March 11, 2026

Regenerative Therapy Using Exosomes w/ Caleb Granger

1 hour 2 minutes

Caleb Granger explains that mesenchymal stem cells should be called medicinal signaling cells, as they secrete healing signals through exosomes, which are tiny particles that facilitate cell communication. Caleb highlights the benefits of exosomes in regenerative therapies, such as treating post-oncological prostatectomy erectile dysfunction and muscle wasting during chemotherapy. He also discusses the limitations of stem cell transplants, noting that the body often flushes out transplanted cells and that PRP therapy, which involves concentrating native growth factors, can create inflammation but lacks sufficient healing signals.

Key takeaways

Exosomes are more effective than stem cells for regenerative medicine because they contain healing signals without triggering inflammatory responses

Placental and umbilical mesenchymal stem cell exosomes are the most potent sources of regenerative signals

As we age, our regenerative capacity decreases (from ~150-200 million stem cells as teenagers to ~30-50 million by age 50)

Exosomes can help regenerate tissue, reduce inflammation, and treat various conditions including orthopedic injuries, neuropathies, and organ dysfunction

Unlike traditional pharmaceuticals, exosomes help the body heal itself rather than masking symptoms

Exosomes are WADA, USADA, NCAA, and Olympic compliant for athletes

To learn more, visit theapexmedical.com and follow on Instagram @apexregenerative

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Production credit: Social Media Cowboys

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By Jerry Snider

88 ratings