SetSet with April Pride

Psychedelics and Aging: Meaning, Grief, and Integration in Later Life


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116. Psychedelics and Aging: Meaning in Later Life

An educational conversation on psychedelics and aging, exploring meaning-making, grief, safety, and integration through lived experience and research.

Episode Summary

What happens when psychedelic experiences arrive later in life—after careers, caregiving, grief, and loss have already shaped the nervous system? In this episode, April Pride sits down with journalist and author Abbie Rosner to explore psychedelics and aging through the lens of elderhood, meaning-making, and maturity. Rather than framing psychedelics as a return to youth, this conversation looks at how these experiences can land differently for older adults—bringing reflection, perspective, and emotional capacity rather than novelty or intensity. Together, April and Abbie discuss research on end-of-life anxiety, lived experiences of grief and joy, and why preparation, support, and integration matter more than peak experiences. This episode offers a grounded, harm-reduction–oriented exploration of what psychedelics may offer later in life—without hype, pressure, or promises.

🔵 Key Takeaways

Psychedelics often land differently later in life because the nervous system carries decades of lived experience.

Elderhood is not decline—it’s integration of youth, age, wisdom, and impermanence.

Research on psychedelics and end-of-life anxiety points to increased emotional capacity, not the elimination of grief or fear.

Challenging experiences are not uncommon, but preparation and support can reduce long-term difficulty.

Community becomes increasingly important for integration, care, and meaning as we age.

🔵 Timestamps

[00:00] Why psychedelics and aging require a different conversation[02:30] Abbie Rosner’s journey into psychedelics later in life[05:30] Seniors vs. elders and why language matters[07:15] Elderhood as integration, not decline[11:25] Meaning making, mortality, and end-of-life research[14:20] What older adults seek from psychedelic experiences[21:00] Harm reduction, challenging experiences, and safety[26:00] Preparation pathways: legal, underground, and supported options[29:00] Psychedelics, grief, and emotional release[33:00] Community, mutual care, and aging with intention[36:50] Integration over intensity: closing reflections

🔵 Guests

Abbie Rosner is a journalist and author focused on psychedelics and aging, and elderhood. Her forthcoming book explores how psychedelic experiences intersect with meaning making, grief, and community later in life.Follow Abbie Rosner: Elderevolution on Substack | Instagram — @elderevolution

🔵 Additional Resources

SetSet Psychedelic Cards

Women in the Wild application

Learn more about this episode: https://aprilpride.substack.com/p/psychedelics-and-aging

Hosted by April Pride

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