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We all know exercise is good for us. In addition to the renowned physical benefits, Professor Kirk Erickson in the Department of Psychology at the University of Pittsburgh is providing powerful evidence that exercise may improve cognitive faculties throughout the lifespan. Read on to discover the wide range of ways in which exercise can help us to live our lives to the fullest across the years, and how the emerging field of health neuroscience may inform public health policy for our better good.

To understand how human activities impact wildlife, biologists need to know which species are present within a given area. Traditional methods of surveying species are often labour intensive, time consuming, and expensive. However, recent advancements in genetic analysis may provide powerful new survey tools to complement existing methods. Through her research, Dr Katy Klymus at the US Geological Survey tests the efficacy of one such tool, environmental DNA metabarcoding, for identifying wildlife affected by contaminated water sources.

Any injury such as trauma, surgery or infection to the cornea in the eye may result in persistent scarring (clinically referred to as fibrosis) due to the wound healing response. Professor Steven E. Wilson at the Cole Eye Institute of the Cleveland Clinic Foundation has identified that defective epithelial basement membrane (EBM) regeneration plays a central role in the development of scar producing myofibroblast cells. Critically, Professor Wilson suggests that the pathophysiological consequences of defective EBM regeneration are also likely to have wider relevance to the fibrosis that occurs in other organs, such as the lungs, heart, kidneys, and skin.

In the United States, there are thousands of industrial sites contaminated by the irresponsible disposal of chemical waste. The higher than expected frequency of cancer cases near these sites has caused alarm, since many of the chemical contaminants found at these sites have been linked to the development of long-term health problems, including cancer. As leaders of the Massachusetts Institute of Technology Superfund Research Program, Dr Jennifer Kay (Research Scientist and Research Translation Director) and Professor Bevin Page Engelward (Program Director) are using their expertise to investigate the genetic factors that influence susceptibility to adverse health outcomes following exposure to environmental chemicals.

Modern treatments for patients with more than one chronic condition can be highly precarious, and in many cases, simultaneous treatments for different illnesses can be detrimental to each other and ultimately, the patient. Dr Juliana Bowles at the University of St Andrews believes that this pressing issue can be solved with the help of advanced computational techniques. Her team has explored the ability of such techniques to calculate reliable outcomes within models of complex systems. Their work promises to significantly enhance the ways in which treatments for chronic conditions could be delivered – improving safety and quality of life for patients.

Neurodegenerative disorders present a major cause of death and disability worldwide. Treatments are typically expensive, non-efficient, and invasive. Although scientists are committed to finding better treatment strategies, the challenge of penetrating the blood-brain barrier remains. This highly selective envelope protects our brain from harmful substances but also prevents drugs from reaching the brain when needed. Dr Shikha Nangia at Syracuse University, USA, focuses on understanding the molecular structure of this complex interface to ultimately facilitate the transport of drugs across the blood-brain barrier.

Attempting suicide by ingesting pesticides is a major public health problem in rural Asia. In Sri Lanka, pesticide self-poisoning is the most common method used in suicide attempts in many rural areas. Globally, it accounts for as many as one in every five of the world’s suicides. Many people have recommended ‘safer storage and use’ as the answer to the problem. A group of Sri Lankan and international researchers took on the challenge to test, on a large scale, whether improving pesticide storage in households would actually reduce the frequency of self-poisoning with pesticides. Remarkably, they found no benefit from this approach at all. These findings have important implications for global policies aiming to reduce the incidence of suicide and self-harm.

When learning about fluid dynamics, physics and engineering students can benefit greatly from hands-on experiments that allow them to visualise the equations they learn in lectures. For supersonic flows, however, the equipment required is incredibly expensive, making some experiments inaccessible to many universities. Dr Oleg Goushcha at Manhattan College has revived an old methodology to demonstrate supersonic flows in the classroom using far more affordable equipment. He has shown that the features seen in supersonic can be accurately simulated through an inexpensive setup involving water surface waves.

Despite recent efforts to promote diversity in STEM education and professional environments, some ethnic groups remain highly underrepresented in STEM fields, including the Hispanic/LatinX community. To tackle this underrepresentation, researchers at the University of San Diego have created a multi-dimensional program funded by the National Science Foundation called STEMWoW, which is designed to promote and sustain interest in STEM disciplines among middle school students from underserved communities.

In certain areas of the US, local berry growers face difficulties in meeting the growing customer demand for high-quality berries, while also managing pests in sustainable ways. Aware of these challenges, researchers from different universities, including Michigan State, Penn State and Cornell Universities have been collaborating on a project called TunnelBerries. Their aim is to conduct research related to berry growing and provide berry crop producers with useful information, paving the way towards the use of forward-looking practices.