Dr. Ludwig Lin, MD, speaks with Christina Jones, PhD, RN, about the ICU Patient Diary Network. Dr. Jones discusses the widespread adoption of ICU diaries in the United Kingdom, various models that institutions are using, and the overall positive impact that implementation has had on patients, families, and providers.

Sean P. Kane, PharmD, BCPS, speaks with Karen Berger, PharmD, BCPS, BCCCP about refractory status epilepticus. In the episode, the use of continuous sedatives is discussed for refractory epilepticus with a focus on the novel use of ketamine in super-refractory status epilepticus patients.

Margaret Parker, MD, MCCM, speaks with John J. Marini, MD, about the Congress session Clinician Pro/Con: Paralysis and Proning in ARDS, which was presented at the 45th Critical Care Congress in Orlando, Florida.

Sean P. Kane, PharmD, BCPS, speaks with Elliott Cohen, MD about extracorporeal membrane oxygenation (ECMO). In the episode, the basics of Veno-Arterial (VA) and Veno-Venous (VV) ECMO are outlined and the indications of ECMO therapy are discussed.

Sean P. Kane, PharmD, BCPS, speaks with Scott T. Benken, PharmD, BCPS-AQ Cardiology about vasopressor selection in septic shock. In the episode, each vasopressor agent is discussed individually regarding its receptor profile, adverse effect profile, and the comparative clinical evidence supporting its use in this patient population.

Sean P. Kane, PharmD, BCPS, speaks with Nadia Awad, PharmD, BCPS about Rumack-Matthew nomogram and acetaminophen toxicity. In the episode, the toxidrome of acetaminophen overdose is outlined and the nuances (including clinical practice pearls) are discussed regarding the nomogram used to decide whether N-acetylcysteine is warranted for acetaminophen toxicity.

Ludwig Lin, MD, speaks with Brenda Pun, DNP, RN, ACNP, about the ICU Liberation ABCDEF Bundle Improvement Collaborative. Dr. Pun reflects upon Collaborative work, including origins and logistics of the project, team training and resource-sharing, and the importance of the interprofessional care model, as well as successes, challenges, and barriers to bundle implementation.

Sean P. Kane, PharmD, BCPS, speaks with Joseph Muench, PharmD, BCPS about airway pharmacology. In the episode, the most common sedatives and paralytics for rapid sequence intubation are discussed, including concepts regarding dosing, adverse effects, onset and duration of effect, and clinical pearls.

Sean P. Kane, PharmD, BCPS, speaks with Frank Paloucek, PharmD, DABAT about the use of activated charcoal in the overdose patient. In the episode, nuances of activated charcoal including dosing, dosage forms, administration, and efficacy are discussed.

Ranjit Deshpande, MD, speaks with Patrick Kochanek, MD, MCCM, about his plenary talk at the 46th Critical Care Congress in Honolulu, Hawaii, entitled The Brain and Hypothermia: From Aristotle to Targeted Temperature Management, the Good Stuff Keeps Coming Back.