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We welcome back our very own Dr Toby Talbot Consultant Clinical Oncologist at Royal Cornwall Hospital for his patient-focussed insights into managing early stage melanoma.

In this two part series, we explore what melanoma is, why it comes about and how it is investigated.

We discuss surgery, why this might be a two stage procedure and the importance of sentinel lymph node biopsy. 

We then delve into some of the drug treatments available, used to reduce the risk of the cancer coming back. We focus mainly on immunotherapy and the possible benefits of treatment in Part 1.

Tune in next week for Part 2 where we explore some of the side effects of treatments, BRAF directed therapy and how these drugs are possibly going to be used before surgery.

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Join us for something a bit different this week!!

We though it would be fun ( and hopefully helpful) to make an A to Z of Oncology.

Are you a patient or care who is newly diagnosed with cancer.

Are you new to working around cancer care.

Are you in training and want to learn more.

Indeed- are you in cancer care and want to know why we have chosen our A to Z.

We get the super experienced Clinical Nurse Specialist Debbie Victor to help us out. As Education trustee for the British Association of Urology Nurses she knows a thing or 2 about supporting patients in cancer.

If you have a better A to Z please feel free to contact us and let us know!!

If you want a recap the list is in the transcript👍

Enjoy

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Join us as we tackle the topic of Artificial intelligence in Radiotherapy.

This week we speak to the excellent Professor Ajay Aggarwal about the use of AI in radiotherapy planning.

We discuss the international ARCHERY trial using an AI radiotherapy planning tool to  streamline radiotherapy planning in prostate, head & neck and cervical cancers. 

This PRA artificial planning tool developed at the MD Anderson hospital could unlock huge radiotherapy delivery potential in Low & middle income countries and beyond!

This trial of 990 patients is being conducted in Jordan, South Africa, India and Malaysia.

All radiotherapy trials are hard to get funded. This remains an area of need for oncology trial funding.

Massive respect and congratulations to Ajay and the international team for getting unified treatment protocols and to actually prospectively test and AI solution in radiotherapy.

We hope you enjoy

Link below to the ARCHERY trial manuscript.

https://bmjopen.bmj.com/content/13/12/e077253

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🎙️New Simply Oncology Podcast to complete our PSMA Lutetium in #ProstateCancer

🎙️Join us for the Part 2 of our masterclass with the superb Dr Amy Eccles⭐️

As we focus on #ProstateCancerAwarenessMonth we look at future directions for PSMA Lutetium in Prostate Cancer.

The British Nuclear Medicine Society are having there annual conference this week. Molecular radiation may offer amazing treatment options in the near future🙌🏽

See link below👇or wherever you get your podcasts ⭐️

https://lnkd.in/eJ7Zy5e8

Enjoy☢️

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PSMA Lutetium has been in the background for metastatic prostate cancer for several years.

Joins us as we discuss this exciting treatment in metastatic prostate cancer with the excellent Dr Amy Eccles who works at Imperial Hospital London and also the London Clinic. Amy is a radiologist who delivers PSMA Lutetium at the London Clinic and shares her experience with us.

Attaching Lutetium-177 to PSMA to deliver a beta-emitting radiation payload to prostate cancer cells. Essentially targeted liquid radiotherapy.

This is novel therapy that is not yet funded in the NHS.

We discuss who a good patient may be and what potential side effects they could expect.

This field of Theranostics is expending rapidly and where does this sit with our current prostate cancer treatment landscape??

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Late effects after pelvic radiotherapy part 2.

Join us as we complete our conversation with the wonderful Macmillan Late effects consultant radiographer Lisa Durrant.

Last week we discussed late bladder and bowel effects from radiotherapy.

In this weeks episode we discuss;

- hyperbaric oxygen therapy 

- pelvic floor exercises

- pain as a late effect of radiotherapy

- sexual function issues post radiotherapy

Lisa gives us some great practical tips on how to support patients after their radiotherapy along the way.

Enjoy!

For more info on pelvic radiation disease and late effects from pelvic radiation check out www.prda.org.uk 

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Join us as we discuss the impact of Pelvic Radiation Disease & the late effects of radiotherapy in the pelvis.

We re always trying to get he best result for our patients and to cure cancer but we need to take time to deal with the impact of radiotherapy side effects in our patients.

We are talking radiotherapy for pelvic cancers; bladder, prostate, gynaecological and rectal cancers.
Lisa is a consultant radiographer pioneering support for patients with late effects of radiotherapy. She leads her radiotherapy late effects service at Musgrove Park hospital in Taunton.

In this first of 2 parts we discuss;
🔎 What is Pelvic radiation Disease
🔎 When are effects 'Late Effects' from radiotherapy
🔎 Strategies for dealing with bladder and bowel side effects

A must listen for anyone who is delivering pelvic radiotherapy and a useful tool for patients receiving radiotherapy to the pelvis.

Enjoy!!

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Join us as return to our excellent conversation on biomarkers in kidney cancer with the wonderful Professor Laurence Albiges from Paris.

🎙️We finish our overview of Biomarkers in metastatic Kidney Cancer with the superb Professor Laurence Albiges from the Gustave Roussy  Hospital in Paris 🇫🇷

Which biomarker will help us to decide which treatment to select in metastatic #KidneyCancer
- IOIO vs IOTKi
- when to start therapy
- monitoring on treatment 

An exciting space and none better than Laurence to walk us through it.

💊KIM 1
💊 CtDNA
💊Microbiome
💊PDL1
💊NLR

Which will be our winner in 2026⭐️

🇫🇷Also with 2 minute summary in French for anyone wanting an oncology version of Duolingo 🇫🇷

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Join us for a special Kidney Cancer treat!!!

A Must Listen episode!!

We discuss the role of biomarkers in advanced kidney cancer with the wonderful Professor Laurence Albiges from the Gustave Roussy Institute of Oncology in Paris.

No Kidney Cancer talk is complete without the question -" Where are we with biomarkers?"

This is part 1 of a 2 part walkthrough of the biomarker story so far in kidney cancer.

Laurence is unequalled in her clear delivery on this subject.

As lead for the CARE-1 study Laurence is examining the role of PDL1 as a biomarker in 1st line treatment of mRCC.

We also discuss the;

- IMDC criteria

- Clusters

- KIM-1

- PDL1

- Sarcomatoid features

Recorded before Christmas this is a gift that keeps on giving.

We hope you enjoy!!

Check the Transcript for more details.

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Join us as we return to complete our run through the landscape of metastatic renal cancer with the effervescent Professor Ricky Frazer.

We look at the Dolly Mixture of subtypes that makes up non clear cell renal carcinoma.

We discuss the new HIF2a inhibitors such as belzutifan.

We look at future directions in kidney cancer.

A treat for anyone who treats kidney cancer.

Enjoy!