Proactive - Interviews for investors

Accesso Technology Group PLC (AIM:ACSO, OTC:LOQPF) chief executive Steve Brown joins Proactive's Stephen Gunnion with details of a significant partnership with Saudi Entertainment Ventures (SEVEN).

Brown said the collaboration highlights accesso's strategy to grow its global footprint, underlined by its 2023 acquisition of VGS, now rebranded as accesso Horizon.

SEVEN, aiming to develop an expansive entertainment ecosystem across Saudi Arabia, plans to introduce over 21 attractions and more than 150 experiences across 14 cities. Horizon will be instrumental in managing admissions and entitlements for this vast project, offering comprehensive ticketing solutions and an overall visitor management system.

Brown said the deal represents accesso's most substantial engagement in the Saudi market to date, providing a solid foundation for further expansion within the region. The accesso Horizon platform supports dynamic pricing, among other advanced features, aligning with SEVEN's ambitious plans.

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ARway.ai Chief Executive Officer Evan Gappelberg joined Steve Darling from Proactive to announce multiple new SaaS developer sign-ups for its augmented reality experience platform, focusing on AR indoor navigation. These partnerships represent significant milestones in ARway’s mission to revolutionize human interaction with physical spaces through augmented reality.

Gappelberg explained that La Casa de Juana, a pioneering real estate platform based in Chile, has signed up for ARway's developer plan. La Casa de Juana specializes in offering comprehensive online services for evaluating and booking rental property tours. By leveraging ARway’s cutting-edge technology, they aim to prototype and introduce augmented reality real estate tours, enhancing their services and user experience.

In addition, Navigine, a global provider of hardware-based indoor navigation and wayfinding software, headquartered in New York and Berlin, has joined forces with ARway. Navigine’s expertise in utilizing WiFi and Bluetooth technologies, along with its blue dot technology, offers indoor navigation experiences. With Navigine's specialization in indoor navigation through hardware and beacons, covering over 3,000 unique facilities, their collaboration with ARway signifies a significant advancement in providing innovative indoor navigation solutions to users worldwide.

These partnerships underscore ARway’s commitment to expanding its capabilities and global reach, enabling augmented reality integration into everyday applications and revolutionizing the way people interact with physical spaces.

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Rakovina Therapeutics President and Chief Science Officer Mads Daugaard and Dr. Art Cherkasov from the Vancouver Prostate Centre and UBC joined Steve Darling from Proactive to unveil an exciting collaboration agreement between Rakovina and Dr. Artem Cherkasov, granting exclusive access to the proprietary Deep Docking AI Platform for DNA-damage response targets.

Dr. Cherkasov, who was appointed to Rakovina's scientific advisory board in November 2023, brings unparalleled expertise to the table. The collaboration aims to leverage the cutting-edge capabilities of the Deep Docking AI Platform, powered by advanced AI algorithms, to revolutionize the discovery and development of targeted cancer drugs.

By harnessing the power of AI-driven molecular analysis, Rakovina can rapidly evaluate billions of molecular structures to identify potential candidates for targeted cancer therapy. This innovative approach enables the team to focus on DNA-damage response-related vulnerabilities, which are prevalent across various types of cancer.

The Deep Docking AI Platform plays a pivotal role in this process, facilitating the rapid screening of billions of drug candidates against validated DNA-damage response targets. Through predictive modeling, the platform can assess safety, efficacy, and pharmaceutical properties, enabling Rakovina to prioritize the most promising candidates for further validation.

With access to the Deep Docking AI Platform, Rakovina can expedite the drug discovery process, accelerating the transition from preclinical research to human clinical trials and potential pharmaceutical partnerships. By combining AI-driven molecular analysis with established R&D infrastructure, Rakovina aims to spearhead the development of innovative therapies that target critical vulnerabilities in cancer cells.

This collaboration underscores Rakovina's commitment to advancing precision medicine and delivering groundbreaking therapies to patients in need. With the support of Dr. Cherkasov and the cutting-edge capabilities of the Deep Docking AI Platform, Rakovina is poised to make significant strides in the fight against cancer, offering hope to millions of individuals affected by this devastating disease.

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Cloud DX CEO Robert Kaul joined Steve Darling from Proactive to unveil some exciting developments as the company aims for a 100% renewal rate among its clients whose contracts are expiring in the first quarter of 2024. As of the current date, 11 out of 14 potential renewals have been secured, with the remaining 3 expected to follow suit.

Cloud DX specializes in executing contracts with various healthcare providers, offering Connected Health Kits that include approved medical devices and customized tablet computers. These kits are prescribed to patients for chronic care management, post-surgical recovery, remote rehabilitation, or palliative care purposes.

Kaul highlighted the diverse range of clients renewing their contracts in the first quarter, including Canadian hospitals, primary care clinics in Alberta, family health teams in Ontario, community paramedic services in Ontario, the Canadian Lung Health Foundation, and a Canadian Provincial health ministry. These clients collectively enrolled approximately 2,900 unique patients in 2023.

With the renewal of these contracts, Cloud DX has received orders for Connected Health Kits valued at $96,000 CAD. Furthermore, recurring subscription revenues from these contracts are projected to increase to $575,000 CAD per year, amounting to a total contract value of $1.5 million CAD by December 31, 2025. It's worth noting that Cloud DX maintains a robust gross margin of approximately 77%, as indicated in the company's most recent Financial Statements.

Overall, these developments underscore Cloud DX's commitment to advancing healthcare through innovative technology solutions, while also solidifying its position as a leader in the industry.

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Ramp Metals CEO Jordan Black joined Steve Darling from Proactive to introduce the company to the public domain and share exciting developments in the mining industry. With a background as a geotechnical engineer and experience in venture capital, including a notable role in taking GoldSpot public, Black has positioned Ramp Metals as a significant player in exploration, particularly focusing on nickel.

In the interview with Proactive, Black highlighted the company's primary project, the Rottenstone Southwest property, located approximately 30 kilometers from the historical high-yield Rottenstone mine in Saskatchewan, renowned for its nickel production. Inspired by the success of the historical mine, Ramp Metals is committed to further exploration in this area, aiming to uncover additional high-grade nickel deposits.

Preliminary geophysical surveys, notably a Time-Domain Electromagnetic (TDEM) survey, have revealed promising conductors and a magnetic structure reminiscent of significant discoveries in Australia. This discovery has garnered the attention of advisor Mark Bennett. Building on these promising findings, the company has initiated a 2000-meter drilling program, with over half already completed, targeting a principal conductor within the identified structure.

This exploration effort comes at a pivotal time when high-grade nickel is in increasing demand, particularly for use in batteries, amidst dwindling supplies in North America. Ramp Metals is strategically positioned to capitalize on this growing demand and aims to contribute to the exploration and development of critical nickel resources.

In summary, Ramp Metals' transition into the public domain marks an exciting chapter in its journey within the mining industry. With a focused exploration strategy, promising geophysical findings, and a dedicated team led by CEO Jordan Black, the company is poised to make significant strides in unlocking the potential of nickel resources, contributing to the growing demand for this essential commodity.

#proactiveinvestors #rampmetalsinc #tsxv #aac.p

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BenevolentAI (OTC:BAIVF) chief scientific officer Dr Anne Phelan joins Proactive's Stephen Gunnion with positive safety data from the Phase 1a, first-in-human, clinical study of BEN-8744 in healthy volunteers.

Phelan explained that BEN-8744 is a potent, selective PD10 inhibitor, uniquely designed to be peripherally restricted to mitigate CNS-mediated side effects associated with previous PD10 inhibitors. This design aims to ensure safety and tolerability, a primary goal in this phase of clinical research. She said the study successfully met its objectives, proving the hypothesis that peripheral restriction could eliminate adverse side effects, although it was not positioned to assess therapeutic value directly.

Phelan further detailed the study's methodology, highlighting its role in estimating the pharmacologically relevant exposure and understanding the drug's exposure profile, which is critical for determining the efficacious dose for future patient trials. The interview also shed light on BenevolentAI's innovative platform that integrates diverse data types, including genomics and transcriptomics, through advanced AI and machine learning models.

This platform identified PDE10 inhibition as a novel approach for treating ulcerative colitis, despite the lack of direct literature linking PDE10 to the condition, demonstrating the company's proprietary method in target discovery.

Looking ahead, Phelan mentioned ongoing Biomarker Qualification studies and extended toxicology studies to pave the way for phase 1b and phase 2 studies, with an emphasis on ensuring longer dosing durations are safe for patients. This step is pivotal for moving BEN-8744 towards clinical efficacy trials, underlining BenevolentAI's commitment to advancing drug development through AI-enabled insights.

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Caledonia Mining Corporation PLC (AIM:CMCL, NYSE-A:CMCL) chief executive Mark Learmonth tells Proactive's Stephen Gunnion the company faced a challenging 2023, primarily due to poor production in the first half of the year at its core asset, the Blanket Mine in Zimbabwe, and an underperformance in a small-scale oxide project. However, the latter half of the year saw substantial improvement in Blanket's production.

The company also encountered increased costs, notably in labour and electricity, along with one-off administrative expenses, which have been addressed. To mitigate labour costs, Caledonia initiated more efficient timing systems for workforce management, particularly for their new, larger, and lighter shaft operations. For electricity, the company plans to reduce consumption and has already made strides by substituting diesel usage with a solar project.

Due to improving cash flows, Learmonth said Caledonia maintained its quarterly dividend at 14 cents.

The underground exploration program at Blanket resumed last January, showing promising drill results that led to extending the mine’s life considerably, from 2034 to 2041. Learmonth said this extension will be further supported by an upcoming new resource statement. Moreover, Caledonia is progressing with an updated feasibility study on the Bilboes sulphide project, aiming to publish it in the coming months.

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Good morning from London where the FTSE 100 gained on the final morning of this shortened Easter trading week.

Festive cheer was limited though, as Thames Water confirmed shareholders would not provide it with a £500 million rescue package, prompting speculation over the London supplier’s future.

On a more positive note, JD Sport pleased the market with an optimistic full-year report, in which it said conditions would improve this year and that it was outperforming rivals.

Elsewhere, Spirent Communications soared after accepting a takeover offer from Keysight, which represented a 14% premium on its share price at Wednesday’s close.

And finally, ONS figures released on Thursday morning revealed the UK’s technical recession over the second half of last year was slightly less severe than previously thought, with growth flat over the third quarter and down 0.3% in the fourth.

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Rowena Smith, CEO and managing director of Australian Strategic Materials Ltd (ASX:ASM), joins Jonathan Jackson in the Proactive studio to discuss the company’ s Dubbo Project, in Central West New South Wales. This project aims to extract and process critical minerals and rare earth elements, crucial for various high-tech applications.

Last week, the project received a significant boost with a Letter of Intent (LoI) for a US$600 million debt funding package from the Export-Import Bank of the United States, adding to a previous A$200 million Letter of Support from Export Finance Australia (EFA). This financial backing underscores the strategic importance of critical minerals and the global interest in securing supplies for future technological and industrial use.

The Australian Government's focus on critical minerals reflects a broader international trend towards securing supply chains for essential resources, particularly those pivotal for technological advancements and sustainable development.

Furthermore, ASM has contracted Bechtel Mining and Metals, Inc for Front-End Engineering Design (FEED) services. Bechtel will develop the project's engineering design, integrating its extensive experience in constructing large-scale industrial projects, which will enhance the project's feasibility and operational planning.

This collaboration and the secured funding are pivotal steps towards completing a comprehensive feasibility study for the Dubbo Project, setting the stage for its development and operational phases.

#ProactiveInvestors #AustralianStrategicMaterials #ASX #CriticalMinerals #DubboProject #RareEarthElements

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FireFly Metals Ltd (ASX:FFM) managing director Steve Parsons joins Jonathan Jackson in the Proactive studio to discuss the recent A$52 million placement, a move that Parsons says will primarily fund the advancement of the Green Bay Copper Project in Canada.

Looking ahead, Parsons outlines the company’s exploration priorities at Green Bay, with the next six months set to be a period of intense activity and development as the company drives forward with its strategic vision.

#ProactiveInvestors #FireflyMetals #ASX #Copper

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