Proactive - Interviews for investors

Recce Pharmaceuticals Ltd (ASX:RCE) CEO James Graham joins Proactive’s Jonathan Jackson to talk through the formal granting of a new Patent Family 2 by the China National Intellectual Property Administration. The patent, titled 'Copolymer and Method for Treatment of Bacterial Infection', covers RECCE® 327 (R327) and RECCE® 529 (R529). These compounds are used in the treatment of a wide range of common human infections, with the patent including claims related to methods of manufacture, administration and application. The patent is set to expire in 2035.

This marks the completion of Recce's portfolio of wholly-owned Family 2 Patents, ensuring that the company is patent-protected in all major global pharmaceutical markets, including China, Australia, the USA, Europe (specifically Germany, Spain, France, the UK, Italy and Sweden) and Japan. All these patents are due to expire in 2035.

Graham expressed gratitude towards the China National Intellectual Property Administration and emphasised the global coverage this patent secures. China, recognised as the world's second-largest pharmaceutical market, has shown consistent growth. In 2021, the market was valued at approximately US$140 billion, with a growth rate of around 3.2% in 2023. The growth is expected to continue, propelled by increasing demand, healthcare reforms, and government support for pharmaceutical R&D.

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Surefire Resources NL (ASX:SRN) managing director Paul Burton joins Proactive’s Jonathan Jackson to detail a groundbreaking process for extracting vanadium from magnetite deposits, highlighting a significant advancement in cost efficiency and environmental impact.

The company is securing intellectual property for this innovative process through a provisional patent, allowing 18 months for optimisation before full assessment by patent authorities. Traditionally, vanadium extraction involves high-heat kilns operating at 1100 degrees centigrade continuously, which results in substantial power usage, high temperatures and significant emissions. This method incurs immense capital and operating costs, estimated around $100-150 million for kiln construction and maintenance alone.

Surefire’s new method circumvents these issues by employing a leaching process with a combination of bleach jets and acids, directly treating the magnetite concentrate derived from mined ore. This approach has demonstrated a potential vanadium recovery rate of up to 97% after 24 hours, far surpassing traditional methods. Additionally, the process also recovers valuable titanium and iron, enhancing overall resource efficiency.

The company is currently scaling up this process for commercial application, expecting further results in the coming months and considering a mini pilot plant if results remain positive.

The financial implications of reducing capital and operating expenses are significant, potentially transforming the economic feasibility of the Victory Bore Mine deposit and offering a potentially lucrative opportunity for licensing the technology to other producers.

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Botala Energy Ltd (ASX:BTE) energy development manager Dr Steve Lennon sits down with Proactive’s Jonathan Jackson to discuss the progress the company is making with its pre-feasibility study for the Serowe coal bed methane (CBM) Project in Botswana.

Lennon explains how this stage is vital for transitioning from exploration licences to mining licences. The study focuses on three main areas - increasing gas production at the wellfield (upstream), processing and transportation of gas to central sites (midstream) and gas utilisation, mainly as liquefied natural gas for the Southern African market (downstream).

The options explored include on-site processing, a physical pipeline and a virtual pipeline for transporting liquefied natural gas. The initial financial assessments confirm the feasibility of these options, with straightforward technological requirements and well-advanced approval processes.

Furthermore, Botala Energy's longer-term objectives include substantial power generation using gas and solar energy. These ambitions necessitate incremental developments, such as establishing a gas power generation plant and a four-megawatt solar farm at the Leupane Energy Hub. A key partnership has been formed with AAA Energy, a developer of photovoltaic farms, to develop the initial 200-250 megawatts of solar power at Leupane. AAA will oversee the majority of the bankable feasibility study, which is expected to be completed by the end of the year.

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Synertec Corporation Ltd (ASX:SOP) executive director and CFO David Harris sits down with Proactive’s Jonathan Jackson to discuss how the company has revamped its financial framework by securing a A$15 million debt facility with Altor Capital Pty Ltd and completing a A$7 million equity placement.

These financial manoeuvres fortify the company's capital structure, fostering the advancement of its 100% renewable microgrid technology, 'Powerhouse'. This funding follows a robust March quarter where Synertec reported a significant 47% year-on-year increase in group revenue and income, ranging between $4.8 million and $5.2 million.

The debt facility is structured in two tranches, with an initial A$10 million available immediately and a further A$5 million pending review after the first tranche is utilised. This arrangement is poised to underpin the capital expenditure for the ongoing deployment of Powerhouse units, which operate on a Build Own Operate Maintain (BOOM) model. These units integrate predictive intelligence solar and battery systems to deliver renewable power.

Additionally, Synertec issued A$2.5 million worth of warrants to Altor, enhancing the capital flexibility and supporting the firm’s scalability and market penetration goals. This strategic financial setup not only underscores the bankability of Powerhouse but also aims to elevate Synertec's market position by enabling accelerated deployment of its microgrid solutions across potential domestic and international markets.

Furthermore, Synertec continues to expand its engineering services, securing new contracts and supporting innovative technology developments like green ammonia production with Jupiter Ionics, and contributing to infrastructure projects such as the Melbourne Underground Rail Loop.

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American Rare Earths Limited CEO Donald Swartz joined Steve Darling from Proactive to announce the results of a metallurgical study on the leaching extraction of Rare Earth Elements from Halleck Creek ore using low-temperature, direct acid leaching. The study, conducted by researchers at the Department of Mining and Minerals Engineering at Virginia Tech, was part of a three-year research contract awarded by the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy to Phinix, LLC, with American Rare Earth and Virginia Tech as team members.

Swartz highlighted that the positive results from the metallurgical study further confirm the findings of previous testwork carried out by Wood PLC. Independent technical studies, recently published and peer-reviewed, also underscore the economic potential of Halleck Creek ore. The studies revealed that 80% of REEs can be extracted using low-temperature, direct acid leaching, with fast leaching kinetics attributed to the ore's metamict allanite structure. Notably, 65% of REEs were extracted within the first 10 minutes of leaching, showcasing the ore's favorable characteristics compared to refractory ores like monazite or bastnaesite.

Furthermore, the Green and Smart Mining Engineering study demonstrated that Halleck Creek ore's high-grade rare-earth enrichment highlights its economic potential. Density and magnetic separation techniques have proven effective in separating and concentrating the rare earth elements, further enhancing the economic viability of the project.

These findings underscore the significant progress made by American Rare Earths Limited in advancing the development of the Halleck Creek project. With promising results from metallurgical studies and ongoing research efforts, the company is well-positioned to capitalize on the economic potential of Halleck Creek ore and contribute to the domestic supply chain of rare earth elements.

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Ocean Power Technologies CEO Philipp Stratmann joined Steve Darling from Proactive to share exciting news with Proactive regarding the company's recent achievement in completing multiple offshore demonstrations for potential customers of its Artificial Intelligence-capable Maritime Domain Awareness Solution, Merrows. These demonstrations were conducted utilizing OPT's Next Generation PowerBuoy, marking a significant milestone in showcasing the solution's capabilities to key stakeholders.

Stratmann emphasized that these successful field demonstrations position OPT uniquely, allowing the company to demonstrate the fully functional Intelligence, Surveillance, and Reconnaissance (ISR) capabilities of the PowerBuoy directly to potential customers. By bypassing traditional paper studies and accelerating the sales cycle, OPT demonstrates its commitment to providing innovative and practical solutions to meet evolving maritime security needs.

The Next Generation PowerBuoy, designed with survivability and cybersecurity in mind, offers a secure and reliable platform for collecting actionable intelligence in maritime environments. With the ability to securely connect to the Merrows solution from anywhere in the world, OPT provides customers with real-time insights and situational awareness to enhance maritime security operations.

Furthermore, OPT's solution is designed to integrate seamlessly with Advanced AI systems, leveraging data generated by the PowerBuoy to feed into Large Language Models and other AI technologies. This integration enhances the effectiveness of maritime surveillance and enables proactive decision-making to address emerging threats and challenges.

Looking ahead, OPT is scheduled to conduct further demonstrations for additional potential customers, including overseas prime contractors, in the coming weeks. These ongoing efforts underscore OPT's commitment to advancing maritime security capabilities and delivering innovative solutions to meet the evolving needs of the maritime industry.

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Skye Bioscience CEO Punit Dhillon joined Steve Darling from Proactive to share news announcing the company's uplisting of its common stock to the Nasdaq stock exchange, trading under the ticker symbol "SKYE." This achievement signifies a significant milestone for the company, reflecting advancements in its Phase 2 clinical programs, financial position, and shareholder base.

Dhillon further disclosed that Skye Bioscience reached another critical milestone by successfully dosing 56 patients with SBI-100 Ophthalmic Emulsion in its Phase 2a study and completing final study visits for all participants. SBI-100 OE, a cannabinoid receptor type 1 agonist administered topically to the eye, is designed to address the unmet needs of patients with elevated intraocular pressure related to primary open-angle glaucoma or ocular hypertension.

Notably, all treated patients completed the study without early discontinuations due to adverse events, demonstrating the safety profile of SBI-100 OE. The company anticipates releasing topline data for the entire study in the second quarter, marking a significant milestone in advancing its clinical program.

Skye Bioscience's move to the Nasdaq exchange underscores its commitment to enhancing visibility, expanding its investor base, and unlocking value for shareholders as it progresses in its mission to develop innovative therapies for ocular diseases.

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Dr. Raza Bokhari, Executive Chairman and CEO of Medicus Pharma joined Steve Darling from Proactive to shared insights with Proactive regarding the company's strategic initiatives, particularly its plans for a private placement of 100% unsecured convertible notes due in 2025. This move signifies a pivotal step in advancing the company's clinical development programs for novel and disruptive therapeutic assets.

The private placement commenced with the first closing on May 1, involving the issuance of approximately US$5,172,500 aggregate principal amount of notes. Additionally, Medicus Pharma retains the option to issue additional notes, with the potential to reach up to US$10 million aggregate principal amount post-completion.

Bokhari emphasized the company's unwavering focus on accelerating clinical development programs, underscoring the significance of the proceeds from the private placement. These funds will be allocated towards research and development initiatives, as well as fulfilling working capital needs crucial for advancing Medicus Pharma's therapeutic pipeline.

One of the notable endeavors within the company's portfolio is SkinJect, a pioneering non-invasive treatment for basal cell skin cancer. Leveraging patented dissolvable microneedle patch technology, SkinJect aims to deliver chemotherapeutic agents effectively to eradicate tumor cells. By commercializing this innovative solution, Medicus Pharma seeks to address critical unmet medical needs and enhance patient outcomes in the realm of dermatological oncology.

Through strategic financing and focused allocation of resources, Medicus Pharma is poised to bolster its clinical development efforts, bringing transformative therapeutic solutions to the forefront of patient care and medical innovation.

#proactiveinvestors #medicuspharmaltd #tsxv #mdcx #fda #clinicaltrials

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Baselode Energy CEO James Sykes joined Steve Darling from Proactive to provide insights into the company's inaugural drill program and ANT geophysical survey on its Bear and Hook uranium projects, respectively, situated in the Athabasca Basin region of northern Saskatchewan.

Baselode Energy has identified three primary target areas for drilling, strategically located at the intersection points of NE-SW-trending layers and cross-cutting NW-SE-oriented structures. The Bear drill program, spanning 1,500 meters with 6 to 8 drill holes, will target 2 to 3 different areas. The helicopter-supported program ensures efficient drill targeting while minimizing environmental impacts. The company has secured the necessary permits to execute the program.

Additionally, Baselode Energy announced a collaboration with Fleet Space Technologies to conduct an innovative high-resolution, ground-based, satellite-connected ambient noise tomography (ANT) survey. This survey will generate a 3D model of the subsurface over ACKIO and other areas of interest. Data from the survey is expected to be received and interpreted before the commencement of diamond drilling on the Hook project in June. The company has also obtained the required permits for this program.

These initiatives underscore Baselode Energy's commitment to advancing exploration efforts in the Athabasca Basin, leveraging cutting-edge technologies and strategic drilling targets to unlock the region's uranium potential.

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Alderan Resources Ltd (ASX:AL8) managing director Scott Caithness sits down with Propactive’s Jonathan Jackson to discuss results from last quarter and upcoming drilling at the New Years copper-gold prospect within its Frisco project in Utah, USA.

This decision follows advanced 3D modelling of the historic Cactus-Comet copper-gold mines and detailed analysis using drone magnetics, which revealed multiple promising copper-gold deposit targets. Notably, the New Years prospect is identified by a significant magnetic low anomaly, roughly twice the size of that at Cactus, and is part of a larger complex anomaly encompassing three lows. Positioned 400 metres from Cactus along the NE-SW Cactus Canyon Fault structure, New Years presents potential mineralisation over a 1-kilometre stretch, evidenced by historical shallow drilling results such as 13.7 metres at 2.32% copper.

Historically, the area has been underexplored since the 1960s and the existing shallow drilling has not adequately tested the anomaly. Drilling at New Years is scheduled to commence in late Q2 following permitting and site preparation, complemented by soil sampling to prioritise further drilling targets.

Simultaneously, Alderan is progressing with a stream and rock sampling program in its seven lithium project areas in Minas Gerais, Brazil. This effort is part of its exploration activities in the region known as Lithium Valley, with initial assay results expected early May.

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