With so many treatment modalities for upper tract urothelial carcinoma, how does new evidence inform optimal care? In this episode of BackTable Tumor Board, urologic oncologist Dr. Nirmish Singla (Johns Hopkins), medical oncologist Dr. Jeannie Hoffman-Censits (Johns Hopkins), and urologic oncologist Dr. Bogdana Schmidt discuss treatment and diagnosis of upper tract urothelial carcinoma (UTUC).

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This podcast is supported by:

This podcast is supported by:

⁠⁠Ferring Pharmaceuticals⁠

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SYNPOSIS

The discussion covers real-world UTUC cases, highlighting diagnostic challenges, treatment options, and evidence-based management strategies. They address scenarios ranging from localized to advanced UTUC, the role of systemic therapies, perioperative treatments, and the potential for novel approaches with immune checkpoint inhibitors. The episode underscores the evolving landscape of UTUC treatment and the importance of clinical trials and emerging biomarkers in improving patient outcomes.

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TIMESTAMPS

00:00 - Introduction
02:49 - Case Study 1: 66-Year-Old Male with UTUC
11:19 - Case Study 2: 73-Year-Old Male with High-Grade Urothelial Carcinoma
28:11 - Intravesical Chemotherapy Protocols
30:44 - Case Study 3: 57-Year-Old Male with Recurrent Urothelial Cancer
41:25 Clinical Trials and Emerging Treatments
45:40 Case Study: 55-Year-Old Female with Bulky Lymphadenopathy
56:45 Concluding Remarks and Future Directions

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RESOURCES

Society of Urologic Oncology
https://suonet.org/home.aspx

What if the key to better cancer outcomes lies not just in surgery or chemotherapy, but also in mindfulness, movement, and diet? In this episode of the BackTable Tumor Board, host Dr. Aditya Bagrodia interviews urologic oncologist Dr. Viraj Master, Professor of Urology at Emory University, about his role in developing the integrative oncology and survivorship service line at Winship Cancer Institute.

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This podcast is supported by:

This podcast is supported by:

⁠⁠Ferring Pharmaceuticals⁠

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SYNPOSIS

They discuss the evidence-based use of complementary therapies alongside conventional cancer treatments, touching on various integrative methods including diet, exercise, mindfulness, acupuncture, yoga, and supplements. Dr. Master emphasizes the importance of physicians being open to these practices and understanding their potential benefits for improving patient outcomes and quality of life, even in highly acute cases like muscle-invasive bladder cancer. The conversation covers the importance of honesty and understanding across patient journeys–from initial diagnosis to survivorship–highlighting the value of holistic approaches in cancer care.

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TIMESTAMPS

00:00 - Integrative Oncology: Definitions and Basics
06:28 - Exercise and Its Impact on Cancer Treatment
08:12 - Physician Perspectives on Complementary Medicine
20:58 - Acupuncture and Acupressure in Cancer Care
25:28 - Practical Implementation of Integrative Approaches
31:30 - Supplements and Immuno Nutrition
36:25 - Cannabis, CBD, and Ayurveda in Cancer Care
44:39 - Conclusion and Final Thoughts

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RESOURCES

Society of Urologic Oncology
https://suonet.org/home.aspx

How can pediatric and adult urologists team up to tackle complex cancer cases? In this episode of the BackTable Tumor Board, host Dr. Amanda Buchanan, Division Chief of Pediatric Urology at the University of Kentucky, is joined by her colleagues Dr. Patrick Hensley, an adult urologic oncologist, and Dave Rodeberg, Division Chief of Pediatric Surgery. Their discussion centers around the importance of professional collaboration in urologic oncology care in order to improve patient outcomes.

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This podcast is supported by:

This podcast is supported by:

⁠⁠Ferring Pharmaceuticals⁠

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SYNPOSIS

The urologists discuss topics such as the experiences and benefits of interdisciplinary collaboration in complex cases and the role of pediatric urologists in treating adolescent and young adult patients. They also provide insights into the Children's Oncology Group (COG) studies and their intersections with adult oncology research. The episode concludes with practical advice for other institutions aiming to improve collaborative efforts between pediatric and adult urology departments.

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TIMESTAMPS

00:00 - Importance of Collaboration in Urologic Oncology
05:38 - Challenges in Multidisciplinary Collaboration
08:30 - Pediatric Urologists’ Role in Testicular Cancer
11:05 - Clinical Trials and Research Collaborations
14:21 - Navigating COG and Adult Oncology Groups
19:03 - Collaborative Approach to Kidney Tumors
29:31 - Resident Education and Collaboration
35:22 - Final Thoughts

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RESOURCES

Society of Urologic Oncology:
https://suonet.org/home.aspx

Children’s Oncology Group
https://www.childrensoncologygroup.org/

How can urologists and radiologists work together to improve kidney cancer treatment? In this episode, BackTable Tumor Board brings together Dr. Jason Abel (Professor of Urology and Radiology at the University of Wisconsin), Dr. Louis Hinshaw (Section Chief of Abdominal Imaging Intervention at the University of Wisconsin), and Dr. Ruchika Talwar (Assistant Professor of Urologic Oncology at Vanderbilt) for a multidisciplinary conversation regarding the treatment of renal tumors.

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This podcast is supported by:

This podcast is supported by:

⁠⁠Ferring Pharmaceuticals⁠

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SYNPOSIS

Their discussion covers the history and benefits of collaboration between urology and interventional radiology (IR), advances in image-guided procedural technologies, and the importance of teamwork in improving patient outcomes. The episode also considers the encouraging, but limited data in IR treatments such as microwave ablation and discusses the lasting role for surgery. Finally, Dr. Abel and Dr. Hinshaw share their experiences in establishing a successful interdisciplinary kidney cancer program. Ultimately, they conclude that the future of renal tumor treatment lies not in silos, but in collaboration.

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TIMESTAMPS

00:00 - Multidisciplinary Collaboration in Renal Tumor Treatment
05:59 - Advancements in Ablation Techniques: From Cryoablation to Microwave
10:13 - Ablation vs. Surgery: Patient Selection and Clinical Decision Making
14:00 - Technical Considerations and Complications in Ablation Procedures
24:19 - Patient Experience and Recovery Post-Ablation
36:17 - Importance of Teamwork in Modern Medicine

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RESOURCES

Society of Urologic Oncology
https://suonet.org/home.aspx

What does it take to deliver truly personalized, multidisciplinary care in testicular cancer? Get an inside look in this episode of BackTable Tumor Board, where renowned testicular cancer experts Dr. Nabil Adra and Dr. Richard Matulewicz join host Dr. Aditya Bagrodia for a virtual tumor board session on the nuanced management of germ cell tumors.

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This podcast is supported by:

⁠Ferring Pharmaceuticals

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SYNPOSIS

The expert panel uses specific patient cases to review their decision-making processes on the use of surgery, chemotherapy, and radiation. They highlight the importance of a multidisciplinary approach, particularly for advanced disease and challenging surgical scenarios. The episode reviews patient-specific factors, standard treatment protocols, post-treatment surveillance, and the latest research. This episode also highlights the benefits of personalized cancer care.

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TIMESTAMPS

00:00 - Case Presentation: 23-Year-Old Male with Testicular Mass
09:53 - Surveillance vs. Adjuvant Therapy Debate
13:53 - Recurrence, Comprehensive Staging, and Next Steps
23:09 - Case Study: 44-Year-Old with Mixed Non-Seminoma Germ Cell Tumor
27:47 - Surveillance and Surgery Recommendations
28:11 - Case Study: 17-Year-Old with Developmental Delay and Cancer
30:10 - Chemotherapy, Surgical Timing, and Prognosis
44:58 - Case Study: 21-Year-Old with Scrotal Swelling
47:12 - Surgical Considerations and Multidisciplinary Approach

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RESOURCES

Society of Urologic Oncology
https://suonet.org/home.aspx

There are now multiple phase 3 studies on combination transarterial chemoembolization (TACE) and immunotherapy showing a significant benefit over TACE alone. How do these findings change the hepatocellular carcinoma (HCC) treatment algorithm? In this multidisciplinary episode of the BackTable Podcast, Dr. Richard Finn (Medical Oncologist at UCLA) and Dr. Julius Chapiro (Interventional Radiologist at Yale University) join host Dr. Chris Beck to discuss immunotherapy, TACE, emerging trends in HCC treatment, and the future of the field.
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This podcast is supported by an educational grant from Guerbet.
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SYNPOSIS
The doctors highlight the importance of high quality clinical data and the pivotal studies shaping current best practices. They explore the role of the different players on the multidisciplinary team and compare the oncologic and radiologic perspectives. Additionally, they discuss the synergy between TACE and immunotherapy, the criteria for selecting appropriate treatments, and the ongoing need for research and collaboration.
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TIMESTAMPS
00:00 - Introduction
03:35 - HCC from an Oncologic Perspective
05:33 - Radiological Perspective on Liver Cancer
06:50 - Referral Patterns and Organizing a Multidisciplinary Approach
18:01 - Explaining TACE and Variations in the Procedure
27:27 - Choosing the Right Procedure for HCC
36:13 - Making a Decision on Medical Treatment Candidacy
42:23 - Importance of Data Driven HCC Treatment, Practical Insights, and Studies to Know
55:30 - Planning an Approach for a TACE Procedure
01:02:26 - Final Thoughts and Future Prospects in Liver Cancer Treatment
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RESOURCES
Barcelona Staging System:
https://www.ncbi.nlm.nih.gov/books/NBK569796/table/Ch3-t0001/
TRACE Trial:
https://pubs.rsna.org/doi/full/10.1148/radiol.211806
PREMIERE Trial:
https://www.gastrojournal.org/article/S0016-5085(16)34971-X/fulltext
EMERALD-1 Trial:
https://ascopubs.org/doi/10.1200/JCO.2024.42.3_suppl.LBA432
LEAP O12 Study:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02575-3/abstract

Medical, surgical, radiation, and interventional oncology all play vital roles in delivering care to patients battling liver cancer. How do we optimize outcomes when so many specialties have something to offer the same patient? The answer is collaborative oncology. Dr. Robert Martin (Director of Surgical Oncology, University of Louisville) and pioneer in liver-directed therapies, joins host Dr. Sabeen Dhand to discuss a collaborative approach to oncology and recent advances in locoregional therapy.

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This podcast is supported by:

RADPAD® Radiation Protection

https://www.radpad.com/

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SYNPOSIS

Dr. Martin discusses the importance of a growth mindset in advancing medical techniques and fostering collaborations between specialists. He then shares insights into minimally invasive procedures, such as microwave ablation and irreversible electroporation (IRE). The doctors also touch on the evolution of liver cancer treatments, emphasizing the significance of clinical trials on the horizon. To conclude, Dr. Martin encourages young professionals in surgery and interventional radiology to stay open-minded, be life-long learners, and find synergistic ways to integrate new technologies into patient care.

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TIMESTAMPS

00:00 - Introduction

02:31 - Dr. Martin’s Background and Career Path

06:18 - Evolution of Liver Directed Therapies

10:12 - Collaboration Between Specialties

18:34 - Clinical Trials and Emerging Therapies

36:08 - Advice for Young Professionals

39:15 - Conclusion

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RESOURCES

Radioembolization Oncology Trial Utilizing Transarterial Eye90 (ROUTE 90) for the Treatment of HCC:

https://clinicaltrials.gov/study/NCT05953337?term=NCT05953337&rank=1

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS (INJECTABL-1):

https://clinicaltrials.gov/study/NCT05688280

Immunophotonics, CIRSE, and Next Research Announce Innovative Phase 2/3 Clinical Trial: INJECTABL-3:

https://immunophotonics.com/news/immunophotonics-cirse-and-next-research-announce-innovative-phase-2-3-clinical-trial-injectabl-3/

Do you ever wish you could be a fly on the wall at a tumor board meeting? In this episode of BackTable, we’re excited to give you an insider’s view of the real case discussions that take place during hepatocellular carcinoma (HCC) tumor boards. Host Dr. Zach Berman sits down with a multidisciplinary team, including Drs. Adam Burgoyne (medical oncologist), Heather Patton (hepatologist), Siddharth Padia (interventional radiologist), and Gabriel Schnickel (transplant and hepatobiliary surgeon).

Physicians, nurses, nurse practitioners, and physician assistants can follow this link to earn CME / CE credits for completing an accredited learning activity related to this discussion:

https://www.cmeuniversity.com/course/take/125743

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This podcast is supported by an educational grant from AstraZeneca Pharmaceuticals and Boston Scientific.

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SYNPOSIS

The team walks through a range of diverse HCC cases, reviewing patient histories, imaging, and treatment options. They cover eight cases in total, each featuring patients with varying treatment histories, comorbidities, liver function, and lesion characteristics. For the full educational experience, we recommend watching the video format on our YouTube channel.

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TIMESTAMPS

00:00 - Introduction

00:47 - Case 1: Small Lesion in a Young Patient

05:01 - Case 2: Moderate Sized Lesion in an Older Patient

11:10 - Case 3: Multifocal HCC with Dominant Lesion

21:09 - Case 4: Dominant Lesion with Portal Hypertension

32:08 - Case 5: Ruptured Solitary Lesion

34:34 - Case 6: Rupture with Multifocal Lesions

44:08 - Case 7: Portal Vein Invasion

52:12 - Case 8: Metastatic HCC After Transplant

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RESOURCES

CME Accreditation Information:

https://f7cae4ec-b69e-490d-9e0f-19b16a6f146d.usrfiles.com/ugd/f7cae4_a7c37ea3cd1b4d3fa53d5edf8dfe255b.pdf

Are you seeking to build your reputation and patient base within interventional oncology? In this episode, host Dr. Zachary Berman interviews Dr. Siddarth Padia, Dr. Tyler Sandow, Dr. Kavi Krishnasamy, and Dr. Kevin Burns about their journeys into interventional oncology (IO) and their experiences providing care in different practice settings.

Physicians, nurses, nurse practitioners, and physician assistants can follow this link to earn CME / CE credits for completing an accredited learning activity related to this discussion:

https://www.cmeuniversity.com/course/take/125742

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This podcast is supported by an educational grant from AstraZeneca Pharmaceuticals and Boston Scientific.

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SYNPOSIS

The doctors begin by discussing how they became interested in interventional oncology, with most of them recognizing opportunities to address unmet needs in the field. Each guest shares insights on the timelines and challenges involved in starting their IO practices, which vary significantly today. For instance, telehealth clinics are particularly viable in private practice IO, thanks to conferencing software and virtual translators. Hybrid care models, which combine in-person and remote consultations, can help overcome patient-level barriers such as time and transportation. The panel also emphasizes how increased clinic availability can significantly drive growth in procedural volume. Finally, they offer advice for starting an IO practice, including the importance of having clinic support staff, building strong relationships with referring physicians, and staying up to date with new technologies.

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TIMESTAMPS

00:00 - Introduction

05:38 - Balancing Career Interests and Expectations

07:10 - Building an Interventional Oncology Practice

13:42 - Gaining Trust from Referring Physicians

17:33 - Importance of Open Communication

19:19 - Comparing Clinic Settings

26:01 - Essential Components of a Clinic

33:28 - Narrowing Your Interventional Practice

40:09 - Introducing New Technology

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RESOURCES

CME Accreditation Information:

https://f7cae4ec-b69e-490d-9e0f-19b16a6f146d.usrfiles.com/ugd/f7cae4_a7c37ea3cd1b4d3fa53d5edf8dfe255b.pdf

Is surgery truly the "cure" for hepatocellular carcinoma (HCC), and when is it a viable option? In this episode, Dr. Sabeen Dhand leads a roundtable discussion with interventional radiologist Dr. Siddharth Padia and transplant/hepatobiliary surgeons Dr. John Seal and Dr. Gabriel Schnickel, delving into the complexities of surgical treatments for HCC and the evolving landscape of liver resection and transplantation.

Physicians, nurses, nurse practitioners, and physician assistants can follow this link to earn CME / CE credits for completing an accredited learning activity related to this discussion:

https://www.cmeuniversity.com/course/take/125741

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This podcast is supported by an educational grant from AstraZeneca Pharmaceuticals and Boston Scientific.

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SYNPOSIS

The doctors begin by discussing how they manage patient expectations regarding both palliative and curative treatments, highlighting the risk of recurrent HCC as a new lesion. They then outline key factors that influence their recommendations for liver transplant versus resection, such as the extent of underlying liver disease, the function of the future liver remnant, body habitus, overall health, and organ availability. The surgeons also review various surgical approaches to liver resection and recent advancements in liver transplantation, including living donor transplants and the ability to refer patients for downstaging procedures.

Dr. Padia explains the original role of Y90 as a bridging treatment to downstage tumors and promote hypertrophy in the non-diseased liver segments, preparing the organ for surgical resection. However, Y90 treatment can also lead to the formation of adhesions, which may complicate future surgeries. Finally, the doctors discuss strategies to improve care coordination between community physicians and transplant centers to optimize patient outcomes.

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TIMESTAMPS

00:00 - Curative vs. Palliative Treatment

04:03 - Choosing Between Transplantation and Resection

05:47 - Liver Resection Types

07:27 - Bridging Role of Y90

12:14 - Evolving Landscape of Liver Transplantation

20:59 - Patient Counseling in Minimally Invasive Procedures

28:40 - Considerations for Surgery After Y90

33:32 - Coordination Between Specialists

40:08 - Immunotherapy as a Bridge to Transplant

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RESOURCES

CME Accreditation Information:

https://f7cae4ec-b69e-490d-9e0f-19b16a6f146d.usrfiles.com/ugd/f7cae4_a7c37ea3cd1b4d3fa53d5edf8dfe255b.pdf