What if psychedelics could transform the way we treat trauma, chronic pain, and insomnia? This week, neuroscientist and psychedelic researcher Grace Blest-Hopley joins the show to break down the research on psychedelics and female biology. She discusses how psychedelics work in the brain, and the ways that psychedelic-assisted therapies might be beneficial for women in midlife.

Links to resources mentioned in this episode:

Hystelica’s resources on psychedelic retreats

The Heroic Hearts Project

Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics

Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings

The acute effects of classic psychedelics on memory in humans

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Johns Hopkins study on psychedelics and Alzheimer’s

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

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Maya Shankar, host of Pushkin's A Slight Change of Plans podcast, just released a new book, "The Other Side of Change". To celebrate, we're sharing an exclusive excerpt with the Pushkin community. It's about what first sparked Maya’s interest in change, and the story of a woman named Olivia Lewis.

Order “The Other Side of Change: Who We Become When Life Makes Other Plans” at changewithmaya.com/book, or wherever you like to buy books.

About The Other Side of Change:
Life has a way of thwarting our best-laid plans. Out of nowhere, we’re confronting the end of a relationship, an unexpected diagnosis, the loss of a job, or some other twist of fate. In these moments, it can feel like we’re free-falling into the unknown.

As a cognitive scientist, Maya Shankar has spent decades studying the human mind. When an unwanted change in her own life left her reeling, she sought out people who had navigated major disruptions. In "The Other Side of Change", Shankar tells their riveting, singular stories and weaves in scientific insights to illuminate universal lessons hidden within them.

When a big change happens to us, it can lead to profound change within us. The unique stresses and demands of being thrust into a new reality can lead us to uncover new abilities, perspectives, and values, transforming us in extraordinary ways. What if we saw moments of upheaval as an opportunity to reimagine who we can be, rather than as something to just endure? Whether you’re processing a past change, grappling with a present one, or bracing for a future one, this book is a wise and thought-provoking companion to help you discover who you can become on the other side of change.

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Malcolm Gladwell sits down with IBM Chairman and CEO Arvind Krishna in a special live episode of Smart Talks with IBM. They discuss the groundbreaking potential of quantum computing, the transformative impact of AI on business, and how Krishna’s visionary predictions from the 90s continue to guide IBM’s innovations.

This is a paid advertisement from IBM. The conversations on this podcast don't necessarily represent IBM's positions, strategies or opinions.

Visit us at https://www.ibm.com/think/podcasts/smart-talks

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According to the science, it really is better to give than receive. Donating a dollar; sharing a kind word or lending someone a hand changes lives, but can also hugely boost your happiness. So we're teaming up with other podcasts from Hidden Brain to Revisionist History to ask you to give to a charity helping some of the poorest people around. We're calling it #PodsFightPoverty.     

Go to givedirectly.org/happinesslab right now and give whatever you can. And the first $500,000 we donate will be matched thanks to our friends at Giving Multiplier!

Even a small donation will make you feel good and have a much larger impact on the world than you thought possible. To help inspire you, this special episode examines the science of giving and shares stories of heartwarming and impactful acts of kindness.   

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Thomas Alva Edison helped transform America and the world. He registered over one thousand patents before he died in 1931 - and we can thank him for advances in electric power, communications technology, music recording and even the movies. But his biggest breakthrough doesn't get nearly enough attention. 

In many ways, Edison invented modern inventing. Join Business History hosts Jacob Goldstein and Robert Smith as they trace the life story of a scrappy young boy with bad hearing who almost singlehandedly invented R&D.     

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When Michael Lewis wrote The Big Short, there was an extra character in the story: The Federal Reserve System, the central bank of the US, which bought up bad debt on the balance sheets of big Wall Street banks and trading firms. To better understand the Fed’s role in the financial crisis of 2008, Michael turns to UC Berkeley economics professor Emi Nakamura. And in the process, we get a master class in how currency works, and why there’s still some gold in the vaults of the Fed.

For more, check out Emi Nakamura’s Macro Policy Lab.

Order The Big Short audiobook, now narrated by Michael Lewis, on Audible, Spotify, pushkin.fm/bigshort or wherever you get audiobooks.

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For Breast Cancer Awareness Month, Dr. Susan Domchek joins the show to talk about the importance of knowing your genetic history, using genetic testing to understand cancer risk, and what you can do if you learn that you have BRCA gene mutation.

Links to resources mentioned in this episode:

Basser Center for BRCA

National Society of Genetic Counselors

National Comprehensive Cancer Network

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

See omnystudio.com/listener for privacy information.

Here's a preview of a podcast we think you'll enjoy. It's from the new season of Malcolm Gladwell's Revisionist History podcast, The Alabama Murders. Florence, Alabama. 1988. A preacher has an affair. A woman is murdered. One death cascades into more, stretching across decades and leaving no one untouched — victims, bystanders, perpetrators, and those just trying to help. Eventually, the consequences lead to the center of a hot national debate on who should be allowed to live, who should die, and how the state should kill them. On The Alabama Murders, Malcolm asks: why, in our efforts to alleviate suffering, do we so often make it worse? Find Revisionist History: The Alabama Murders wherever you get podcasts.

Get early, ad-free access to the full season of The Alabama Murders by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin shows.

Subscribe on Apple: apple.co/pushkin
Subscribe on Pushkin: pushkin.com/plus

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We're sharing a preview of College Matters from The Chronicle, a podcast from The Chronicle of Higher Education. After 16 months in a federal prison camp, William (Rick) Singer has had time to reflect on his role as the architect of a college-admissions bribery scheme that became known as Varsity Blues. The college consultant has apologized for concocting a plot that helped wealthy families, including some Hollywood celebrities, secure admission for their children to prestigious universities. But he isn’t slinking into the shadows. Singer says he’s already back in the consulting business. And he has come out of prison swinging, blasting the FBI, the college-admissions system, and anyone who might question the credentials of the students he represented.

Related Reading:
‘It’s an Aristocracy’: What the Admissions-Bribery Scandal Has Exposed About Class on Campus (The Chronicle) 

Higher Ed’s Bribery Scandal Is Decadent and Depraved. Here Are 8 Truly Tasteless Allegations (The Chronicle) 

We, the Privileged Parents That Matter, Applaud the Netflix College-Admissions Scandal Doc (The Chronicle) 

Admission Through the ‘Side Door’ (The Chronicle)

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Here’s a preview from another Pushkin podcast, Fiasco. Slow Burn co-creator Leon Neyfakh transports listeners into the reality of America’s most pivotal historical events, bringing life to the forgotten twists and turns of the past while shedding light on the present. In his new season, Leon looks at the 2012 Benghazi attack that left four Americans dead—and the ensuing political storm, which raised questions about America’s role in the world, established a playbook to weaponize attention in the social media age, and ultimately changed the course of U.S. history. Find Fiasco: Benghazi wherever you get podcasts and binge the entire season with a Pushkin+ subscription.

Sign up on the Fiasco Apple Podcasts show page or at pushkin.fm/plus.

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