The unbreakable bond between man and canine was put to the test like never before in the winter of 1925.  An unbelievable journey, over the nation's harshest terrains, in unimaginable conditions, with life and death of an entire village in the balance.  Against all odds, these specialized teams must deliver the serum, that only they can, to a remote Alaskan coastal town.  But can they make it before time runs out?  And how will their sacrifice lead to the greatest race that man and animal share?