Smallpox is a pathogen specific to our species and it has wreaked havoc with human populations over the centuries. Ultimately it gave rise to what we now think of as immunisation and vaccine technology and is the only disease we have ever eradicated.

In this episode we explore this epic history of the Variola virus with Professor Gareth Williams, hear from Dr Celine Gounder, who sought out and interviewed the last survivor of smallpox in the wild, and confront a still controversial predicament: should all remaining live samples of the smallpox virus be destroyed? with Professor David Heymann.

Featured guests:

Prof. Gareth Williams, author of 'Angel of Death: The Story of Smallpox' - on the history of smallpox https://thesohoagency.co.uk/authors/gareth-williams/

Dr. Celine Gounder on Rahima Braha the last survivor of smallpox in the wild https://www.celinegounder.com/

Professor David Heymann on the eradication of wild smallpox and the argument for retaining live virus samples for research https://www.lshtm.ac.uk/aboutus/people/heymann.david