On review aggregator website Rotten Tomatoes, The Faculty received an approval rating of 55 percent based on 55 reviews, with an average rating of 5.60/10. The site's consensus reads, "Rip-off of other sci-fi thrillers." On Metacritic, the film has a score of 61 out of 100 based on 19 critics, indicating "generally favorable reviews." Audiences polled by CinemaScore gave the film an average grade of "B" on an A+ to F scale.
The Faculty was viewed on 2,365 screens its opening weekend, debuting at No. 5 in the US, making $11,633,495. Its eventual US gross was $40.3 million.
In retrospect, Jordana Brewster said:
It was sort of the inverse of Fast and Furious, right? So with The Fast and Furious, I was like, "This is a small movie about cars. It's a really fun summer project." ... With The Faculty it was like, "You guys, this is gonna be huge. Look at all these successes around us," like She's All That and Scream. ... And then it turned out it wasn't so huge. We thought it was gonna be massive ... But it was a cult classic so that’s really cool.
Clea Duvall is also very fond of the movie: "It was so much fun. It was mostly night shoots, so it was like we were in this alternate universe. Working all night long and making this fun sci-fi horror movie. I loved it."
The film has been praised for its portrayal of teenage alienation, especially within the high school environment and its system of cliques and social roles. In particular, the alien invasion through parasited bodies has been recognized as functioning as a metaphor for those concepts, reflecting the fear of losing one's nascent individuality to a crowd. The alien queen encapsulates this by offering the heroes a world without alienation or differences, in which "everything that is both wonderful and awful about being a teenager is done away in favor of blind allegiance".
Experts also noted in The Faculty a reinvention of the fear of female sexuality often found in the horror genre. The character of Marybeth, the alien queen, is "a complex imbrication of woman, alien and power" that acts beyond the role of femme fatale. She masquerades as a virginal, unassuming girl clad in floral dresses, but at the final battle she reveals her true sexual threat, becoming nude by her alien transformation and turning confident and flirtatious. Her role as a threatening, castrating agent is underlined by the sharp teeth of her species, which evoke a vagina dentata, and their association to water, the archaic, womb-like female element. As the monstrous mother of her race, she tries to seduce the heroes by offering them a symbolic return to the womb. As Sharon Packer and Jody Pennington put it:
The image on the screen is dual: we see the beautiful, young, naked Marybeth strolling around looking for Casey, and the shadow of the monstrous form in the walls. Marybeth delivers a speech which ties the elements of the movie together. It is about the "world" she came from and its promises of "paradise" for lost and lonely humans, trapped in high-school "hell".
The character of Miss Burke precedes Marybeth in the same line, revealing her hidden sexuality only after being infected and turned into a monster. The scene of her detached, tentacled head in particular echoes the Freudian Medusa head. The monstrous feminine is therefore used in the film to reflect the teenage characters entering adult world, where they are forced to "come to terms with female sexuality and overcome their fear of its 'monstrous' aspects in order to become fully functioning adults". Casey, the male character closest to his softer, feminine side, is the final hero of the film.