Margaret Parker, MD, MCCM, speaks with Ericka L. Fink, MD, MS, about the PANGEA study (Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment), published in the April 2017 issue of Pediatric Critical Care Medicine.

Sean P. Kane, PharmD, BCPS, speaks with Joshua Trob, MD about continuous renal replacement therapy. In the episode, the indications, timing of initiation, and intensity of renal replacement therapy are discussed.

Todd Fraser, MD, speaks with Jenny Tcharmtchi, BSN, RN, CCRN, about the article, "Family Experience in the PICU," published in Critical Connections, the Society of Critical Care Medicine's newsletter.

Dr. Ludwig Lin, MD, speaks with Christina Jones, PhD, RN, about the ICU Patient Diary Network. Dr. Jones discusses the widespread adoption of ICU diaries in the United Kingdom, various models that institutions are using, and the overall positive impact that implementation has had on patients, families, and providers.

Sean P. Kane, PharmD, BCPS, speaks with Karen Berger, PharmD, BCPS, BCCCP about refractory status epilepticus. In the episode, the use of continuous sedatives is discussed for refractory epilepticus with a focus on the novel use of ketamine in super-refractory status epilepticus patients.

Margaret Parker, MD, MCCM, speaks with John J. Marini, MD, about the Congress session Clinician Pro/Con: Paralysis and Proning in ARDS, which was presented at the 45th Critical Care Congress in Orlando, Florida.

Sean P. Kane, PharmD, BCPS, speaks with Elliott Cohen, MD about extracorporeal membrane oxygenation (ECMO). In the episode, the basics of Veno-Arterial (VA) and Veno-Venous (VV) ECMO are outlined and the indications of ECMO therapy are discussed.

Sean P. Kane, PharmD, BCPS, speaks with Scott T. Benken, PharmD, BCPS-AQ Cardiology about vasopressor selection in septic shock. In the episode, each vasopressor agent is discussed individually regarding its receptor profile, adverse effect profile, and the comparative clinical evidence supporting its use in this patient population.

Sean P. Kane, PharmD, BCPS, speaks with Nadia Awad, PharmD, BCPS about Rumack-Matthew nomogram and acetaminophen toxicity. In the episode, the toxidrome of acetaminophen overdose is outlined and the nuances (including clinical practice pearls) are discussed regarding the nomogram used to decide whether N-acetylcysteine is warranted for acetaminophen toxicity.

Ludwig Lin, MD, speaks with Brenda Pun, DNP, RN, ACNP, about the ICU Liberation ABCDEF Bundle Improvement Collaborative. Dr. Pun reflects upon Collaborative work, including origins and logistics of the project, team training and resource-sharing, and the importance of the interprofessional care model, as well as successes, challenges, and barriers to bundle implementation.