Most people think longevity is about living longer.
Dr. Jack Kreindler thinks that's exactly where we've gone wrong.
The longevity industry has never been bigger. Every week there's a new supplement, a new biomarker, a new biohack, or a new promise that you can slow aging.
But after more than 25 years working with elite athletes, founders, CEOs and patients facing life-threatening disease, Jack has reached a very different conclusion.
The goal isn't to live longer. It's to stay fully alive for as long as possible.
In this episode of Return on Health, hosts Niko Hems and Miguel Medina sit down with one of the world's leading physicians in preventive medicine and human performance to separate evidence from hype.
We explore why Jack has become one of the biggest critics of the word longevity, what he really thinks about Bryan Johnson and David Sinclair, whether NAD boosters actually make sense, and why purpose, relationships and resilience may be more powerful than the latest biohack.
━━━━━👤 ABOUT THE GUEST━━━━━
Dr. Jack Kreindler is a physician, physiologist and entrepreneur specializing in preventive medicine, human performance and healthy aging.
He is the Founder & CEO of WellFounded and previously founded the Centre for Health and Human Performance (CHHP) in London, where he pioneered a model combining elite sports science with clinical medicine.
Over the past two decades, he's worked with Olympic athletes, military personnel, founders, CEOs and patients with complex medical conditions - helping them maximize health, performance and resilience rather than simply adding years to life.
━━━━━🎙️ ABOUT THE HOSTS━━━━━━
Niko Hems
Niko Hems is a longevity expert and Head of Growth at YEARS, a company building a longitudinal, multi-modal health dataset to make prevention personal and data-driven.
Miguel Medina
Miguel Medina is co-host of Return on Health, a podcast built on a simple idea: a system always produces the outcomes it's incentivized to produce - so if we want better health outcomes, we need better incentives.
━━━━━━CHAPTERS━━━━━━
00:00 Why Jack Rejects the Word "Longevity"
01:33 What People Are Really Asking For
03:29 Healthspan vs. Lifespan
08:42 The Pillars That Actually Matter
12:02 What Happens Inside a Longevity Clinic
17:56 The Biomarkers Worth Paying Attention To
19:45 Why Human Connection Might Be the Ultimate Biomarker
28:25 Environmental Toxins & Modern Living
32:50 Are Toxins Really Making Us Sick?
36:14 Bryan Johnson, David Sinclair & Longevity Escape Velocity
40:03 What Founders Can Learn From Elite Performers
44:06 Burnout, Stress & High Performance
47:27 Can We Really Make 90 the New 60?
48:30 The Longevity Supplement Jack Would Never Take
49:40 The Supplements He Actually Recommends
51:15 Will AI Replace Doctors?
52:51 The Biggest Problem With Modern Healthcare
━━━━━💡 KEY QUESTIONS ANSWERED━━━
• Is the longevity industry focusing on the wrong goal?
• Can you actually extend your lifespan - or just your healthspan?• Are expensive longevity supplements worth the money?
• What does Jack really think about Bryan Johnson's Blueprint?
• Which supplements have the strongest evidence today?
• Why is VO₂ Max one of the most powerful predictors of long-term health?
• Are environmental toxins a bigger problem than we realize?
• Can AI become a better doctor than humans?
• Why might relationships, purpose and meaning outperform the latest biohacks?
• What would Jack change about modern healthcare if he could?
Connect with Jack
🌐 WellFoundedhttps://wellfounded.health
🏥 Centre for Health and Human Performance (CHHP)https://chhp.com
💼 LinkedInhttps://www.linkedin.com/in/jackkreindler/
