Richard Jones, professor of Physics at the University of Sheffield, looks at how we can manipulate matter at the level of individual atoms and molecules and the possible impact this will have on advances of medicine, energy and information technology.

Writer and journalist Nicholas Fogg, sheds light on the historical conundrums of Shakespeare's sonnets. The sonnets represent one of the great literary enigmas and have given rise to endless speculation and debate.

Stuart Roberts, research fellow at the University of Reading, discusses the decline of bees and its effect on the environment. Evidence is presented on the state and trends of bees, the likely drivers of change and the possible long term effects.

This lecture looks at medicines available over the counter from pharmacies as well as those available from supermarkets, grocery stores and garages. Trained pharmacist Denise Taylor discusses readily available medicines and how safe they are.

Roger Vlitos, writer and photographer, discusses how Stonehenge has been seen in every age, from its first appearance in medieval manuscripts to the present day.

Professor Tom Kirkwood, Director of the Institute for Ageing and Health at Newcastle University, explores how the ageing process is influenced by a broad range of lifestyle and environmental factors

Dr Jane Davis tells stories about the value of great books in ordinary lives. Jane left school at 16 with 2 GCSEs but now leads an organisation which wants a bigger place in the nation's heart for books and reading. Later in life she returned to education and graduated with a 1st class degree in English and spent 3 years writing a PhD.

Professor Anil Markandya, from the Department of Economics & International Development, gives the Charter Day lecture in which he explores more sophisticated ways of measuring a country's wellbeing than just looking at GDP; these include assessing its ecological footprint, rating in the Corruption Perception Index and number of happy life years. Using these techniques, there are some surprising winners and losers.

Professor Chris McMahon, from the University's Department of Mechanical Engineering, considers some of the most complex design challenges faced by engineers through the ages, from designing ships in the 17th century, to the modern computer-assisted design of cars and planes

Professor Melanie Welham and Dr Paul De Bank from the University's department of Pharmacy and Pharmacology talk about stem cell research and regenerative medicine.