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Featured guest: Amy VandenBerg, PharmD, BCPP

Objectives

· Identify appropriate selective serotonin reuptake inhibitors for the management of depression in pediatric patients and how they work.

· Identify appropriate serotonin-norepinephrine reuptake inhibitors for the management of depression in pediatric patients and how they work.

· Discuss the black-box warning associated with these medications.

· Identify symptoms of serotonin syndrome.

· Identify symptoms of discontinuation syndrome.

Resources

· Selective serotonin reuptake inhibitors (StatPearls)

· Demystifying serotonin syndrome (or serotonin toxicity) (Canadian Family Physician)

· Antidepressant discontinuation syndrome (Canadian Medical Association Journal)

· Antidepressants and the FDA’s black-box warning: determining a rational public policy in the absence of sufficient evidence (AMA Journal of Ethics)

· Serotonin norepinephrine reuptake inhibitors: a pharmacological comparison (Innovations in Clinical Neuroscience)

CME Credits available: 0.5

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