Proactive - Interviews for investors

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Prescient Therapeutics Ltd (ASX:PTX, OTC:PSTTF).

The company has received US FDA clearance to proceed with Phase 2 clinical trials for its Ras pathway inhibitor, PTX-100.

This study will focus on relapsed and refractory cutaneous T-cell lymphomas (r/r CTCL).

The decision follows the completion of a Phase 1b trial involving 19 T-cell lymphoma patients, which demonstrated an excellent safety profile and a 42% overall response rate.

Among evaluable r/r CTCL patients, five of seven experienced clinical benefits.

The global Phase 2 trial will enrol 115 patients across 15 sites in Australia, the US and Europe.

It will consist of two parts: dose optimisation and efficacy assessments. Primary endpoints include objective response rate, with secondary metrics focusing on progression-free survival, overall survival, safety, and quality of life.

The company describes FDA clearance as a transformative milestone, reflecting years of preclinical and clinical development.

Prescient aims to collaborate with global CTCL experts to deliver a safe and effective therapy for this area of unmet need. The announcement drove a 55% surge in the company’s shares.

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Standard Uranium Vice President of Exploration Sean Hillacre joined Steve Darling from Proactive to unveil an exciting development: the company has engaged Fleet Space Technologies to implement their cutting-edge ExoSphere Ambient Noise Tomography (ANT) and ground gravity surveys at the Davidson River project. This marks a significant milestone as Standard Uranium becomes the first uranium company to utilize this innovative technology in the southwest Athabasca Basin.

Hillacre explained that this multidisciplinary approach, leveraging Fleet Space’s end-to-end mineral exploration solution, will significantly enhance targeting precision. By integrating real-time ANT data with ground gravity measurements, the company aims to build upon historical work and overlay new geophysical insights across known uranium-bearing corridors on the Davidson River project.

Fleet Space’s ExoSphere technology is a game-changer in mineral exploration. It combines low Earth orbit satellite networks, satellite-enabled smart seismic sensors, and AI-powered predictive models to streamline the entire exploration process. Deployed in arrays across the exploration area, lightweight seismic sensors known as “Geodes” capture high-quality 3D ANT data from natural seismic vibrations in the ground. This data is transmitted via satellites to deliver actionable insights in real-time, accelerating exploration workflows while minimizing environmental impact.

Hillacre highlighted the benefits of this approach, emphasizing the enhanced speed and accuracy of data-driven targeting and the reduced environmental footprint. With this innovative partnership, Standard Uranium is well-positioned to unlock the full potential of the Davidson River project and redefine exploration in the Athabasca Basin.

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Athena Gold incoming CEO Koby Kushner joined Steve Darling from Proactive to announce the discovery of additional high-grade gold samples from the company’s reconnaissance prospecting program at the newly-acquired Laird Lake project in Ontario’s Red Lake Gold District. Spanning 4,158 hectares and covering 10 km, Laird Lake represents an underexplored yet highly promising portion of this prolific mining region.

The project, accessible by road, is situated approximately 10 km west of West Red Lake Gold Mines' Madsen Mine and 34 km northwest of Kinross Gold’s Great Bear Project.

Kushner highlighted a standout discovery, with one grab sample returning an impressive 373 g/t gold, marking the highest-grade sample ever collected at the site and one of the highest-grade surface grab samples publicly reported in the Red Lake Gold District. This finding underscores the project’s significant potential.

Geologically, the Balmer-Confederation contact, a key structural feature associated with gold mineralization in the district, plays a pivotal role in Laird Lake’s prospectivity. Over 90% of all gold mined in the district has been found within 300 meters of this contact, amplifying the project’s importance.

Looking ahead, Athena Gold plans to leverage these findings to guide a comprehensive property-wide geochemistry survey set to begin in H1 2025. The results of this survey are expected to refine drill targets for the company’s inaugural exploration program at Laird Lake, paving the way for potential resource expansion in one of Canada’s premier gold districts.

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#GoldExploration #MiningNews #RedLakeGold #NevadaGold #GoldMiningProjects #ProactiveUpdates #MiningInvesting #GoldDiscoveries

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Proactive's Billy Farrington takes Stephen Gunnion through Bitcoin’s eventful week and the state of the crypto markets as 2024 draws to a close Bitcoin hit a record $108,000 earlier this week, marking a 140% year-to-date gain. This milestone was influenced by positive sentiment following pro-crypto initiatives by President-elect Trump.

However, Bitcoin saw an 11% reversal, settling below $96,000 as market sentiment turned after the US Federal Reserve cut interest rates by 25 basis points but indicated it may tap the brakes in cuts going forward. This hawkish approach, with reduced expectations for reductions in 2025, contributed to broader market declines.

Bitcoin ETFs reached $120 billion in assets under management this week, nearly overtaking gold ETFs despite their 21-year head start. Farrington remarked that this was a remarkable achievement, though subsequent volatility widened the gap between the two.

Stay tuned to Proactive’s YouTube channel for more updates, and don’t forget to like, subscribe, and enable notifications for future content.

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Lumos Diagnostics Holdings Ltd (ASX:LDX, OTC:LDXHF) CEO Doug Ward takes Proactive's Stephen Gunnion through the company's achievements in 2024 and plans for the year ahead. Ward highlighted several key milestones, including the signing of a strategic partnership with Hologic and progress with its flagship products, ViraDx and FebriDx. He emphasised that FebriDx is transforming treatment by differentiating between bacterial and viral infections, helping to combat antibiotic resistance.

Ward also discussed Lumos’s collaboration with the Biomedical Advanced Research and Development Authority (BARDA), which funded a clinical trial to expand FebriDx's accessibility. He noted, “This is a huge win for Lumos, enabling us to go from 18,000 locations to 220,000 locations in the US with CLIA waivers.”

Furthermore, the company successfully secured A$10.00 million in funding, attracting key investors like Tenmile and Ryder Capital. Ward expressed optimism for 2025, focusing on revenue growth, the BARDA-funded trial, and enhancing their partnerships.

Visit Proactive’s YouTube channel for more insightful interviews. Don’t forget to like, subscribe, and enable notifications for future updates!

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Wedgemount Resources CEO Mark Vanry joined Steve Darling from Proactive to provide an operational update on the company’s West Central Texas oil and gas assets. Vanry highlighted significant advancements in Wedgemount’s enhancement and remediation program for the recently acquired producing oil and gas assets, known as Huggy, located in West Central Texas.

As part of the operational improvements, the company has repaired and replaced natural gas transmission flow lines where necessary, allowing for gas sales to third-party purchasers. This marks a critical step toward optimizing production and monetizing resources. Additionally, certain gas wells have been reclassified as oil wells with the Texas Railroad Commission (RRC) following successful chemical treatments that enhanced oil production rates.

Wedgemount also completed required compliance work with the RRC, which included well testing and ensuring adherence to operational regulations. Vanry noted that the company has initiated chemical treatments for wells, formations, and surface facilities, with plans to continue this program throughout 2025 to sustain and enhance production capacity.

One major milestone is the optimization of the Davis lease wells, which are now producing at rates above historical initial production (IP) levels. Management anticipates these wells will maintain strong production throughout fiscal year 2024, with projected output exceeding 20 barrels per day (bbls/day) in the first quarter of 2025.

Looking ahead, Wedgemount’s operational focus for 2025 includes ongoing maintenance chemical treatments across all leases to maximize reserve recovery and extend the productive life of its assets. The company remains committed to sustainable and efficient operations, ensuring both compliance and long-term profitability.

Vanry commented on the progress, stating, “Our team’s efforts to enhance and optimize the Huggy oil and gas assets have yielded excellent results so far. With improvements to infrastructure, successful chemical treatments, and robust compliance measures in place, we’re well-positioned to achieve sustained production growth and further unlock the value of these assets.

#proactiveinvestors #westmountreosurcescorp #cse #wdgy #otcqb #wdgrf

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Sprott Director of ETF Product Management Steve Schoffstall joined Steve Darling from Proactive to discuss the shifting dynamics of nuclear energy and uranium markets amidst rising electricity demands driven by AI and data centers. As technology companies seek reliable and sustainable energy solutions, Schoffstall highlighted the growing partnerships between tech giants and nuclear energy providers. He noted examples such as Amazon's agreement with Talen Energy as a signal of the sector’s potential.

“Nuclear energy is emerging as a key solution for clean, dependable power,” Schoffstall remarked, emphasizing its critical role in addressing the energy-intensive needs of AI development and large-scale data centers.

Despite recent volatility, Schoffstall expressed optimism about the uranium market, describing it as a "continued bull market" fueled by long-term demand for nuclear energy. He discussed the geopolitical factors shaping uranium production, such as Kazakhstan's growing ties with China, and the challenges this poses for Western markets.

Schoffstall also shared expectations for further domestic support for nuclear energy under the incoming Trump administration, particularly policies favoring U.S.-based energy production and investments in uranium mining.

The conversation also explored international commitments made at COP29, where nations pledged to triple nuclear energy capacity by mid-century. Schoffstall pointed out that Western utilities are likely to secure long-term uranium contracts as part of efforts to strengthen energy independence and reduce reliance on foreign supply chains.

As the world transitions to cleaner energy solutions, Schoffstall sees nuclear power playing an increasingly vital role, driven by both private-sector demand and government initiatives. With a bullish uranium market and expanding nuclear capacity, the sector is poised for significant growth in the years ahead.

#proactiveinvestors #hanetf #UraniumMinersETF #NuclearEnergy #SprottJuniorUranium

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Bradda Head Lithium Ltd (AIM:BHL, OTC:BHLIF, TSX-V:BHLI) executive chairman Ian Stalker talked with Proactive's Stephen Gunnion about the company’s latest progress at its San Domingo pegmatite project in Arizona.

Stalker shared details on plans to define a NI 43-101 compliant resource in 2025, moving toward production by late 2025 or early 2026. He highlighted new targets within the project area, such as Ruby Soho and Dragon, and emphasised the simplicity and cost-efficiency of the project, leveraging rented equipment and gravity separation processes to produce a quality lithium concentrate.

“We've been building momentum within San Domingo, where we’re now feeling confident about getting that resource out and bringing this project into production,” Stalker explained. He also noted the company’s strategic focus on reducing overheads and avoiding dilution, setting Bradda Head apart from peers in a tough lithium market.

Stalker reflected on broader lithium market challenges, including falling prices and reduced production, but remained optimistic about growing global demand for electric vehicles, particularly in the US and China. He hinted at opportunities for US-based projects like Bradda Head’s to attract interest from major players in the EV and battery industries.

For more updates on Bradda Head Lithium Limited and its projects, visit Proactive's YouTube channel. Don't forget to like the video, subscribe to the channel, and enable notifications for future content.

#lithiummining #BraddaHeadLithium #SanDomingoProject #ElectricVehicles #SustainableMining #LithiumResources #EVBatteryMaterials #MiningInvestments #ArizonaMining #ProactiveInvestors#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Graft Polymer (UK) PLC (LSE:GPL) chairman Dennis Purcell told Proactive's Stephen Gunnion that the proposed strategic acquisition of Awakn Life Sciences will help build an integrated mental health-focused entity. He sees this as essential for attracting investment dollars and addressing a significant unmet need in the healthcare sector.

Purcell, who has extensive experience in life sciences, emphasised the urgent need for innovation in mental health treatments, particularly after the challenges posed by the pandemic. He expressed optimism about the potential of neuropsychiatric treatments like those for alcohol use disorder and PTSD, pointing to promising results from mid-stage clinical trials. "The field of mental health needs new treatments, new modalities, because it's such a significant problem," he stated.

Visit Proactive's YouTube channel for more videos, and don't forget to give this video a like, subscribe to the channel, and enable notifications for future content.

#MentalHealthInnovation #GraftPolymer #Neuropsychiatry #BiotechInvesting #PTSDTreatment #AlcoholUseDisorder #HealthcareInnovation #BiotechNews #ProactiveInterviews#ProactiveInvestors#invest

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Bango PLC (AIM:BGO, OTCQX:BGOPF) chief marketing officer Anil Malhotra joined Proactive's Stephen Gunnion with details of a new agreement with Continente, Portugal's largest high-street retailer. This partnership leverages Bango's Digital Vending Machine (DVM) to offer Disney+ subscriptions to Continente loyalty card members at a discounted rate. Malhotra described the promotion as a compelling Christmas offer, allowing members to access Disney+ for €1.99 for three months, with a 30% cashback incentive on their membership cards.

The partnership underscores the growing versatility of Bango’s bundling technology, extending its reach beyond telecommunications into banking and retail. Malhotra highlighted that this deal aligns with consumer trends, revealing survey results showing 58% of British consumers value subscription gifting as a year-long benefit.

Looking forward, Bango anticipates strong organic growth and continued success with its digital vending machine, as it secures new clients and industries. “Disney+ was a highlight for 2024,” Malhotra said, adding that the company sees significant opportunities in banking, retail, and beyond.

Watch the full interview to learn how Bango is transforming subscription bundling globally. For more videos, visit Proactive’s YouTube channel, give this video a like, subscribe, and enable notifications for future content.

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