Science & Chill

In this clip from episode 41 of the Science & Chill podcast (Dr. Kieran Clarke and Brian McMahon from deltaG Ketones), Dr. Clarke discusses the recent literature on exogenous ketones and exercise performance, as well as potential applications for exogenous ketones for recovery and preventing overtraining.

 

Listen to the full episode HERE.

In this episode of the Science & Chill podcast, I interview Dr. Kieran Clarke and Brian McMahon of T delta S, a company who sells deltaG ketones, an exogenous ketone ester.

Dr. Kieran Clarke is a legend in the ketone world. Born in Adelaide, South Australia, Kieran Clarke studied for her undergraduate BSc (Hons) in Biological Sciences at Flinders University. She obtained her PhD in Biochemistry at the University of Queensland before taking a post-doctoral fellowship at Harvard University Medical School Nuclear Magnetic Resonance Laboratory between 1985 and 1989. She has over 25 years research experience in magnetic resonance (MR) imaging and spectroscopy to non-invasively measure human cardiac, brain and skeletal muscle function and energy metabolism.

We are also joined in this episode by Brian McMahon. Brian is the Chief of Staff at T delta S, and it was awesome to have him on the interview to give his perspective on the market for exogenous ketone ester, what makes T delta S special among the many available ketone products, and how he got into this area of health and performance.

Even if you aren’t fully up to speed on the biochemistry of ketones, I think you will enjoy this episode. Dr. Clarke and Brian do a fantastic job of describing the science of ketosis and their product, and even though I had some prior knowledge in this area, I came away from this interview with much more knowledge and interest in ketone esters than I previously had.

Before I go, I would like to mention that there are several ways that you can support this podcast if you have the means to do so. The first and best way it to become a supporter on Patreon, where you can pledge a monthly donation of your choosing. Thanks so much to all the current supporters who make this podcast possible.

You can also support this podcast by making a one-time donation through PayPal. You can find a link in the show notes to show your support in this way. Finally, you can support my work by purchasing product sponsors of the show. Right now, we are supported by LMNT electrolyte drink mix, a tasty and effective electrolyte supplement that I use multiple times per day to fuel and recover from workouts. I promise that you’ll love this product and encourage you to try some for yourself. You can go to drinkLMNT.com/scienceandchill to claim a free sample pack if you haven’t done so already, but you can also use the link to replenish your stock of salt.

Without further ado, please enjoy my conversation with Dr. Kieran Clarke and Brian McMahon.

Links

deltaG Ketones

Follow deltaG Ketones on Twitter (@deltaGKetones) and Instagram (@deltag.ketones)

Link to peer-reviewed literature on delta G

Support Science & Chill on Patreon

Make a one-time donation to the podcast on PayPal

Subscribe to my weekly email newsletter

Check out our sponsor: LMNT electrolyte drink mix!

 

Check out the complete episode shownotes, including the transcript, on the episode web page!

My guest today is Mark Huston. Mark is a doctoral candidate at Loughborough University. Mark earned his Bachelors of Sport and Exercise Science at Liverpool John Moores University, where he also obtained his Master’s of science in sports nutrition.

I invited Mark to come on the podcast to talk about his current research into the effects of low energy availability on health and performance in humans. Specifically, we discuss low energy availability as it relates to bone health and the risk of bone stress injury in athletes. Mark has recently published a fantastic review article on the subject in the journal Sports Medicine, where he discusses the effects of low energy availability in weight-bearing endurance athletes as well as potential countermeasures to increase bone strength and bone health in these athletes.

Our discussion starts with some basic background into bone health and stress injuries, and then we dive in to defining low energy availability and how this condition affects bone health and other aspects of health in athletes. We then transition to talking about high-impact exercise as a novel countermeasure to increase bone health in athletes, and then end talking a bit about the role of nutrition and, specifically, protein and micronutrients, in bone health.

I really enjoyed this conversation with Mark and to be honest, my invite was a bit selfish in nature. I am all too familiar with bone stress injuries, actually having suffered multiple lower limb stress fractures, and even one hip fracture, over the course of the past few years. Whether this is due to low energy availability, a high amount of weight bearing exercise in the form of running, or a combination of both, I’m not quite sure, but a recent DEXA scan did reveal to me that my bone health was far from optimal and needed some intervention. This has been something on my mind for quite a while as I try to prevent further injury and set myself up for injury-free activity in the future. So I also wanted to pick Mark’s mind on some of my personal struggles with bone health and get some advice on tools that I might be able to implement to enhance my own bone health.

 

Links

- Follow Mark on Twitter @MarkJHutson

- Check out Mark’s research on Research Gate

- Read Mark’s review article: Effects of Low Energy Availability on Bone Health in Endurance Athletes and High-Impact Exercise as A Potential Countermeasure: A Narrative Review

- Listen on Apple Podcasts

- Listen on Spotify

- Support the podcast on Patreon

- Other support options

- Subscribe to the Physiology Friday newsletter

- Check out LMNT electrolytes

My guests today are Michael Brandt and Latt Mansor. Michael is the CEO at Health Via Modern Nutrition, a startup company selling nootropics and ketone supplements with the mission of redefining the limits of human performance, metabolism, and longevity. Latt is the research lead at HVMN and is responsible for coordinating clinical trials on their products as well as conducting internal research on up and coming products for the company.

 

Links

- HVMN Ketone 2.0

- Follow Michael on Twitter @bdm_runner

- Follow Latt on Twitter @lattmansor

- Support the podcast on Patreon

- Other support options

- Subscribe to the Physiology Friday newsletter

- Check out LMNT electrolytes

- Visit the episode webpage

In this Science & Chill podcast clip (from episode 38), Dr. Thomas Clanton explains the difference between free radicals and reactive oxygen species, and talks about the importance of these biological molecules.

Listen to the full episode HERE.

My guest today is Dr. Thomas Clanton. Dr. Clanton is a professor in applied physiology and kinesiology at the University of Florida, where he conducts research on immune cells in skeletal and cardiac muscle biology, the origins of heat stroke, and the effects of heat stroke on physiology and epigenetic regulation. Dr. Clanton is also a member of my PhD advisory committee and has been highly influential on the way I think about and do science throughout my graduate school career.

We begin our conversation with a deep and lengthy dive into Dr. Clanton’s scientific career — why he got into science, his early career work in respiratory and lung physiology, and what led him to become a cell biologist who now primarily focuses on animal models. We cover some basics of respiratory physiology and also talk about inspiratory muscle training devices — one for which Dr. Clanton actually has held a patent on for the last 40 or so years.

We then talk about free radical biology, reactive oxygen species in normal function and health and disease, and the key role of free radicals as signaling molecules throughout the body.

I was so glad to sit down with Dr. Clanton for our brief chat, and know that you will thoroughly enjoy this tour through what is a pretty jam-packed scientific career. 

 

Links:

UF Muscle Stress Physiology Lab:

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Donate to the podcast

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In this installment of Physiology Friday, I discuss a study investigating the effects of a 14-day ketone supplementation period on cerebral blood flow, cognitive performance, and BDNF in a group of individuals with obesity.

 

Links 

Study: Short-term ketone monoester supplementation improves cerebral blood flow and cognition in obesity: A randomized cross-over trial

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In this podcast clip, members of the Rogulja Lab from Harvard University explain what sleep is from a neurobiological perspective, whether sleep is essential, and if there are examples of living organisms that do not sleep. 

 

Listen to the full episode HERE.

In this episode of Science & Chill, I speak with Chris Cornell. I have been coaching Chris for the past 15 weeks as he embarks on his goal of breaking 25 minutes in the 5k at age 57, a feat he will attempt on Labor Day (September 6, 2021). Chris is very active on social media, where he posts about his diet, fitness, and has been documenting his 5k training for the past few months. 

In this conversation, we recap his training program, talk about some pre-race strategies, and answer some questions from Twitter about how Chris has approached his current running goals as well as his other goals in life. 

 

Links

- Follow Chris on Twitter @BiggestComeback

- Check out Chris's training on Strava

- Support Science & Chill on Patreon

- Listen/subscribe on Apple Podcasts

- Listen/subscribe on Spotify

In this Science & Chill podcast clip, Dr. Tamara Hew-Butler talks about whether drinking to thirst is an adequate way to stay hydrated and explains the origins of the recommendation to drink 8 glasses of water per day. 

 

Listen to the full episode here: Episode 35: Hydration Facts and Myths and Exercise-associated Hyponatremia with Dr. Tamara Hew-Butler