Join Drs Anne Cross and Rob Motl as they discuss how new data and clinical insights are reshaping how exercise helps people with MS.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002604. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Intrathecal Baclofen for Multiple Sclerosis–Related Spasticity: A Twenty-Year Experience https://pubmed.ncbi.nlm.nih.gov/30366276/

Prevalence of Depression and Anxiety in Multiple Sclerosis: A Systematic Review and Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/28017241/

Study Protocol: Exercise Training for Treating Major Depressive Disorder in Multiple Sclerosis https://pubmed.ncbi.nlm.nih.gov/38632556/

CDMRP Multiple Sclerosis https://cdmrp.health.mil/msrp/default

Effect of Exercise on Depressive Symptoms in Adults With Neurologic Disorders: A Systematic Review and Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/25596001/

National MS Society Exercising With MS https://www.nationalmssociety.org/managing-ms/living-with-ms/diet-exercise-and-healthy-behaviors/exercise

Moderators of Exercise Effects on Depressive Symptoms in Multiple Sclerosis: A Meta-regression https://pubmed.ncbi.nlm.nih.gov/28602542/

Physical Activity, Fitness, and Gray Matter Volume https://pubmed.ncbi.nlm.nih.gov/24952993/

Exercise-Mediated Neurogenesis in the Hippocampus via BDNF https://pubmed.ncbi.nlm.nih.gov/29467613/

Integrative CNS Plasticity With Exercise in MS: The PRIMERS (PRocessing, Integration of Multisensory Exercise-Related Stimuli) Conceptual Framework https://pubmed.ncbi.nlm.nih.gov/30205784/

Effects of Physical Exercise on Plasma Brain-Derived Neurotrophic Factor in Neurodegenerative Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://pubmed.ncbi.nlm.nih.gov/34087277/

Multimodal Enhancement of Remyelination by Exercise With a Pivotal Role for Oligodendroglial PGC1α https://pubmed.ncbi.nlm.nih.gov/30232000/

Cognitive Rehabilitation and Aerobic Exercise for Cognitive Impairment in People With Progressive Multiple Sclerosis (CogEx): A Randomised, Blinded, Sham-Controlled Trial https://pubmed.ncbi.nlm.nih.gov/37739574/