How do the experts balance organ preservation, oncologic control, and emerging therapies in both localized and metastatic cases of penile cancer? This episode of BackTable Tumor Board focuses on penile cancer diagnosis and treatment, featuring urologic oncologist Dr. Charles Peyton (UAB), radiation oncologist Dr. Juanita Crook (UBC), and medical oncologist Dr. Andrea Apolo (NCI).

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This podcast is supported by:
Ferring Pharmaceuticals

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SYNPOSIS

This session covers case studies ranging from localized to advanced penile cancer, diagnostic practices, imaging preferences (MRI vs. CT), and treatment options, including surgery, brachytherapy, chemoradiation, and neoadjuvant chemotherapy. The multidisciplinary team highlights the complexities of treating this rare cancer, underscores the importance of physical exams, and stresses the necessity of personalized treatment plans. They also delve into the challenges of managing metastatic stages, potential salvage therapies, and the importance of clinical trials in enhancing treatment efficacy. The doctors also emphasize the potential of immunotherapy and chemotherapy combinations for metastatic disease.

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TIMESTAMPS

00:00 - Introduction
02:23 - Imaging Preferences
03:29 - Biopsy vs Immediate Surgery
06:04 - Lymph Node Dissection vs Radiation
13:48 - Brachytherapy Techniques and Case Study
23:21 - Challenges in Advanced Penile Cancer
27:03 - Chemotherapy and Chemoradiation
30:15 - InPACT Trial
37:12 - Salvage Therapies and Exploring New Treatment Frontiers
44:25 - Support and Awareness for Penile Cancer
51:29 - Final Thoughts

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RESOURCES

Society of Urologic Oncology
https://suonet.org/home.aspx