Beginning in 2019, the Regional Initiative to Accelerate Carbon Capture, Utilization, and Storage (CCUS) Deployment is supporting the Office of Fossil Energy and Carbon Management’s (FECM) mission to help the United States meet its need for secure, affordable, and environmentally sound fossil energy supplies. This builds upon advancements made by the Regional Carbon Sequestration Partnership (RCSP) Initiative by identifying and addressing challenges to the widespread, commercial deployment of CCUS. There are four individual Regional Initiatives that gather and analyze information for their respective regions, work with existing and future demonstration projects, and coordinate certain efforts related to past and current field projects such as the Department of Energy’s CarbonSAFE. By leveraging the strengths of the new Regional Initiatives, it will be possible to identify and promote potential carbon transportation/utilization/storage projects that will help meet goals for a future net-zero carbon economy. The four Regional Initiatives have been established to further the mission of the U.S. Department of Energy/National Energy Technology Laboratory Carbon Storage Program.