expansion in mine life.

The Little Gem discovery is also considered highly prospective due to its multi-lode structure.

Ora Banda plans to prioritise further exploration in the area.

To support ongoing drilling and resource development, Ora Banda’s board has approved $16 million for additional exploration at Riverina Gold Camp, along with $29 million to accelerate drilling and expand project infrastructure.

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