Scientific Advisor Mike Templin joins us to discuss what drug developers have learned from working with the FDA during the pandemic. Where can we improve the relationship between science and government regulations? Find out now by listening to this episode. 

In honor of Rare Disease Month, we are joined by Terry Pirovolakis from CureSPG50.org. Terry's son Michael was born with the ultra-rare SPG50 disease. Listen now to hear their story.

Yugal Sharma, Ph.D., from CAS and David Clark, Ph.D., from Charles River join us to discuss machine learning in chemistry. We discuss the importance of organizing big data to avoid creating a data dump, and how machine learning can speed up drug discovery. 

Antonio Maltese, a senior studying political science in Virginia, is passionate about advocating for the rare disease community. He belongs to the community himself twice over, with a diagnosis of Huntington’s Disease and osteonecrosis. He speaks with Charles River scientists Lauren Black and David Fisher about his studies, their research, and how scientists and patients can help each other. 

Simon Chapleo, an expert in plant metabolism, joins us to discuss agrochemical safety testing and the difficulties of cultivating banana plants in Scotland.

Gracie van Brunt – singer, songwriter, and rare disease survivor – joins us for a candid interview about her life, career, and experiences with growing up rare.

Foster Jordan knows a thing or two about horseshoe crabs, and isn't afraid to share his opinion! Listen now to learn about the future of endotoxin testing, and the potential pitfalls of recombinant technology.

With chimeric antigen receptor T-cell (CAR T) therapy, patients’ own immune cells can be “souped up” and used as a cancer treatment. This immunotherapy and its variants are a promising area of research, with fascinating safety considerations. Listen now to learn about CAR T and TCR T from Sanne Holt, a biologist at Charles River.