SciPod

The COVID-19 pandemic has dramatically changed how people work, travel, spend their free time, and interact with each other. This change was in large part influenced by the restrictions that governments put in place to limit the spread of the virus. Researchers at the Economic and Social Research Council Centre for Time Use Research, part of University College London, have been monitoring how people’s behaviours changed across different stages of the pandemic.

Chlamydia pneumoniae (or Cp for short) is a respiratory bacterium that causes treatable lung infections in humans and has been linked to the development of asthma. In a recent study, Dr David L. Hahn at St Mary’s Hospital in Madison, Wisconsin, USA, conducted a systematic review and meta-analysis of the available published data on the frequency and impact of Cp infection in child and adult asthma patients, and considered the potential implications for treatment.

Conventional agricultural practices have greatly increased the yield and efficiency of modern farming, allowing us to better feed a growing population. To protect crops from pests and disease, we rely heavily on chemical pesticides. However, the impacts of pesticide use are not localised to plants – there is growing awareness that pesticides can negatively affect many other organisms, including humans. Professor Kathleen Susman of Vassar College in New York, along with her colleagues, assessed whether a commonly used class of pesticides, neonicotinoids, have the potential to cause damaging effects in non-target organisms. Her findings also have implications for human health.

Many fields of experimental research are now facing a daunting challenge: despite the fact that separate research teams may work on the same system, the end results of their experiments can be widely varied. In his research, Dr Stanley Luck, at the Science, Technology and Research Institute of Delaware, explores the reasons behind this inherent inability to reproduce experimental results. Based on his analysis, he now suggests two key requirements that must be met to overcome this crisis, which could have a profound influence over the techniques employed by experimental researchers in the future.

Radio frequency inteferometric lightning maps are important tools for researchers exploring the electrical processes that unfold within storm clouds. Dr Xuan-Min Shao and colleagues at Los Alamos National Laboratory in New Mexico, who first introduced broadband interferometry to lightning research over two decades ago, have now developed an advanced ‘beam steering’ interferometry technique to significantly improve the accuracy of lightning mapping. This approach, together with their recently developed polarisation detection technique, has begun to reveal new physics involved in lightning discharges. Their recent work shows how lightning initiation, which has been poorly understood until now, may be linked to high-energy cosmic particles entering Earth’s atmosphere.

Engineering is one of the most impactful and transformative fields of teaching, research, and practice, as it shapes the world we live in and ensures the functioning of many systems that maintain human life. The Colorado School of Mines created the first Humanitarian Engineering (HE) program to train engineering students to devise solutions that are efficient, ethical, socially responsible and sustainable. Its students work closely with the communities they serve, thinking critically about their needs.

Hookah smoking is the least regulated tobacco form. It is rapidly gaining in popularity to the extent that we are now facing a contemporary epidemic of tobacco abuse. Of particular concern is the level of usage among youth and young adults. Professor Mary Rezk-Hanna from the University of California, Los Angeles works with a group of scientists who aim to drive policy regulation of tobacco and alternative tobacco products, including hookah smoking, by investigating their health effects on the cardiovascular system.

Domestic herbivores – such as cattle, sheep, and goats – are remarkably important to ecosystems. Their feeding behaviours aid the management of natural habitats by preventing any individual plant species dominating the landscape. Thus, understanding livestock dietary preferences is vital for informing land management decisions. Dr John Walker from the Texas A&M AgriLife Research and Extension Center has devoted his career to exploring livestock dietary preferences, and how they can be manipulated to benefit rangelands. His ‘Aggie Cedar Eater’ (ACE) goats are now helping to control invasive juniper shrubs across the Great Plains of the US.

Immune system cells express a number of receptors that bind to sugar ligands. This binding initiates the activation of T-cell lymphocytes and natural killer cells. Dr J. Kenneth Hoober, Dr Laura L. Eggink and the team at Susavion have designed peptides that bind to different receptors on immune cells. The peptides effectively extend the lives of mice with glioblastoma and ovarian cancer, and prevent the replication of viruses in the presence of non-neutralising antibodies. The mechanism of action of their peptides could inspire the development of effective treatments for Covid-19 and other viral infections.

Age-related macular degeneration (AMD) is an increasingly common disease that causes significant visual impairment. The implications include socioeconomic burdens for individuals and the population as a whole. Working to elucidate the issues surrounding AMD is Professor Gemmy Cheung, who holds senior roles at the Singapore National Eye Centre and the Singapore Eye Research Institute. She has brought together a group of expert scientists to form the Translational Asian Age-Related Macular Degeneration Program. The team is elucidating the mechanisms behind AMD to develop novel therapies, cultivate diagnostics and develop tools to better understand the impact of the disease from patients’ perspective.