Proactive - Interviews for investors

hVIVO PLC (AIM:HVO) chief executive Yamin 'Mo' Khan talked with Proactive's Stephen Gunnion about the company's new £11.5 million contract with a top-tier global pharmaceutical company. The contract, involving an RSV human challenge trial, will utilise hVIVO's advanced facilities in Canary Wharf. Khan highlighted the importance of continued RSV research, even with vaccines available, emphasising the market's potential due to uncertainty about vaccine durability and effectiveness.

Khan also discussed hVIVO's diversification efforts. The company has expanded its laboratory capacity, launched new service lines, and signed contracts across laboratory services, outpatient studies, and patient recruitment. Despite these expansions, Khan affirmed that human challenge trials remain a core business, contributing to the company's strong order book.

Reiterating 2024 revenue guidance of £62 million, Khan expressed confidence in achieving a £100 million revenue target by 2028. He noted challenges in client contract signings but sees positive momentum in the pipeline of opportunities.

Learn more about hVIVO's growth and innovations in this Proactive interview. Be sure to like, subscribe, and enable notifications for updates on Proactive's YouTube channel.

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Digbee Limited founder and CEO Jamie Strauss and Ardea Resources CEO Andrew Penkethman talked with Proactive's Stephen Gunnion about Ardea'ss progress on its Kalgoorlie Nickel Project, Australia’s largest nickel-cobalt resource.

Penkethman emphasised the impact of Ardea’s second Digbee ESG assessment, highlighting significant improvements in their systems and processes. He shared insights into the definitive feasibility study, funded with a $98.5 million budget and supported by key partners Sumitomo Metal Mining and Mitsubishi Corporation.

The project, located in Kalgoorlie-Boulder, benefits from a supportive mining community and is designed to operate at low costs across multiple commodity price cycles. Penkethman stressed the company’s focus on further enhancing its ESG credentials, which are critical for engaging stakeholders and investors alike.

Strauss discussed how Ardea’s approach to responsibility and risk mitigation sets it apart in today’s evolving supply chains. He highlighted the importance of communication and preparation to meet modern industry standards effectively.

Visit Proactive's YouTube channel for more updates, and don’t forget to like the video, subscribe, and enable notifications for future content.

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Empire Metals Ltd (LON: EEE) Managing Director Shaun Bunn talks with Proactive’s Tylah Tully about the company’s metallurgical test results from its Pitfield project in Western Australia.

Bunn described the results as exceptional, achieving 95% recovery of titanium-bearing minerals using diagnostic acid leaching, marking a major milestone in the development of a high-grade titanium dioxide product with more than 95% purity.

Bunn said, “Our very first diagnostic test was hugely successful, achieving exceptional results with selective processing of weathered rock.”

He highlighted that the project was on track to produce high-value products for industries such as pigments and titanium metal manufacturing, with potential market prices ranging from $2,000 to $12,000 per tonne.

Bunn also discussed Empire Metals’ position in a tightening supply market, affected by reduced exports from Russia and rising tariffs in the US and Europe.

The company plans to optimise recoveries and finalise its flow sheet development, aiming to share significant updates early next year.

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M2i Global CEO Alberto Rosende joined Steve Darling from Proactive to address China’s recent decision to ban exports of certain critical minerals, a move that validates the company’s mission since its founding. Rosende emphasized that this geopolitical shift underscores the fragility of global supply chains and highlights the urgent need for diversification and domestic production.

China currently dominates the supply of critical minerals, controlling over 50% of the world’s germanium and nearly all gallium. Rosende noted that this export ban serves as a wake-up call for the U.S. to accelerate efforts to secure its supply chains and reduce dependence on foreign sources.

M2i Global’s strategic ecosystem is designed to address this challenge by offering turnkey solutions, including offtake agreements, government policy advocacy, partnerships with NGOs, and access to trusted laboratories. The company prioritizes ethical mining and recycling practices to create resilient domestic supply chains and support sustainable industry growth.

Rosende called for a united approach involving strategic investments, clear policy reforms, and innovations in recycling. By aligning public and private sector efforts, the U.S. can mitigate geopolitical risks, strengthen its position in the global market, and ensure long-term access to critical materials.

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Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Australian Vanadium Ltd (ASX: AVL, OTCQB: ATVVF).

Through its subsidiary VSUN Energy, Australian Vanadium is advancing Project Lumina, a modular and scalable utility-scale Battery Energy Storage System (BESS) using vanadium flow battery (VFB) technology.

The project targets medium-to-long-duration energy storage solutions for Australian energy markets.

Key appointments include Genus for power conversion and transformer systems, Sedgman for vanadium electrolyte storage and integration, and CellCube for technical expertise and power units. These partners bring expertise from high-profile projects, such as WA’s Kwinana lithium-ion BESS.

Project Lumina has progressed to Phase 2, refining assumptions from Phase 1, which demonstrated competitive levelised costs of storage at A$274/MWh for four-hour and A$251/MWh for eight-hour configurations.

Phase 2 focuses on finalising 100MW system designs, optimising a “deconstructed” BESS model for extended lifespans beyond 40 years, and engaging energy offtakers, securing land and evaluating funding strategies.

VSUN Energy highlights the importance of these partnerships in advancing utility-scale energy storage solutions, positioning Project Lumina as a leader in the renewable energy transition across Australia.

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Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Cobre Ltd (ASX: CBE).

The company has provided an update on its 2024 exploration program at the Ngami Copper Project (NCP) in Botswana’s Kalahari Copper Belt. Drill hole NCP56, located 2 kilometres from NCP55 and 7.5 kilometres from the Comet target, intersected widespread chalcocite mineralisation between 159 and 192 metres downhole, with grades ranging from 0.1% to 4% based on visual estimates and pXRF readings. Laboratory assay results are expected in February 2025.

These findings from the new Cosmos target suggest that copper mineralisation identified in NCP42 (15 metres at 0.5% copper and 13 g/t silver) may extend over 4 kilometres. The mineralisation is hosted in fine-grained cleavage and fractures, making it suitable for acid leaching and in-situ copper recovery (ISCR).

Cobre has completed 4,500 metres of infill drilling at the Comet Target, progressing towards refining the exploration target and establishing a JORC-compliant resource. The company sees these results as validating the continuity of mineralisation along the strike, reinforcing the significant potential of the Cosmos target area within NCP.

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Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Ionic Rare Earths Ltd (ASX: IXR, OTC: IXRRF).

The company has received support from Invest Minas, a Brazilian government investment promotion agency, for its plans to establish a rare earth magnet recycling facility in Minas Gerais, Brazil.

The project will be executed through Ionic’s Viridion joint venture with Viridis Mining and Minerals. The facility will utilise proprietary technology demonstrated in Belfast, Northern Ireland, to create a sustainable and independent rare earth supply chain.

The recycling facility will process pre-consumer magnet scrap and end-of-life magnets into rare earth oxides (REO) for manufacturing.

Ionic has partnered with Lab Fab, South America’s first rare earth magnet laboratory, to co-develop rare earth magnets. Strong government support highlights the project’s economic and environmental benefits, with a feasibility study confirming its profitability and sustainability.

Brazil is viewed as a significant market for Ionic’s technology, with magnet recycling seen as the first step toward an integrated domestic supply chain.

The country, the seventh-largest wind energy market globally, is expected to expand further, driving demand for REO materials. Additionally, Brazil’s emerging EV production capacity and growing advanced manufacturing sectors strengthen its position as a critical market for rare earths.

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Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Firebird Metals Ltd (ASX: FRB).

The company has signed an agreement with the Karlka Nyiyaparli Aboriginal Corporation (KNAC) for a mining lease at the Oakover Manganese Project in Western Australia.

The agreement ensures provisions for financial benefits, cultural heritage protection, ongoing engagement with KNAC and minimisation of operational impacts on Native Title rights, heritage and the environment.

Oakover spans 3,430 hectares and includes a mineral resource estimate of 176.7 million tonnes at 9.9% manganese, with an indicated component of 105.8 million tonnes at 10.1%.

The project plays a central role in Firebird’s strategy to produce battery-grade manganese sulphate.

Stage One of processing will occur in China, where Firebird is developing a manganese and tetra-oxide plant.

Stage Two will expand operations to China and a western location to meet increasing global demand by the decade’s end.

The project has an 18-year life-of-mine and is undergoing environmental studies, with referral to the EPA planned as part of a 12-month workstream.

Firebird aims to establish itself as a global leader in the manganese industry, supporting lithium-ion and sodium-ion battery advancements.

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Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) CEO James Graham joins Proactive’s Tylah Tully to discuss the approval the company has received from Indonesia’s Drug and Food Regulatory Authority (Badan POM) for a registrational Phase 3 clinical trial of RECCE® 327 topical gel (R327G) for treating diabetic foot infections (DFIs).

The trial will start in mid-December and represents a significant milestone for the company in the ASEAN region.

It will be conducted as a double-blinded, placebo-controlled study, enrolling up to 300 patients, with results expected in late 2025 and potential commercialisation in 2026.

The trial has support from Indonesian stakeholders, including the Ministry of Health and PT Etana Biotechnologies as well as the Australian Government. The project will cost approximately US$2 million, partially offset by Australia’s 43.5% R&D rebate.

This will be one of the largest DFI studies globally and the first in Indonesia, addressing urgent health challenges in a country with more than 19.5 million adults living with diabetes.

In Australia, Recce plans to launch a Phase 3 trial of R327G in 2025, aligning with its ASEAN-focused strategy.

These advancements bring Recce closer to commercialisation, with Graham acknowledging support from Australian and Indonesian authorities in expediting the process.

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Conavi Medical CEO Tom Looby joined Steve Darling from Proactive to share updates about the company’s innovative dual-modality catheter, developed at Sunnybrook Hospital in Toronto, which combines intravascular ultrasound (IVUS) and optical coherence tomography (OCT) to improve visualization during coronary interventions. These procedures are among the most frequently performed worldwide.

Looby highlighted the Novasight 3.0 system, which features enhanced imaging, AI-driven guidance to help doctors recognize tissue and size lumens, and a user-friendly design for seamless clinical integration. With regulatory approvals from the FDA and Health Canada, Conavi plans to commercialize the product within the next one to two years.

Medical professionals have responded positively to the dual-modality approach, which builds on prior innovations while providing a best-in-class solution for guiding complex cardiac procedures. This next-generation technology has the potential to significantly improve outcomes in coronary interventions globally.

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