The Nov. 24th deadline is fast approaching, and the Iran nuclear talks are going down to the wire.  Host Nina Easton talks with Danielle Pletka, Senior Vice President, Foreign and Defense Policy Studies at the American Enterprise Institute (AEI) about the negotiations and whether an agreement is likely.

Republicans will take charge of the House and Senate in January.  Dr. Kathleen Hicks, CSIS Senior Vice President, Henry Kissinger Chair, and Director of the International Security Program, and Dr. Elaine Kamarck, Senior Fellow, Governance Studies Program at Brookings and Founding Director of the Center for Effective Public Management, discuss the likely impact on the fight against ISIS, the Defense Dept. budget, and trade deals with Europe and Asia.

Brazil’s president gets a second term but faces a politically divided country that’s now technically in recession. Cassia Carvalho, Brazil-U.S. Business Council Executive Director and CSIS Americas Program Senior Associate, and Dr. Julia Sweig, Director of Latin America studies and the Global Brazil Initiative at the Council on Foreign Relations, discuss the challenges Pres. Dilma Rousseff must tackle.

According to the UN, sexual exploitation and forced labor are the most common forms of human trafficking.  Dr. Sarah Mendelson, director of the CSIS Human Rights Initiative and Holly Burkhalter of the International Justice Mission discuss this global problem and the policies needed to address it.

State Dept. Ebola Coordinator Amb. Nancy Powell discusses calls for a travel ban, training for U.S. military troops heading to West Africa, and why the end of the rainy season in Ebola-affected regions may mean even more cases.

What really drives this 21st century czar? Our experts weigh in on the history and personality of a man intent on defying the West.

U.S. Secretary of Commerce Penny Pritzker discusses her recent trade and investment trip to Ukraine, Poland, and Turkey with members of President’s Export Council and how “commercial diplomacy” can be an effective and strategic tool for the U.S. government. She talks about Ukraine’s struggle to fight corruption and build business as well as the low number of women in Turkey’s labor force. Amy Studdart, Deputy Director and Fellow of the William E. Simon Chair in Political Economy at CSIS, provides insights on the Ukraine economic “backstory.” Read Nina Easton’s profile of Secretary Pritzker at trade and investment trip to Ukraine.

Nina Easton, Fortune Magazine Senior Editor and Washington Columnist, Chair, Fortune Most Powerful Women International Summit, and CSIS Senior Fellow, moderates a discussion of ISIS and the U.S. military strikes on Iraq and Syria. The roundtable includes Dr. Kathleen Hicks, Senior Vice President, Henry A. Kissinger Chair, and director of the International Security Program at CSIS. Heather Conley, Senior Vice President for Europe, Eurasia, and the Arctic, and director of the Europe Program at CSIS, and Stephanie Sanok Kostro, Senior Fellow, International Security Program at CSIS.