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Snack: The Catalysis Laboratory at Merck - 20 Years of Catalyzing Innovation (Part 2)
L.-C. and Dani talk about the next era in the Catalysis Lab's evolution, highlighting the democratization of high-throughput experimentation tools for end-users and the development of nanomole-scale HTE. It was also in this period that the Catalysis Laboratory's expanded its capabilities in photochemistry developing screening tools to invent and scale-up novel photochemical synthetic methods, including decatungstate mediate reactions and photoredox catalysis.
Read the paper we discussed today here:
The Catalysis Laboratory at Merck: 20 Years of Catalyzing Innovation - ACS Catalysis
Nanomole-scale high-throughput chemistry for the synthesis of complex molecules - Science
Enantioselective Synthesis of Hemiaminals via Pd-Catalyzed C–N Coupling with Chiral Bisphosphine Mono-oxides - JACS
A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions - Chemical Science
Development of a Direct Photocatalytic C–H Fluorination for the Preparative Synthesis of Odanacatib - Organic Letters
Follow the Pharm to Table podcast on Twitter - @PharmtoTablePod
Visit our website at https://anchor.fm/pharm-to-table
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By LC Campeau, Dani SchultzL.-C. and Dani talk about the next era in the Catalysis Lab's evolution, highlighting the democratization of high-throughput experimentation tools for end-users and the development of nanomole-scale HTE. It was also in this period that the Catalysis Laboratory's expanded its capabilities in photochemistry developing screening tools to invent and scale-up novel photochemical synthetic methods, including decatungstate mediate reactions and photoredox catalysis.
Read the paper we discussed today here:
The Catalysis Laboratory at Merck: 20 Years of Catalyzing Innovation - ACS Catalysis
Nanomole-scale high-throughput chemistry for the synthesis of complex molecules - Science
Enantioselective Synthesis of Hemiaminals via Pd-Catalyzed C–N Coupling with Chiral Bisphosphine Mono-oxides - JACS
A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions - Chemical Science
Development of a Direct Photocatalytic C–H Fluorination for the Preparative Synthesis of Odanacatib - Organic Letters
Follow the Pharm to Table podcast on Twitter - @PharmtoTablePod
Visit our website at https://anchor.fm/pharm-to-table