In Part 2 of this series, we move from the macro terrain into the cellular layer—where disease is ultimately decided.
Host Shaughn Jenson, Registered Advanced Ayurvedic Practitioner, is joined again by Dr. Deepu Mirchandani, retired medical oncologist and molecular pathobiology specialist, where we explore the concept of cellular fidelity: the precision with which a cell maintains its identity, regulates its behavior, and determines its fate.
This episode bridges modern molecular biology with Ayurvedic theory to examine how cells make critical decisions—whether to repair, continue, or undergo programmed removal.
We discuss:
- DNA replication and repair systems, including the role of topoisomerase and repair enzymes.
- The p53 pathway as the “guardian of the genome” and its role in apoptosis.
-The regulatory mechanisms of epigenetics—DNA methylation, histone modification, and chromatin remodeling.
-The balance between survival and death signaling within the cell
-How environmental factors influence gene expression and long-term disease development
From an Ayurvedic perspective, these processes are understood through the framework of agni (transformative intelligence), tejas (discriminative clarity), and tamas (inertia or resistance to change).
Health, at the cellular level, is not the absence of damage—it is the precision of repair, regulation, and removal.
This episode offers a detailed synthesis of how both systems describe the same fundamental processes from different lenses.
In Part 3, we will explore the next layer of protection: immune surveillance.
Samya Ayurveda Podcast — exploring the intersection of traditional knowledge and modern science.
Produced in collaboration with the Ayurveda College of British Columbia.
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