Host Maureen A. Madden, DNP, RN, CPNP-AC, CCRN, FCCM, FAAN, is joined by Dr. Lakshmi Raman, MD, to explore critical insights into pediatric ECMO, addressing neurological complications and their potential mitigation strategies and other topics associate with the article "Early Changes in Arterial Partial Pressure of Carbon Dioxide and Blood Pressure After Starting Extracorporeal Membrane Oxygenation in Children: Extracorporeal Life Support Organization Database Study of Neurologic Complications" (Pedtr Crit Care Med. July 2023; 24(7):541-550). Dr. Raman is Professor of Pediatrics and Medical Director of ECMO at the University of Texas Southwestern Medical Center and Children's Medical Center in Dallas, Texas.