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SUMMARY: Development of Ideas in Neuroscience; creativity; reasoning types;

SUMMARY: Lecture given for Lifetime Service Award in Neurosurgery; 5th Shaolin Congress; Henan Provincial Hospital, Henan China 6/1/2023; Is there a BBB in Brain Tumors; Is EC-IC Bypass good for Cerebral Ischemia: Fact or Fiction?; Coiling for Aneurysms-The end of surgical. treatment; VBI-An underdiagnosed and treated disease; First interventional Treatment of Basilar thrombosis; 40 yrs ago-Intracranial Vascular grafting; How to solve the Brain Drain: International Fellowship Program; Nurse practitioners; 24-hr visiting hours for patient's family in room or ICU; SNI - Free journal to all; SNI Digital 3D future of communication; Space and universe thoughts. "The Patient Comes First"- no exception! (JIA)

Summary: Excellent video of Neuroendoscopic approach to the posterior third ventricle using the transchoroidal route. 6 minutes; Subtitles only, no verbal audio.

SUMMARY: This 2 1/2 hour meeting demonstrates the work of 9 YNSS under medical doctor supervision on neurological neurosurgical topics. Invited neurosurgeon and neurologist experts provide perspective and comments and the significance of these projects. The topics range from early work in the Sonodynamic ultrasound treatment of glioblastomas, reversing immuno-supression of glioblastomas; pediatric meningiomas, comparative approaches tuberculum sella meningiomas, comparative treatments for Cartoid stenosis and the new trans carotid interventional route; treatment of post stroke cognitive deficits; analysis of robotic surgery technology in neurosurgery; post-operative pain treatment; and drug treatment for Alzheimers Disease.

Authors Summary: "Neurons derived from human induced pluripotent stem cells (iPSCs), named induce neurons (iNs) are recently being used to screen therapeutic candidates for Alzheimer’s disease (AD). Kondo et al. screened a library of 1280 drugs approved by the Food and Drug Administration (FDA) in America against AD patient-derived iNs and identified bromocriptine as having the most potent anti-Aβ effect for AD patients with mutations in the presenilin 1 (PSEN1) gene1. This study aimed to compare the effect of bromocriptine and four other Alzheimer’s disease-indicated drugs on iNs generated from AD patient-derived iPSCs using immunofluorescence staining."

The authors concluded from their study that "The post-operative analgesic management of the majority of patients in the INS follows current guideline recommendations. Where guidelines were not followed, this was most commonly due to co-prescription of weak and strong opioids and inaccuracies in pain score documentation. Regular re-education and emphasis on the importance of available guidance may reduce these errors. Earlier referrals to acute pain services will be beneficial in the management of complex patients." The discussion of periopertive pain management is informative for neurologists and neurosurgeons.-JIA

SUMMARY;

The authors reviewed the literature on the newer endoscopic removal of Tuberculum sella meningiomas and compared the outcomes with traditional transcranial route, the keyhole transcranial, superior interhemispheric, transfalcine approach. Are the studies and results comparable? There is less reported experience with the endonasal route. The incidence of CSF leak is higher in the endonasal approach. Which procedure is the best? You decide.

SUMMARY: Dr. Patel is an Associate Professor at the University of Texas Southwestern Medical Center, Dallas, Texas and presents a global overview of the advances in surgical, pharmacological, and other treatments for tumors of the Central Nervous System. A State-of-the -Art Lecture on Neuro-oncology