Skin and Joints Podcast

 Part 3 of 3: Our Practical Playbook When Skin & Gut Don’t Read the Same Treatment Plan

What happens when the skin is crystal clear…but the Crohn’s disease didn’t get the memo? 👀

In the final chapter of our special Derm × GI crossover conversation, our Faculty Dr. Perry Grewal and Dr. Jesse Siffledeen get practical about what happens after the prescription is written.

From treat-to-target monitoring and follow-up cadence to the very real influence of insurance requirements, our experts unpack how they decide whether a therapy is truly working—and what to do when different organ systems are telling very different stories.

🧩 Great skin, active gut?
🧩 Controlled IBD, stubborn psoriasis?
🧩 One therapy, two diseases…or occasionally two therapies?

The conversation explores how clinicians prioritize competing treatment targets without sacrificing what matters most to the patient, why success may need to be measured beyond a single organ system, and where communication between specialties becomes essential.

And perhaps the simplest clinical pearl of the entire series? Ask the questions—and don’t be afraid to pick up the phone.

Because when inflammatory disease crosses specialties, the best care probably should too.

🎯 Learning Objectives

After listening to this episode, participants should be able to:

1. Describe practical approaches to monitoring treatment response across dermatologic and gastrointestinal inflammatory diseases, including the role of early clinical follow-up and objective assessment.
2. Evaluate therapeutic options when disease control differs across organ systems, such as controlled psoriasis with active IBD or controlled IBD with persistent skin disease.
3. Discuss the limitations of organ-specific treatment targets and incorporate patient priorities, disease severity, and multisystem outcomes when defining therapeutic success.
4. Recognize how payer and insurance requirements can influence treatment selection, reassessment schedules, access, and consideration of dual therapy.
5. Identify key questions that dermatology and gastroenterology clinicians can ask to recognize disease manifestations outside their own specialty and facilitate timely referral.
6. Apply practical strategies for multidisciplinary co-management, including direct clinician-to-clinician communication and collaborative treatment decision-making,

🔥 In This Episode

🔬 Treat-to-target: when should you actually reassess?
🎯 One patient, two organs: does success require both to be at target?
🔄 Great skin, active gut—or vice versa: when do you switch?
💊 Dual therapy: useful tool or access nightmare?
💰 When insurance starts influencing the clinical calendar
🗣️ Why asking about the gut–skin–joint connection matters
📞 The underrated power of simply calling your colleague
🤝 Why multidisciplinary care needs to move from concept to everyday workflow

#SkinAndJoints #Dermatology #Gastroenterology #IBD #CrohnsDisease #Psoriasis #SkinGutAxis #TreatToTarget #Biologics #IL23 #InflammatoryDisease #MultidisciplinaryCare #PrecisionMedicine #PatientCentredCare #MedicalEducation #HCPeducation

SUPPORTED BY AN IME GRANT FROM JnJ Johnson and Johnson.

ABOUT Dr. Parbeer Grewal

Dermatologist, Edmonton, AB

Dr. Parbeer Grewal completed his Bachelor of Science undergraduate degree at the University of Alberta with a specialization in Psychology and graduated with distinction. He completed his Doctorate of Medicine degree at the University of Alberta and graduated with Special Training in Research. He completed dermatology training at the University of Alberta and became a Fellow of the Royal College of Physicians and Surgeons of Canada and a board-certified Fellow of the American Academy of Dermatology. 

Dr. Grewal is an Associate Clinical Professor within the University of Alberta’s Faculty of Medicine - Dermatology. In addition to working at Rejuvenation, he is a consulting physician for the University of Alberta Hospital, the Royal Alexandra Hospital, the Grey Nuns Hospital and the Misericordia Hospital. Dr. Grewal has participated in over 60 clinical research trials for a multitude of dermatology conditions and medications. In addition, Dr. Grewal serves on multiple national and international scientific advisory boards, is a distinguished peer reviewer for medical journals and has published both journal articles and book chapters in dermatology. 

He has specific interests in psoriasis, acne, eczema, warts, skin cancers, rashes and moles. He offers a wide range of topical and systemic therapy along with surgical and aesthetic services.

ABOUT Dr. Jesse Siffledeen, MD, FRCPC 
Gastroenterology, Edmonton, AB

Dr. Siffledeen is a clinical professor in the Division of Gastroenterology at the University of Alberta. He is also currently the past-president of the Alberta Society of Gastroenterology. He has established a large clinical IBD practice in Edmonton and is the director of the South Edmonton Gastroenterology Research Unit, serving as principal investigator and collaborator on several IBD-related clinical trials for over 20 years.  He is an active collaborator in the Edmonton IBD research community and as a member of the Canadian IBD research consortium.

Dr. Siffledeen completed his Gastroenterology studies at the University of Alberta in 2010 and inflammatory bowel disease research/Master’s degree at the University of Oxford in 2011. 

📻www.skinandjoints.ca

✉️[email protected]

🎙️ Beyond Skin Deep & Gut Feelings — Part 2: When the Gut and Skin Share the Treatment Plan

One patient. Two organ systems. And suddenly, choosing a biologic gets a whole lot more interesting. 👀

In Part 2 of our Derm × GI crossover, podcast Faculty members dermatologist Dr. Perry Grewal and gastroenterologist Dr. Jesse Siffledeen move from diagnosis into the real-world treatment decisions that happen when psoriasis and inflammatory bowel disease collide.

PRO-TIPS COVERED: How do you practically choose one therapy when you’re treating two inflammatory diseases? When might suspected IBD steer a dermatologist away from an IL-17 inhibitor? What happens when the dose needed for Crohn’s disease doesn’t match the dose used for psoriasis? And when one drug isn’t enough, is dual advanced therapy the next frontier—or an insurance headache waiting to happen? 😅

The conversation also digs into the very different therapeutic ceilings in dermatology and gastroenterology, including emerging data in perianal Crohn’s disease, the challenge of achieving true mucosal healing, and why GI may still be chasing remission rates that dermatology has already learned to expect from modern psoriasis therapy.

It gets practical: Who owns the prescription? Who takes the lead when one organ system flares? How much communication is really needed between specialists? And where do vaccinations fit when advanced therapy needs to start quickly?

From IL-23s vs IL-17s to biologic dosing, multidisciplinary care, vaccine timing and the occasional therapeutic turf war, this is where “shared care” leaves the PowerPoint slide and enters actual clinical practice. 🧩

🎯 Learning Objectives

After listening to this episode, participants should be able to:

1. Compare key clinical factors that influence advanced therapy selection in patients with psoriasis and coexisting or suspected inflammatory bowel disease.
2. Explain how IL-17, IL-23 and TNF-targeted therapies may be approached differently when Crohn’s disease, fistulizing disease or possible IBD is part of the clinical picture.
3. Discuss real-world challenges in multidisciplinary treatment, including differing doses across indications, prescription ownership, reimbursement barriers and situations where dual advanced therapy may be considered.
4. Contrast treatment targets in psoriasis and IBD, including PASI-based skin clearance versus clinical remission, endoscopic improvement and mucosal healing.
5. Identify practical approaches to vaccination and treatment onboarding for patients starting biologic or other advanced systemic therapies.

🎧 Part 2 of 3 — stay tuned for Part 3 as the conversation moves into monitoring and treat-to-target across the skin–gut axis.

#SkinAndJoints #Dermatology #Gastroenterology #IBD #CrohnsDisease #Psoriasis #SkinGutAxis #Biologics #IL23 #IL17 #TNFInhibitors #InflammatoryDisease #PrecisionMedicine #MultidisciplinaryCare #MedicalEducation #HCPeducation 🧬🩺💊

SUPPORTED BY AN IME GRANT FROM JnJ Johnson and Johnson.

ABOUT Dr. Parbeer Grewal

Dermatologist, Edmonton, AB

Dr. Parbeer Grewal completed his Bachelor of Science undergraduate degree at the University of Alberta with a specialization in Psychology and graduated with distinction. He completed his Doctorate of Medicine degree at the University of Alberta and graduated with Special Training in Research. He completed dermatology training at the University of Alberta and became a Fellow of the Royal College of Physicians and Surgeons of Canada and a board-certified Fellow of the American Academy of Dermatology. 

Dr. Grewal is an Associate Clinical Professor within the University of Alberta’s Faculty of Medicine - Dermatology. In addition to working at Rejuvenation, he is a consulting physician for the University of Alberta Hospital, the Royal Alexandra Hospital, the Grey Nuns Hospital and the Misericordia Hospital. Dr. Grewal has participated in over 60 clinical research trials for a multitude of dermatology conditions and medications. In addition, Dr. Grewal serves on multiple national and international scientific advisory boards, is a distinguished peer reviewer for medical journals and has published both journal articles and book chapters in dermatology. 

He has specific interests in psoriasis, acne, eczema, warts, skin cancers, rashes and moles. He offers a wide range of topical and systemic therapy along with surgical and aesthetic services.

ABOUT Dr. Jesse Siffledeen, MD, FRCPC 
Gastroenterology, Edmonton, AB

Dr. Siffledeen is a clinical professor in the Division of Gastroenterology at the University of Alberta. He is also currently the past-president of the Alberta Society of Gastroenterology. He has established a large clinical IBD practice in Edmonton and is the director of the South Edmonton Gastroenterology Research Unit, serving as principal investigator and collaborator on several IBD-related clinical trials for over 20 years.  He is an active collaborator in the Edmonton IBD research community and as a member of the Canadian IBD research consortium.

Dr. Siffledeen completed his Gastroenterology studies at the University of Alberta in 2010 and inflammatory bowel disease research/Master’s degree at the University of Oxford in 2011. 

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

Not every loose stool is Crohn’s. Not every rash is “just a rash.” And sometimes the most useful clinical tool is knowing exactly which colleague to text.

In Part 1 of our special Skin and Joints Podcast crossover, we go beyond skin deep and gut feelings with dermatologist Dr. Perry Grewal and gastroenterologist Dr. Jesse Siffledeen to tackle what Derm–GI collaboration actually looks like, or could look like in the real world.

Psoriasis and inflammatory bowel disease may live in different specialty clinics, but for many patients, the boundaries aren’t nearly so tidy.

What should make a dermatologist start thinking about the gut? Which GI symptoms deserve a routine referral—and which ones should make your clinical “spidey sense” start tingling?

Our guest experts get practical about:

🔎 The GI red flags worth screening for in patients with psoriatic disease
🚨 When a referral can wait—and when it probably shouldn’t
🧪 Where fecal calprotectin, inflammatory markers and anemia fit into the picture
📲 Why sometimes a colleague’s name, and a quick message can be more useful than an elaborate referral pathway
📝 What actually needs to go into a useful Derm-to-GI or GI-to-Derm referral
🧩 How to begin separating IBD from common mimics such as IBS and post-infectious symptoms
💊 Why recognizing coexisting immune-mediated disease can influence treatment decisions

And perhaps most importantly: multidisciplinary care doesn’t always require a multidisciplinary clinic.

🎯 Learning Objectives

By the end of Part 1, listeners should be able to:

1. Recognize key gastrointestinal signs, symptoms and clinical red flags that may warrant further investigation for IBD in a patient presenting with psoriatic disease.
2. Differentiate between routine, urgent and potentially emergent GI referral scenarios based on symptoms, systemic illness and available objective findings.
3. Describe practical strategies for Derm–GI co-management, including effective communication and the essential information to include when referring between specialties.
4. Explain how suspected or confirmed gastrointestinal comorbidity may influence therapeutic decision-making in patients with immune-mediated disease.
5. Identify clinical features that can help distinguish IBD from common gastrointestinal mimics, while recognizing when specialist assessment is warranted.

🎧 Two specialties. One patient. And a lot more overlap than the clinic schedule might suggest.

#SkinAndJointsPodcast #Dermatology #Gastroenterology #Psoriasis #IBD #CrohnsDisease #UlcerativeColitis #ImmuneMediatedDisease #MultidisciplinaryCare #MedicalEducation #DermGI #ClinicalPractice

SUPPORTED BY AN IME GRANT FROM JnJ Johnson and Johnson.

ABOUT Dr. Parbeer Grewal

Dermatologist, Edmonton, AB

Dr. Parbeer Grewal completed his Bachelor of Science undergraduate degree at the University of Alberta with a specialization in Psychology and graduated with distinction. He completed his Doctorate of Medicine degree at the University of Alberta and graduated with Special Training in Research. He completed dermatology training at the University of Alberta and became a Fellow of the Royal College of Physicians and Surgeons of Canada and a board-certified Fellow of the American Academy of Dermatology. 

Dr. Grewal is an Associate Clinical Professor within the University of Alberta’s Faculty of Medicine - Dermatology. In addition to working at Rejuvenation, he is a consulting physician for the University of Alberta Hospital, the Royal Alexandra Hospital, the Grey Nuns Hospital and the Misericordia Hospital. Dr. Grewal has participated in over 60 clinical research trials for a multitude of dermatology conditions and medications. In addition, Dr. Grewal serves on multiple national and international scientific advisory boards, is a distinguished peer reviewer for medical journals and has published both journal articles and book chapters in dermatology. 

He has specific interests in psoriasis, acne, eczema, warts, skin cancers, rashes and moles. He offers a wide range of topical and systemic therapy along with surgical and aesthetic services.

ABOUT Dr. Jesse Siffledeen, MD, FRCPC 
Gastroenterology, Edmonton, AB

Dr. Siffledeen is a clinical professor in the Division of Gastroenterology at the University of Alberta. He is also currently the past-president of the Alberta Society of Gastroenterology. He has established a large clinical IBD practice in Edmonton and is the director of the South Edmonton Gastroenterology Research Unit, serving as principal investigator and collaborator on several IBD-related clinical trials for over 20 years.  He is an active collaborator in the Edmonton IBD research community and as a member of the Canadian IBD research consortium.

Dr. Siffledeen completed his Gastroenterology studies at the University of Alberta in 2010 and inflammatory bowel disease research/Master’s degree at the University of Oxford in 2011. 

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

🎙️ HS & Biosimilars: The Switch Pitch — Part 3

Final drop, biggest pearls. 💎

Is HS is the new acne? How can we treat early, treat seriously, and help prevent long-term scarring—physical and emotional?

In Part 3 of our real-world HS conversation, Skin and Joints Podcast F aculty Dr. Lauren Lam and Dr. Marni Wiseman bring the discussion home with practical, clinic-ready insights for dermatologists navigating biosimilars, biologics, comorbidities, obesity, smoking, PSP realities, and the art of building trust over time.

From why GLP-1s are not a substitute for HS-directed biologic therapy, to how to incorporate non-stigmatizing conversations around obesity and smoking cessation in the clinic, this episode gets into the real-world nuance that does not always fit neatly into an algorithm. 

And when it comes to choosing between a TNF biosimilar and IL-17 options?  How dos comorbidities, contraindications, access, PSP fit, disease severity, and the patient sitting in front of you all factor in for each? Find out here. 👩‍⚕️🧠

Learning Objectives

#SkinAndJointsPodcast #HidradenitisSuppurativa #HSawareness #Dermatology #Biosimilars #Biologics #InflammatorySkinDisease #MedicalEducation #DermTwitter #DermatologyEducation #PatientCentredCare #RealWorldDermatology #PSP #IL17 #TNF #ClinicalPearls 💉🧬🎙️

ABOUT Dr. Lauren Lam BScH, MD, FRCPC

​​Medical, Surgical & Cosmetic Dermatologist CALGARY, AB

Dr. Lam is the Vice President of the Canadian Hidradenitis Suppurativa Foundation and a Canadian Board Certified Dermatologist subspecializing in Hidradenitis Suppurativa Deroofing Procedures.  She runs a weekly deroofing clinic in Calgary, Alberta, and has done 1500+ cases to date.  

Besides collaborating on global HS projects, her other favourite endeavours include being an international explorer, culinary enthusiast and aunt to 5 dogs.

ABOUT Dr. Marni C. Wiseman MD FRCPC DABD

Associate Professor, Section Head Dermatology University of Manitoba

Director, SKiNWISE DERMATOLOGY and Wiseman Dermatology Research

Dr. Marni C. Wiseman began her Dermatology practice in Winnipeg, Manitoba in 2001.She is an Associate Professor and Section Head of Dermatology at the Faculty of Medicine at the University of Manitoba. Dr. Wiseman is the Medical Director of SKiNWISE DERMATOLOGY, where she conducts her private medical practice.  

Dr. Wiseman’s areas of clinical and research interest include inflammatory disease: psoriasis, atopic dermatitis, hidradenitis suppuritiva, vitiligo, alopecia areata, urticaria, and acne vulgaris.

Dr Wiseman is Principal Investigator at Wiseman Dermatology Research and has participated in hundreds of clinical trials and registry studies. Dr. Wiseman is a frequent lecturer at meetings and congresses nationally and internationally and is extensively published in areas of inflammatory skin disease, photodermatosis, and cutaneous malignancy. Dr. Wiseman is a supervisor and mentor for medical students and residents, conducts regular rural/remote outreach clinics, has significant volunteer involvement with the Canadian Dermatology Association, the Canadian Hidradenitis Suppuritiva Foundation, and is an editor of the Journal of Cutaneous Medicine and Surgery.

EPISODE SUPPORTED BY CELLTRION CANADA

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

🎙️ PART 2:  HS & Biosimilars: The Switch Pitch — Real-World Pearls from the Clinic 💉🔥🧴

Faculty Dr. Lauren Lam and Dr. Marni Wiseman join the Skin and Joints Podcast to unpack what really matters when biosimilars move from policy, paperwork, and prescribing forms… into the real lives of patients with hidradenitis suppurativa. 📋➡️💪

From the science of biosimilarity and extrapolating evidence across inflammatory diseases, to the clinic-level details dermatologists cannot afford to overlook — injection pain, citrate-free formulations, device ergonomics, dosing convenience, patient support programs, rural drug delivery, reload strategies, and yes… whether the PSP actually calls the patient back. ☎️🚚💉

Because in HS, the best biologic or biosimilar is not just about the molecule. It is about momentum, access, trust, support, and getting treatment into the patient’s hands before they disappear from the care journey. 🧭🤝

The conversation also takes a timely turn into obesity, systemic inflammation, GLP-1/GIP therapies, and whether metabolic care may become part of the next frontier in HS management. ⚖️🔥🔬

Consider this your field guide to biosimilar switching in HS — with clinic hot tips, PSP reality checks, and a reminder that sometimes the smallest formulation detail can make the biggest difference to the person injecting every week. 💡💉🙌

Learning Objectives:

ABOUT Dr. Lauren Lam BScH, MD, FRCPC

​​Medical, Surgical & Cosmetic Dermatologist CALGARY, AB

Dr. Lam is the Vice President of the Canadian Hidradenitis Suppurativa Foundation and a Canadian Board Certified Dermatologist subspecializing in Hidradenitis Suppurativa Deroofing Procedures.  She runs a weekly deroofing clinic in Calgary, Alberta, and has done 1500+ cases to date.  

Besides collaborating on global HS projects, her other favourite endeavours include being an international explorer, culinary enthusiast and aunt to 5 dogs.

ABOUT Dr. Marni C. Wiseman MD FRCPC DABD

Associate Professor, Section Head Dermatology University of Manitoba

Director, SKiNWISE DERMATOLOGY and Wiseman Dermatology Research

Dr. Marni C. Wiseman began her Dermatology practice in Winnipeg, Manitoba in 2001.She is an Associate Professor and Section Head of Dermatology at the Faculty of Medicine at the University of Manitoba. Dr. Wiseman is the Medical Director of SKiNWISE DERMATOLOGY, where she conducts her private medical practice.  

Dr. Wiseman’s areas of clinical and research interest include inflammatory disease: psoriasis, atopic dermatitis, hidradenitis suppuritiva, vitiligo, alopecia areata, urticaria, and acne vulgaris.

Dr Wiseman is Principal Investigator at Wiseman Dermatology Research and has participated in hundreds of clinical trials and registry studies. Dr. Wiseman is a frequent lecturer at meetings and congresses nationally and internationally and is extensively published in areas of inflammatory skin disease, photodermatosis, and cutaneous malignancy. Dr. Wiseman is a supervisor and mentor for medical students and residents, conducts regular rural/remote outreach clinics, has significant volunteer involvement with the Canadian Dermatology Association, the Canadian Hidradenitis Suppuritiva Foundation, and is an editor of the Journal of Cutaneous Medicine and Surgery.

EPISODE SUPPORTED BY CELLTRION CANADA

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

🎙️🇨🇦🇺🇸. Hands On, Gloves Off: Cross-Border Talk on Atopic Hand Eczema

We’re coming to you from the heart of Music City, Nashville 🎸 — but don’t worry, this Cross-Border Talk is not about trade, tariffs, or hockey rivalries. This time, it’s all hands on deck. ✋🇨🇦🇺🇸

In this episode of the Skin and Joints Podcast from RAD 2026, our Cross-Border Dermatologist Faculty Dr. Raj Chovatiya from the U.S. joins Canadian favourite Dr. Melinda Gooderham for a lively, practical, and focused conversation on atopic hand eczema, chronic hand eczema, and fresh week 32 data exploring tralokinumab in this challenging and high-burden body site.

Hands may represent a small body surface area, but they carry an outsized burden. They are exposed, functional, visible, constantly irritated, and central to work, hobbies, caregiving, gardening, handshakes, procedures, and everyday life. 

In other words: when the hands are flaring, patients are not just uncomfortable — they are often functionally sidelined. 🧤🌱

This episode goes beyond the usual did the trial hit the endpoint discussion and digs into the real-world so what?

You’ll hear how the week 32 data may help frame expectations, why some patients may need more time before being labelled non-responders, how itch and pain improvements matter alongside clearance, and how shared decision-making can turn clinical trial endpoints into conversations patients actually understand. 📊🩺

The discussion also gets practical on where tralokinumab may fit alongside emerging topical options like delgocitinib, how to think about atopic hand eczema versus broader chronic hand eczema phenotypes, and why a back to basics approach remains timeless advice when patients are not responding as expected. 🔍

From Nashville notes to Monday morning clinic, this Cross-Border Talk offers a hands-on look at atopic hand eczema — with just enough clinical soil turned over to leave you wanting the full episode. 🎙️✋

Learning Objectives 🎯

After listening to this episode, listeners will be able to:

ABOUT Dr. Raj Chovatiya, MD, PhD, MSCI

Raj Chovatiya, MD, PhD, MSCI is Associate Professor at Rosalind Franklin University of Medicine and Science Chicago Medical School and Founder and Director of the Center for Medical Dermatology + Immunology Research in Chicago, Illinois. His clinical and research focus includes the intersection of cutaneous immunology and inflammatory disease. He received his MD and PhD in immunology from Yale and completed his residency, postdoctoral research fellowship, and MS in Clinical Investigation at Northwestern University where he also served as Chief Resident. Dr. Chovatiya has a particular interest in optimizing patient-centered care, understanding chronic disease burden especially in understudied inflammatory diseases, exploring health and social disparities, and improving care across diverse skin types. He has published numerous abstracts and manuscripts and has been nationally and internationally recognized for his contributions as a clinician, educator, researcher, and leader.

ABOUT Dr.Melinda Gooderham, MD, FRCPC ( Dermatology)

Toronto, ON

Melinda Gooderham MD MSc FRCPC Dr. Gooderham is a Dermatologist and Medical Director at the SKiN Centre for Dermatology and an Investigator with Probity Medical Research. She is an Assistant Professor at Queens University and a Consultant Physician at the Peterborough Regional Health Centre. She is a fellow of the Royal College of Physicians and Surgeons of Canada.

Dr. Gooderham has been the principal investigator for over 200 clinical trials and she practices with a focus on inflammatory diseases of the skin. She also contributes to several peer-reviewed dermatology publications as an associate editor, reviewer, and has been an author of 205 articles. She enjoys lecturing to global audiences on new therapies for skin diseases.

Episode supported by and IME Grant from LEO Pharma

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

🎙️ PART 1:  Real-World Biosimilar Care in HS with Dr. Lauren Lam and Dr. Marni Wiseman

HS has officially entered the Skin and Joints chat — and it did not come quietly.

In this special Part 1 episode, we welcome back two Skin and Joints Podcast Faculty favourites, dermatologists Dr. Lauren Lam and Dr. Marni Wiseman, for a practical, candid, and refreshingly real-world conversation on hidradenitis suppurativa, biologics, and the evolving role of biosimilars in Canadian care.

From delayed diagnosis and cumulative life-course impact to biologic timing, patient expectations, injection burden, access barriers, and the art of asking, “How sick of this are you?” — this episode digs into the clinical realities that do not always fit neatly into trial endpoints.

Dr. Lam and Dr. Wiseman share frontline insights on why HS is uniquely challenging, why earlier intervention may change the patient journey, and how biosimilars are reshaping access, dosing conversations, and practical treatment decisions. Expect clinical pearls, a few myth-busting moments, and clinic hot tips you can actually use — from identifying the right referral pathway, to setting realistic goals, minimizing injection burden, considering dose optimization, and translating trial endpoints into real-life wins for patients.

Also discussed: tennis dreams, cottage shade, citrate-free formulations, the joy of one injection instead of two, and why HS care is rarely a solo sport. 🎾🌿💉

After listening to this episode, learners should be able to:

#SkinAndJointsPodcast #HidradenitisSuppurativa #HSAwareness #Biosimilars #Adalimumab #Dermatology #RheumDerm #InflammatoryDisease #RealWorldEvidence #PatientCenteredCare #BiologicTherapy #CanadianDermatology #MedicalPodcast #ClinicianEducation #ClinicHotTips #AccessToCare

Episode supported by Celltrion Canada. 

 ABOUT Dr. Lauren Lam BScH, MD, FRCPC

​​Medical, Surgical & Cosmetic Dermatologist CALGARY, AB

Dr. Lam is the Vice President of the Canadian Hidradenitis Suppurativa Foundation and a Canadian Board Certified Dermatologist subspecializing in Hidradenitis Suppurativa Deroofing Procedures.  She runs a weekly deroofing clinic in Calgary, Alberta, and has done 1500+ cases to date.  

Besides collaborating on global HS projects, her other favourite endeavours include being an international explorer, culinary enthusiast and aunt to 5 dogs.

ABOUT Dr. Marni C. Wiseman MD FRCPC DABD

Associate Professor, Section Head Dermatology University of Manitoba

Director, SKiNWISE DERMATOLOGY and Wiseman Dermatology Research

Dr. Marni C. Wiseman began her Dermatology practice in Winnipeg, Manitoba in 2001.She is an Associate Professor and Section Head of Dermatology at the Faculty of Medicine at the University of Manitoba. Dr. Wiseman is the Medical Director of SKiNWISE DERMATOLOGY, where she conducts her private medical practice.  

Dr. Wiseman’s areas of clinical and research interest include inflammatory disease: psoriasis, atopic dermatitis, hidradenitis suppuritiva, vitiligo, alopecia areata, urticaria, and acne vulgaris.

Dr Wiseman is Principal Investigator at Wiseman Dermatology Research and has participated in hundreds of clinical trials and registry studies. Dr. Wiseman is a frequent lecturer at meetings and congresses nationally and internationally and is extensively published in areas of inflammatory skin disease, photodermatosis, and cutaneous malignancy. Dr. Wiseman is a supervisor and mentor for medical students and residents, conducts regular rural/remote outreach clinics, has significant volunteer involvement with the Canadian Dermatology Association, the Canadian Hidradenitis Suppuritiva Foundation, and is an editor of the Journal of Cutaneous Medicine and Surgery.

EPISODE SUPPORTED BY CELLTRION CANADA

📻www.skinandjoints.ca

✉️[email protected]

📻www.skinandjoints.ca

✉️[email protected]

In this final episode of our AAD 2026 atopic dermatitis post-game poster series, we’re joined by dermatologist Dr. Julien Ringuet from Quebec City for a practical, no-fluff breakdown of the JADE REAL analysis — and what flexible abrocitinib dosing may actually mean when Monday morning clinic rolls around.

Because in real life, patients do not always follow a tidy trial algorithm. Symptoms flare, itch keeps people up, adherence shifts, priorities change, and sometimes the “right” dose is less of a fixed destination and more of a GPS recalculating in real time. 🧭

Dr. Ringuet walks us through the clinical “so what” behind dose escalation and de-escalation, explaining why moving from 100 mg to 200 mg — or stepping down from 200 mg to 100 mg — should not automatically be seen as failure, overtreatment, or backpedalling. 

Instead, flexible dosing may be part of a thoughtful, shared decision-making strategy that better reflects the messy, dynamic reality of moderate-to-severe atopic dermatitis care.

We cover how early reassessment, patient-reported outcomes, itch, sleep, EASI trends, payer flexibility, and treat-to-target thinking all fit into the bigger picture. And yes, we also discuss the real-world art of knowing when to push, when to pause, and when to test the waters with a lower dose. 🌊

✨ Learning Objectives

By the end of this episode, listeners should be able to:

💡 Key Takeaway

Flexible dosing is not a loophole — it is real-world dermatology. The win is not finding one perfect pathway for every patient; it is learning how to reassess early, individualize thoughtfully, and adjust with purpose. 🩺

🎧 Tune in for practical pearls, real-world nuance, and Dr. Ringuet’s post-game analysis on what these data may mean for dermatologists managing AD in everyday practice.

#SkinAndJointsPodcast #AAD2026 #AtopicDermatitis #EczemaCare #Dermatology #PatientReportedOutcomes #JAKInhibitors #abrocitinib  #DermatologyEducation #MedicalEducation #HCPeducation #TreatToTarget #InflammatorySkinDisease #ClinicalData #DermTwitter #MedEd #Vodcast #PodcastEpisode #AADDenver #JAK #JAKinhibitor

ABOUT Dr. Julien Ringuet

Dermatologist, Quebec City, QC

Dr Ringuet is a board certified dermatologist who practices in Quebec City as the principal investigator at the Centre de Recherche Dermatologique de Québec (CRDQ).

Supported by an IME Grant from PFIZER.

📻www.skinandjoints.ca

✉️[email protected]

Are We Treating Eczema… or Just Admiring Better Scores? Minimal Disease Activity in Atopic Dermatitis

In this rapid-fire AAD poster recap, dermatologist Dr. Julien Ringuet joins the Skin and Joints podcast to unpack a big idea with a small acronym: MDA — Minimal Disease Activity.

Borrowed from the rheumatology playbook and now making its way into dermatology, MDA asks a deceptively simple question in atopic dermatitis care: Is the patient actually doing well, or do they just look better on paper?

Together, we dive into new treat-to-target data from the AHEAD analysis, comparing abrocitinib and dupilumab through a more holistic lens — one that includes not only skin clearance, but also itch, sleep, quality of life, and the patient’s lived experience. Spoiler: an EASI score may be impressive, but it does not tuck your patient into bed at night.

Dr. Ringuet breaks down how MDA could help clinicians raise the bar in atopic dermatitis management, why early symptom relief matters, where oral JAK inhibitors may fit for selected patients, and why safety, comorbidities, route of administration, patient preference, and long-term strategy still deserve front-row seats in every treatment decision.

This episode is not just about picking a winner between therapies. It is about redefining what “success” should mean in chronic inflammatory skin disease — and avoiding the trap of accepting “better” when patients are still itchy, sleepless, and sidelined from daily life.

By the end of this episode, listeners will be able to:

Minimal Disease Activity may be the dermatology upgrade we did not know we needed: less “your skin looks better” and more “are you sleeping, functioning, and living better?”

#SkinAndJointsPodcast #AAD2026 #AtopicDermatitis #EczemaCare #Dermatology #PatientReportedOutcomes #JAKInhibitors #abrocitinib  #DermatologyEducation #MedicalEducation #HCPeducation #TreatToTarget #InflammatorySkinDisease #ClinicalData #DermTwitter #MedEd #Vodcast #PodcastEpisode #AADDenver #JAK #JAKinhibitor

ABOUT Dr. Julien Ringuet

Dermatologist, Quebec City, QC

Dr Ringuet is a board certified dermatologist who practices in Quebec City as the principal investigator at the Centre de Recherche Dermatologique de Québec (CRDQ).

Supported by an IME Grant from PFIZER.

📻www.skinandjoints.ca

✉️[email protected]

JAKs, Flares & Rescue Plans:  The Art of the Atopic Dermatitis Dose-Down 🎙️

In this rapid-fire post-AAD recap, dermatologist Faculty Dr. Julien Ringuet joins the Skin and Joints Podcast to tackle a question that comes up all the time in real-world atopic dermatitis care: once a patient is doing well, can we safely step down therapy without sending their skin into rebellion?

Using newly presented data on abrocitinib dose down-titration from the JADE program, Dr. Ringuet walks through what happens when patients who respond to 200 mg transition to 100 mg for long-term maintenance—and what clinicians should do if disease control starts to slip. Spoiler: stepping down is not a cliff dive. 

Along the way, we cover the “so what?” behind the numbers: who may be a good candidate for dose reduction, how to define loss of control beyond just visible skin lesions, why itch and sleep still deserve centre stage, and how shared decision-making can turn a dosing conversation into a true treatment partnership.

This episode is for clinicians who want to move beyond poster reading and into practical, exam-room-ready conversations about JAK inhibitors, maintenance dosing, treat-to-target thinking, flare management, and individualized care in atopic dermatitis.

Learning Objectives 📚

After listening to this episode, listeners should be able to:

#SkinAndJointsPodcast #AAD2026 #AtopicDermatitis #EczemaCare #Dermatology #PatientReportedOutcomes #JAKInhibitors #abrocitinib  #DermatologyEducation #MedicalEducation #HCPeducation #TreatToTarget #InflammatorySkinDisease #ClinicalData #DermTwitter #MedEd #Vodcast #PodcastEpisode #AADDenver #JAK #JAKinhibitor

ABOUT Dr. Julien Ringuet 

Dermatologist, Quebec City, QC

Dr Ringuet is a board certified dermatologist who practices in Quebec City as the principal investigator at the Centre de Recherche Dermatologique de Québec (CRDQ).

Supported by an IME Grant from PFIZER.

📻www.skinandjoints.ca

✉️[email protected]