Delphine Douillet est Professeure en médecine d'urgence au CHU d'Anger, experte des maladies thrombo-emboliques. Françoix-Xavier Ageron l'a rencontrée pour parler recherche, anticoagulation prophylactique et TRiP(cast) score, traumatisme crânien et concentré de complexe prothrombinique (PCC), andexanet, ou encore embolie pulmonaire. Une interview d'experte passionnante à ne pas manquer!

Références du podcast :

Douillet D, Penaloza A, Viglino D, et al. Targeted prophylactic anticoagulation based on the TRiP(cast) score in patients with lower limb immobilisation: a multicentre, stepped wedge, randomised implementation trial. Lancet. 2024 Mar 16;403(10431):1051-1060.

Connolly SJ, Sharma M, Cohen AT, et al. Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. N Engl J Med. 2024 May 16;390(19):1745-1755.

Douillet D, Godon A, Rousseau G, et al. Anticoagulant management in Emergency settings: 2024 guidelines from the French Society of Emergency Medicine (SFMU), the French Society of Anaesthesia and Intensive Care Medicine (SFAR), the French Society of Thrombosis and Haemostasis (SFTH) and the French Working Group on Perioperative Haemostasis (GIHP), endorsed by the French Neurovascular Society. Anaesth Crit Care Pain Med. 2025 Sep;44(5):101584.

Douillet D, Tazarourte K, Dehours E, et al. Systematic vitamin K antagonist reversal with prothrombin complex concentrate in patients with mild traumatic brain injury: randomized controlled trial. Eur J Emerg Med. 2025 Jun 1;32(3):180-187.