Ram Arora Podcasts Library

Ram Arora Podcasts Library

By Ram AroraBusinessNon-Profit
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Ram Arora Podcasts Library episodes

  • Covid toes: A perplexing medical finding in Covid 19

    Covid toes are the most common dermatological manifestation of Covid 19. They are seen in predominantly white caucasian ethnicity and patients are usually young and thin. They also seem to occur in the later half of clinical disease. Most cases are asymptomatic and self resolve within 15-30 days. What's quite fascinating about them is that majority of them test negative on Covid 19 RT PCR and Antigen tests. Listen to the podcast to discover what might be causing that and what might be the clinical significance and future application of this finding. 


    Listening time : Approx 20mins 

    20 min
  • BBC interview with Ben Prater (07/10/21) : Covid toes
    Chilblains like lesions (CLL) are the most common cutaneous manifestation of covid 19. These tend to usually occur in the Caucasian paediatric population / young adults. Quite baffling is the associated fact that the majority of these patients test PCR negative to covid. These young patients tend to produce a very early onset copious amount of interferon 1 IgA subtype which essentially defeats the virus very early on, thus preventing detectable levels of antibodies to be built up subsequently. Immunofixation finds these IFN - 1 deposits in covid toes. These are thus now thought to be due to a combination of endothelial dysfunction and immune mediated response "activation loop" following covid 19 infection.
    5 min
  • BBC wiltshire : My thoughts on winter pressures facing the NHS and how the general public can reduce their risk

    The NHS enters the winter phase surrounded by the "perfect storm" with an unprecedented backlog of cases, the threats from Flu and RSV which may act synergistically with Covid 19 infection and cause infections of greater severity, an expected increase in wintertime hospitalisations from non-communicable diseases (eg Asthma, COPD, IHD), staff and equipment shortages and what is an already overburdened service seeing an unexpectedly high demand on its resources. The fact that > 75% of our population is double vaccinated is indeed a feat of science. Vaccine confidence nationally seems to be high. The risk however is "Vaccine Over-confidence", where all other preventative measures such as social distancing, wearing masks, well-ventilated workspaces, meeting people outdoor wherever possible is put aside for the sense of security that being vaccinated brings. Indeed there is data from Israel that antibody levels wean after 6 months or so. This may increase susceptibility to infection but the vaccines still continue to provide protection from developing a serious infection. There is also data that records a three-fold reduction in transmission in those vaccinated. 99.5% of the mortality in the last 6 months occurred in those who weren't double vaccinated at the time of infection. There is the risk of a "triple lethal combination" of Flu, RSV and Covid 19 working together to overwhelm an already outstretched health service. The Covid 19 causing virus may also experience a natural "selection pressure" when it will need to compete with the other winter prevalent respiratory viruses and this may also force a new mutation. 


    What could the general public do to minimise their risks? The unidimensional approach of either focusing on any one intervention such as testing, lockdowns or mass vaccinations are bound to fail and a multidimensional approach will need to be adapted to keep ourselves safe and to safeguard the NHS. This means utilising any and all of the above options should they be deemed necessary along with basic pillars of managing respiratory infections such as face masks, social distancing, hand hygiene,  good ventilation etc. This will safeguard us from both Covid 19 and Flu/ RSV infections common in the winter season. Additionally, it is important for those who are vulnerable to self assess their risk and exercise greater caution. By exercising the above precautions the population could safeguard themselves and others dear to them. It is a fallacy to assume that the governments would need to walk a tight rope between securing the economy vs managing the covid pandemic as the data from other countries already shows that for the economies to be truly secured, the covid 19 threat needs to be managed first and foremost. 


    The Government was given guidance around managing Covid 19 in Mid July with respect to the planning for the 2nd Winter with Covid-19. We start the winter with a higher number of cases as compared to the same time last year.  We hope that this guidance is heeded this time around and a more proactive approach is adopted by the policymakers. Our personal freedoms are important but when they interfere with the safety of others then it becomes a separate matter altogether and leadership needs to step in. Getting this timing right for such a government intervention will always be a difficult act to pull off for anyone in power. 


    References 

    1. https://blogs.bmj.com/bmj/2021/09/09/john-middleton-is-the-nhs-prepared-for-the-coming-winter/

    2. https://www.bmj.com/content/374/bmj.n2270

    3. https://acmedsci.ac.uk/file-download/4747802

    6 min
  • BBC Wiltshire interview with Ben Prater 080721 : My views on lockdown easement & exercising caution
    BBC Wiltshire today : My thoughts on lockdown easement and the concepts of personal responsibility, personalised risk and exercising caution. Short interview lasting 3 minutes. The important thing to note here is that there is only a modest protection provided by the vaccine in acquiring an infection post vaccination but the overall protection is bolstered by subsequent significant reduction in transmission rate, development of serious illness and reducing deaths. The common sense approach would be to use other measures such as masks and personalised risk assessment of individual circumstances whilst cautiously coming out of a lockdown so as to not get infected at the first place and thus keeping the prevalence rate of the virus low. Greater spread of the virus could again lead to development of new variants some of which could be resistant / less susceptible to the vaccines. Indeed a tricky balancing act for the government.
    596 hr 32 min
  • BBC Wiltshire : General practice perspective of impact of Long Covid, interview with Ben Prater
    Long covid seems to affect 14 % of those with Covid according to a recent study published in the BMJ in May 2021 . The UK by June 2021 had 4.6 million confirmed cases of covid. The reality is that British general practice hasn't seen as many cases of long covid as were expected. Patients self managing and most patients having a self resolving 12 week illness may be the causes here. But we know that covid affects the vulnerable communities disproportionately and these communities are less likely to reach out and seek help. In terms of symptoms, more than 50 sequelae post covid are defined and seem to affect almost every system of the human body. Self help resources mentioned are 1. https://www.yourcovidrecovery.nhs.uk/ 2. https://www.post-covid.org.uk/ 3. https://www.rcot.co.uk/how-manage-post-viral-fatigue-after-covid-19-0
    6 min
  • BBC Wiltshire : My thoughts on the B1617.2 variant (aka the "Indian variant") and what works.
    This is my interview recorded with BBC Wiltshire on 19/5/21 at 7am GMT. Here I discuss with Ben Prater about what is known about the Indian variant and what weapons we have in our arsenal to combat it. The mental health impact of the pandemic is also explored. The clip concludes with my thoughts on how to reach the difficult to reach populations so that we have an impenetrable vaccine coverage across the UK population.
    5 min
  • Punjabi Detox podcast : how did UK fare during 2020, the year of the lockdown

    Punjabi Detox is a channel geared towards the subsection of the Asian population struggling with alcohol addiction in the United Kingdom. In this episode we look at the new data from the Office of national statistics which has recorded a 19.6% increase in alcohol specific mortality.


    This data is available here :

    https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/quarterlyalcoholspecificdeathsinenglandandwales/2001to2019registrationsandquarter1jantomartoquarter4octtodec2020provisionalregistrations

    12 min

About Ram Arora Podcasts Library

From the publisher's feed

Mutliple podcasts ranging from my interviews with the BBC to those pertaining to general medicine and primary care. I have a specialist interest in addictions and have a specific focus on how it…

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