• In this episode, Duane Mancini is joined by Harrison Lands, Director of Translational Sciences at UPMC Enterprises. Harrison brings a unique perspective, shaped by his background as a physician, MBA, consultant, and now investor. We delve into the workings of UPMC Enterprises, exploring their investment thesis – the who, what, how much, when, and how their fund operates. Harrison also sheds light on the powerful advantages of UPMC's payer/provider integrated medical system and its impact on fostering innovation. The conversation touches on the vibrant Pittsburgh life science community, Harrison's time at the University of Virginia, and insights from CvilleBioHub. Tune in to understand how a major integrated health system strategically invests and drives translational science forward.
• Harrison Lands LinkedIn
• UPMC Enterprises Website
• Duane Mancini LinkedIn
• Project Medtech Website
• Project Medtech LinkedIn

• In this episode, Duane Mancini sits down with Isaiah Kaiser, Co-Founder and CEO of Auxilium Health, and Elyse Ball, Vice President of Programming at Bounce Innovation Hub. Fresh off Auxilium Health's exciting $1.5M oversubscribed pre-seed round and new office at Cleveland Clinic, Isaiah returns to share their journey since his first appearance in episode 147. Elyse discusses the vital role of Bounce Innovation Hub in supporting startups and how her journalism background aids in her work. Together, they delve into navigating the regional iCorp program and the JumpStart accelerator, offering invaluable advice for raising capital and maneuvering the startup landscape. Tune in to hear their insights and get a glimpse into Auxilium Health's next major milestones.
• Isaiah Kaiser LinkedIn
• Elyse Ball LinkedIn
• Duane Mancini LinkedIn
• Auxilium Health Website
• Bounce Innovation Hub Website
• Project Medtech Website
• Project Medtech LinkedIn

• In this episode, Duane Mancini interviews Devon Campbell, Christie Johnson, and Dan Tipaldo to continue the theme from episodes 207, 208, and 209 about how startups can effectively 'do it yourself' when budgets are tight, this episode tackles the next frontier: Artificial Intelligence. We acknowledge that resource-strapped startups need to be resourceful, but how can AI help avoid costly mistakes and actually accelerate progress? Join us as we explore practical ways startups can leverage various types of AI – often at low or no cost – to improve internal processes, support essential tasks, and ultimately keep moving the needle forward without breaking the bank. Tune in to learn how AI can become a powerful tool in your startup's DIY toolkit.
• Devon Campbell LinkedIn
• Christie Johnson LinkedIn
• Dan Tipaldo LinkedIn
• Duane Mancini LinkedIn
• Prodct Website
• Project Medtech Website
• Project Medtech LinkedIn

• In this episode, Duane Mancini interviews Joao Rezende-Neto on his remarkable journey through the global landscape of medicine and innovation. From medical training in Brazil to a trauma fellowship in the US, exposure to Boston's cutting-edge medical advancements, and experiences in Canada, this episode explores the unique insights gained from navigating diverse healthcare systems. Discover how these international experiences spurred the drive to bring innovative solutions across borders, adapting ideas from Boston for Brazil and vice versa. We delve into the critical considerations of clinically relevant research, fostering effective collaborations between clinicians and business leaders, and the balance of scientific rigor with economic impact. Hear firsthand about the challenges and rewards of being a physician entrepreneur dedicated to advancing healthcare on a global scale. Tune in for a unique perspective on the intersection of global medicine, innovation, and entrepreneurial spirit.
• Joao Rezende-Neto LinkedIn
• InventoRR Md LinkedIn
• AbClo Website
• Duane Mancini LinkedIn
• Project Medtech LinkedIn
• Project Medtech Website

• In this episode, Duane Mancini interviews Kelly Collier at LifeX on the dynamic life science startup ecosystem thriving in Pittsburgh. We explore the unique synergy between major academic institutions like the University of Pittsburgh and Carnegie Mellon University, and healthcare giants such as UPMC and Allegheny Health Network. Discover Kelly's entrepreneurial journey and learn how LifeX provides crucial support and programming for emerging life science companies. We also discuss the common pitfalls startups face and the specific advantages Pittsburgh offers to innovators. Tune in to understand the key ingredients fueling Pittsburgh's rise as a life science hub.
• Kelly Collier LinkedIn
• LifeX Website
• Duane Mancini LinkedIn
• Project Medech Website
• Project Medtech LinkedIn

In this episode, Duane Mancini explores the critical aspects of medtech regulation and product development with Niki Caporali Spaniel and Chad Gibson of CMD Medtech. Niki shares her expertise in post-market clinical follow-up and navigating the complexities of the Medical Device Regulation (MDR). Chad emphasizes the importance of integrating cybersecurity throughout the product lifecycle, rather than treating it as an afterthought. They both discuss the significance of robust design controls, the pitfalls of inadequate planning, and the power of leveraging professional networks. The conversation highlights how regulatory considerations should inform decisions across all business functions, and the crucial role of thorough market research in achieving success. Tune in for valuable insights on building compliant, secure, and market-ready medical devices.

Niki Caporali Spaniel LinkedIn

Chad Gibson LinkedIn

CMD Website

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In this episode, Duane Mancini delves into the life science ecosystem in Kentucky with Christin Godale, Executive Director at LifeSciKY, and Nicholas Lyktey, Chief of Laboratory Operations at Gravity Diagnostics. Christin discusses the collaborative, bipartisan efforts driving innovation in the Commonwealth, including the launch of strategic initiatives and the benefits available to participating companies. Nicholas shares the remarkable growth story of Gravity Diagnostics, from a startup with 30 employees to a powerhouse of 330, highlighting the challenges and successes of rapid scaling. We also explore the partnership between Project Medtech and LifeSciKY and how it is shaping the future of the industry in Kentucky. Tune in to discover how strategic investments and collaborative partnerships are fueling a life science revolution in the heart of the Bluegrass State.

Christin Godale, PhD  LinkedIn

Nicholas Lyktey LinkedIn

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In this episode, Matt Sokany joins Duane Mancini at Project Medtech to share his extensive experience in the medtech industry, from his time at Ethicon Endosurgery (Johnson & Johnson) to his impactful journey in the startup world. Matt details his strategic approach to building successful companies, including his remarkable exit with New Wave Surgical, which raised less than $3M and sold for $115M. Matt also discusses his leadership at Standard Bariatrics, emphasizing the importance of setting quarterly and two-year goals, fractionalizing key departments like CFO and regulatory/quality, and securing strong legal and board support. He highlights the crucial role of company culture, clear communication, and the necessity of over-funding to navigate the unpredictable startup landscape. Tune in for invaluable insights on building a thriving medtech startup from a seasoned industry leader.
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Matt Sokany LinkedIn

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In this episode, Tim Grace, Managing Partner at Techstars Columbus, joins Duane Mancini to unpack the dynamic world of startup acceleration and venture funding. Tim shares his journey from a tech background to leading a pivotal Techstars program, and discusses the creation of the LongJump venture fund. We delve into the origins and growth of Techstars Columbus, exploring the successes of its various cohorts and the unique ecosystem it fosters. Tim provides invaluable insights into common startup pitfalls, particularly the critical mistake of neglecting customer validation. We also cover essential strategies for preparing for fundraising, and the key factors investors look for. Tune in to gain a behind-the-scenes look at how Techstars Columbus is shaping the future of innovation and entrepreneurship in the Midwest.
Tim Grace LinkedIn

Techstars LinkedIn

Techstars Website⁠

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In this episode, Antony Watson, COO of Xenocor, joins Duane Mancini to share his journey from Medtronic sales rep to startup founder. Antony discusses his experience in the operating room, observing surgical cases firsthand, and how this unique perspective shaped his leadership approach and ultimately prepared him to launch and lead Xenocor. Discover how valuable lessons learned in the field can translate to success in the startup world. Tune in for insights on transitioning from a corporate environment to the challenges and rewards of entrepreneurship in the medtech industry.

Antony Watson LinkedIn

Xenocor LinkedIn

Xenocor Website

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