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Lifestyle and patient choices in Prostate Cancer

Prostate cancer has been part of a revolution in terms of treatment options and improved outcomes for our patients. How can we make that improvement in numbers on survival curves match the goals and needs of our patients?

Join us in this second of 2 special live episodes of the Simply Oncology Podcast on Patient Choices and Lifestyle in Prostate Cancer.

We talk to patient expert Tony Collier, Dr Lucy Gossage - an oncologist involved with Move Against Cancer and  Professor Alison Birtle an oncologist with extensive experience treating prostate cancer.

In this Episode we focus on Dr Lucy Gossage and her experience of supporting cancer. patients through exercise 

Lucy Gossage has a background in international level sport alongside being an oncologist, so it seemed natural for her to be involved in Move Against Cancer. 

We discuss the massive positive steps that giving patients permission to move and exercise can have for their health -both physical and mental.

Recapturing some normality amongst the backdrop of cancer and its treatment can only be a good thing for patients.

We hear about the huge positive impact that maintaining exercise has had on Tony’s life with cancer. 

We hope you enjoy!

*This is a non-promotional podcast episode organised by Bayer PLC in partnership with Simply Oncology (Dr John McGrane and Dr Michael Rowe) to highlight the importance of holistic care in managing patients with prostate cancer. Bayer provided honoraria to the speakers of this podcast. The views and opinions expressed are those of the speakers and do not necessarily reflect those of Bayer PLC or Simply Oncology. This content is for educational purposes only and should not replace clinical judgement.*

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Lifestyle and patient choices in Prostate Cancer

Prostate cancer has been part of a revolution in terms of treatment options and improved outcomes for our patients. How can we make that improvement in numbers on survival curves match the goals and needs of our patients?

Join us in this first of 2 special live episodes of the Simply Oncology Podcast on Patient Choices and Lifestyle in Prostate Cancer.

We talk to patient expert Tony Collier, Dr Lucy Gossage - an oncologist involved with Move Against Cancer and  Professor Alison Birtle an oncologist with extensive experience treating prostate cancer.

In this Episode  we talk to Tony Collier about his experience of being a prostate cancer patient. We hear how the focus on treatment led him to have to advocate his quality of life and life goals himself. We hear how clinicians could align with patients’ goals with just a few simple questions. 

We hear about the huge positive impact that maintaining exercise has had on Tony’s life with cancer. 

Hearing Tony’s live experience of some very personal aspects of a cancer diagnosis and treatment is hugely moving and powerful.

We hope you enjoy!

*This is a non-promotional podcast episode organised by Bayer PLC in partnership with Simply Oncology (Dr John McGrane and Dr Michael Rowe) to highlight the importance of holistic care in managing patients with prostate cancer. Bayer provided honoraria to the speakers of this podcast. The views and opinions expressed are those of the speakers and do not necessarily reflect those of Bayer PLC or Simply Oncology. This content is for educational purposes only and should not replace clinical judgement.*

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Join us as we finish our discussion on managing menopause in gynaecological cancers with the wonderful Shibani Nicum.

Shibani works as as Associate Professor in Medical oncology treating gynaecological cancers at UCL Hospitals London.

Shibani helped se up the meno.pause app in conjunction with the British Menopause Society to help guide clinical teams to support patients with menopause issues as part of their gynae cancer treatment.

We look at setting up a complex menopause MDT and what lifestyle factors can help in this setting.

As we see ongoing improvements in survival outcomes maintaining quality of life is so important and managing menopausal issue is a big part of that quality of life.

Enjoy

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Menopause in Gynae Cancer patients is a major issue.

If you struggle when to advise patients in this space.

Join us  as we discuss management of menopause in gynae cancer patients with excellent Dr Shibani Nicum from UCL hospitals London.

Menopause across all cancer affects up to 60000 patients per year!

In Gynae cancers such as ovarian cancer we can make someone menopausal immediately after surgery so that person is coping with menopause alongside surgery and chemotherapy side effects.

Shibani has helped to develop the Meno.pause app to support healthcare teams with menopause treatment in cancer.

It’s not just HRT - how best can we help support patients.

- Oxybutynin

- Neurokinin inhibitors

- Lifestyle

We discuss this and more

Enjoy!

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Join us for this special episode where we look at the recent major changes in the Platinum resistant ovarian cancer space .

For so long this has been a treatment area with limited options  and poor outcomes.

Now we have ;

- New Drugs

- New targets

- Better outcomes

So much to discuss. 

We talk to the brilliant Dr Rowan Miller who specialises in gynaecological cancers and is based at UCL & St Barts Hospitals in  London.

Straight after her presentation on B7-H4 ADCs at the British Gynaecological Cancer Society meeting in Bristol we look at the new options and where they might sit in our treatment pathway?

Will they all get funded?

Can we manage the new side effects?

Could they work in sequence or together??

A 'Must Listen' if you are involved in Ovarian Cancer.

Enjoy

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Join us as we return with the wonderful Professor Mark Beresford from United Hospitals in Bath.

We discuss how we as clinicians describe risk to our patients ans we look at some of the pitfalls of using relative risk, overcomplicated statistics with our patients.

If we cannot explain risk to patients how can they ,make informed decisions.

Mark moves into 'T-shirt Territory' by being our most frequent flyer on the podcast which earns him a coveted Simply Oncology Podcast T-Shirt.

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Join us as we return to our discussion on the fascinating ADePT trial in Glioblastoma brain tumours with the wonderful Dr Faye Robertson from the Western General Hospital, Edinburgh.

We discuss how TGX-007 developed with TROGENIX with its super enhancers, dual payload and delivery system hopes to bring a break through in High grade Gliomas.

We talk about how could this technology be 'rolled out' if successful. What level of success would be needed to develop the specialism for this kind of treatment.

Could this therapy be adapted to be used in other cancer types such as pancreatic cancer etc ?

With only 1 human trial patient clearly this is early days but we hope to follow this trial's progress on The Simply Oncology Podcast.

Even if the survival outcomes of the trial were negative this trials move the dial in terms of what is possible from drug development and delivery.

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Sometimes we hear about a vision for a trial that is so novel and exciting that it takes you back a bit.

This is one such moment.

Join us as we talk to the amazing Dr Faye Robertson from the Edinburgh cancer Centre about the ingenious ADePT trial.

DUAL PAYLOAD GENE THERAPY.

Led by Trogenix and the University of Edinburgh, it tests a breakthrough "Trojan horse" gene therapy designed to destroy cancer cells and stimulate the immune system.

TGX-007 is a drug developed with Tregonix that:

How it Works: It uses dual-payload technology to deliver two distinct therapeutic agents:

1. HSV-tk: Converts an orally administered antiviral drug (valaciclovir) into a toxic agent that directly kills proliferating tumour cells.
2. IL-12: Acts as an immune-stimulating cytokine that turns the tumour into an in-situ vaccine, training the body's immune system to attack the cancer and prevent recurrence.

We have had many false dawns in GBM trials but we are very excited by the results so far with TGX-007.

Part 1 of 2 and this is a trial story we want to follow through.

Enjoy!!!

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We return to discuss the role of radiotherapy in the management of Pancreatic Cancer.

What are the side effects of pancreatic radiotherapy and SABR?

Do we need an MR Linac to deliver pancreatic SABR

Where might pancreatic RT sit alongside new RAS inhibitor therapies?

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Today we are talking about the role of radiotherapy in Pancreatic Cancer with the superb Dr Ganesh Radhakrishna from the Christie Hospital in Manchester.

Radiotherapy may play an increasing role in pancreatic cancer. Stereotactic ablative body radiotherapy (SABR) is helping to get excellent control rates in localised pancreatic cancer and may play a role alongside surgery in pancreatic cancer.

Will radiotherapy ever replace surgery in select cases?