In this exclusive podcast interview, Denise Holt sits down with Brett Kagan, Chief Scientist at Cortical Labs, for an in-depth exploration into their groundbreaking synthetic biological intelligence (SBI) technology. Brett reveals the science behind their revolutionary CL1 system—the first commercial biological computer fusing live human neurons with silicon computing. We discuss how their DishBrain experiment validated Dr. Karl Friston's Free Energy Principle, the extraordinary energy efficiency of biological intelligence, and the significant implications for industries like drug discovery, personalized medicine, and robotics. Don't miss this insightful conversation, rich with first-hand stories and detailed explanations from the forefront of neuroscience and AI innovation. #CorticalLabs #CL1 #ActiveInferenceAI

Key Topics:

·  The CL1 System: How Cortical Labs successfully merged live human neurons with silicon chips to create the first synthetic biological intelligence computing system.

·  DishBrain Experiment: Insights into the groundbreaking experiment validating Dr. Karl Friston's Free Energy Principle through neuron-based Pong gameplay.

·  Energy Efficiency of Biological Intelligence: Understanding how biological neurons provide vastly superior energy efficiency compared to traditional AI systems.

·  Ethical Implications: Brett Kagan's candid discussion on the responsible use of human neurons in research and their potential to reduce animal testing.

·  Real-world Applications: The transformative impact of synthetic biological intelligence on drug discovery, personalized medicine, and robotics.

Guest:Brett Kagan, Chief Scientific Officer at Cortical Labs
Host: Denise Holt, CEO and Founder, AIX Global Media

Huge thank you to Brettfor being on our show!

Discover more about Cortical Labs: https://corticallabs.com

Looking for education resources and courses on Active Inference, the Free Energy Principle, and Spatial Web Technologies? Visit Learning Lab Central to find others around the world who are just as excited for this new shift in AI and computing:

https://learninglab.emmersionpublishing.com

#CorticalLabs #CL1 #FreeEnergyPrinciple#ActiveInferenceAi

In this special episode of the Spatial Web AI Podcast,Denise Holt reconnects with Katryna Dow, CEO and Founder of Meeco, exactly 10years after their first conversation on Denise's earlier podcast, CollaborativeIQ. That original episode, "Let's Talk: Retaining Ownership of YourPersonal Data | Interview: Katryna Dow of Meeco," aired on March 31, 2015,and addressed early concerns about data privacy and individual data ownership.#dataprivacy #SpatialWeb

A decade later, Katryna, one of the earliest pioneerstackling data privacy and personal digital identity, reflects on how herinitial warnings about data misuse have unfolded and intensified. Having foreshadowedevents like the Cambridge Analytica scandal years ahead of time, she now highlightstechnological advances and shifts toward decentralized systems, the criticalrole of cryptography, decentralized identity, zero-trust architectures, and howthese elements are reshaping our digital lives. Katryna also shares recentmilestones at Meeco, including impactful collaborations across Europe,Australia, and Japan, and explores the emerging implications of AI, digitaltwinning, and the Spatial Web Protocol for privacy, trust, and secure digitalinteractions.

Join this timely discussion to gain valuable insights intohow far we've come, the evolving challenges of data privacy, and the essentialsteps toward building a secure, transparent, and user-controlled digitalfuture.

As a bonus to those who are curious about what we werediscussing ten years ago, the audio of the original interview is attached tothe end of our current conversation.

Topics Covered:

Evolution of Data Privacy (2015-2025)

Transitioning from Centralized toDecentralized Architectures

AI, Digital Identity, and PredictiveAnalytics

Regulatory Impacts: GDPR, EU DigitalIdentity, and Global Developments

The Role of Emerging Technologies andthe Spatial Web Protocol

Trust, Transparency, and DigitalEthics in the Next Decade

Guest: Katryna Dow, CEO and Founder of Meeco
Host: Denise Holt, CEO and Founder, AIX Global Media

Huge thank you to Katrynafor being on our show!

Katryna Dow onLinkedIn: https://www.linkedin.com/in/katrynadow/

Tolearn more about data privacy infrastructure, visit Meeco at https://www.meeco.me/

To find out moreabout Learning Lab Central and education and courses offered on ActiveInference AI and Spatial Web Technologies, visit:

https://emmersionpublishing.com/

To find others aroundthe world who are just as excited for this new shift in AI and computing, visitLearning Lab Central community platform:

https://learninglab.emmersionpublishing.com

#dataprivacy #SpatialWeb #Decentralization

January 28, 2025 - In this episode of the Spatial Web AI Podcast, titled "Active Inference AI - The AI Paradigm Shift Dr. David Bray, PhD Wants You to Know About," host Denise Holt engages in a thought-provoking conversation with Dr. David Bray, a distinguished figure renowned for his deep understanding of technology and geopolitics.

Dr. Bray, heralded as one of the 24 Americans changing the world by Business Insider and a former CIO of the FCC, shares his insights on the transformative potential of Active Inference AI. He contrasts this emerging technology with

Throughout the discussion, Dr. Bray articulates the necessity for a shift in our technological frameworks to accommodate the energy-efficient and adaptable capabilities of Active Inference AI. He emphasizes how this evolution in AI can enhance human agency and ensure the sustainability of societal advancements. Watch this episode to understand why Active Inference AI is not just a technological upgrade but a critical evolution for the integration of AI into our lives and societal structures.

Huge thank you to Dr. Bray for being on our show!

Dr. David Bray, PhD on LinkedIn: https://www.linkedin.com/in/dbray/

To find out more about Learning Lab Central and education and courses offered on Active Inference AI and Spatial Web Technologies, visit:

https://emmersionpublishing.com/

To find others around the world who are just as excited for this new shift in AI and computing, visit Learning Lab Central community platform:

https://learninglab.emmersionpublishing.com

#ActiveInferenceAI #SpatialWeb #KarlFriston 

The Spatial Web: A New Dimension of the Internet and a

In this exclusive interview and presentation, Denise Holt,

Denise explains how VERSES AI and the Spatial Web Foundation is leading the charge in this paradigm shift by developing and donating the protocol and IP for the Spatial Web to the IEEE, setting the stage for global adoption. This new AI, based on

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Find Denise Holt’s articles on her blog, and join our

Join the waitlist for our all new E-Learning courses for

https://aixglobalmedia.com/

#SpatialWeb #ActiveInferenceAI #HSML #DecentralizedAI

AI-ify's AI in Media & Entertainment Summit on June 2, 2024 wrapped up with a final panel that was so engaging to

The panel was hosted by Robert Scoble, and included panelists: Denise Holt, X. Eyeé, Eliza Tan, and Talbert Herndon

The discussion focused on the future of AI, AI safeguards, decentralized AI, the Spatial Web, Active Inference AI, and so much more.

HUGE thank you to Steven Echtman for facilitating this event and allowing it to unfold into the longest panel of the summit - giving voice to all the audience members who wanted to ask questions, and providing the space and time for such an important discussion on AI.

LinkedIn Links:

Steven Echtman: https://www.linkedin.com/in/stevene/

Robert Scoble: https://www.linkedin.com/in/scobleizer/

Denise Holt: https://www.linkedin.com/in/deniseholt1/

X. Eyeé: https://www.linkedin.com/in/techwithx/

Eliza Tan: https://www.linkedin.com/in/elizatan1/

Talbert Herndon: https://www.linkedin.com/in/talbert-andre/

AI-ify event information and links here:

Learn more about Active Inference AI and the Spatial Web on my blog here: https://deniseholt.us/

Join the Spatial Web AI Substack and find out how to tune into our exclusive invite-only monthly Learning Lab LIVE sessions here: https://deniseholt.substack.com/subscribe

AIX Global Media: https://aixglobalmedia.com

#ActiveInferenceAI #SpatialWeb #VERSESAI

Denise Holt speaking at AI-ify's AI in Media & Entertainment Summit on June 2, 2024, regarding how Active Inference AI and the Spatial Web are redefining media. #DecentralizedAI

HUGE thank you to Steven Echtman for inviting me to speak and participate in your event. You can find Steve on LinkedIn here: https://www.linkedin.com/in/stevene/

AI-ify event information and links here: https://aiify.io/events/20240601-02sf/

Learn more about Active Inference AI and the Spatial Web on my blog here: https://deniseholt.us/ Join the Spatial

AIX Global Media: https://aixglobalmedia.com

#ActiveInferenceAI

Spatial Web AI Knowledge Bank - Audio Narration of Denise Holt's article written January 10, 2024 - Ultimate Resource Guide for Active Inference AI. #ActiveInferenceAI #VERSESAI #KarlFriston

The Most Complete Repository of Research Links and Educational Content on the VERSES AI Technology & Active Inference AI

-- Get your copy of the Ultimate Resource Guide for Active Inference AI - Join my Substack Community and be sure to select one of the membership levels that include the guide!

Join here: https://deniseholt.substack.com/subscribe

Original Full Article here: https://deniseholt.us/the-ultimate-resource-guide-for-active-inference-ai-2024-q1

Want to learn more about Active Inference AI and the Spatial Web Protocol (HSTP & HSML)? Visit the Spatial Web AI website: https://deniseholt.us

Building amazing AI tools? Find out how to be spotlighted on our show: https://aixglobalmedia.com#ActiveInferenceAI #VERSESAI #HSML #HSTP #SpatialWeb

Spatial Web AI Knowledge Bank - Audio Narration of Denise Holt's article written January 1, 2024 - Hello 2024:   The Year Computing Changes Forever. #ActiveInference #VERSESAI #HSML

Join Spatial Web AI host Denise Holt  and Dr. John Henry Clippinger, co-founder of Bioform Labs and research scientist at MIT's Lab City Sciences group, and key figure behind the pivotal letter, "A Natural AI Based on The Science of Computational Physics, Biology and Neuroscience," shares his insights on the future of artificial intelligence. #ActiveInferenceAI #KarlFriston #VERSESAI

Dr. Clippinger discusses the importance of Active Inference,

Exploring societal impacts, Clippinger champions natural intelligence approaches over traditional Deep Learning models, emphasizing the importance of ethical considerations in human-machine interactions. With a focus on educational initiatives, he envisions a future where these principles drive positive change across fields, including addressing pressing global challenges like climate change, fostering safe AI as a public good and shaping a collaborative, inclusive future.

Tune in for all this and more…

Special

Connect

LinkedIn:

Connect with Denise:

Website: https://deniseholt.us/

Join the Spatial Web AI Substack Community: https://deniseholt.substack.com/subscribe

LinkedIn: https://www.linkedin.com/in/deniseholt1

#ActiveInference #NaturalAI

Join Spatial Web AI host Denise Holt, and Tim Scarfe, creator,

In this episode, they explore topics like Active Inference intelligent

Tim provides perspective on the need for ethical standards in AI research and development. Discussing issues surrounding data privacy, identity, and centralized control over information, they touch on issues of trustworthiness, transparency, and the challenges of governing exponentially advancing technologies. The conversation examines how social conditioning shapes human behavior and subjective experiences compared to machines.

They also contemplate future implications as brain-computer

Additional topics include memetics, decentralized decision-making, transhumanism, simulation theory, and the transition to a data-driven world powered by intelligence. How will hyperconnectivity impact our perception, identity, and fundamental cognitive abilities?

Tune in for all this and more…

Special thank you to Tim Scarfe for being on our show!

Connect with Tim:

LinkedIn:

Machine Learning Street Talk on YouTube: https://www.youtube.com/@MachineLearningStreetTalk

Connect with Denise:

Website: https://deniseholt.us/

LinkedIn: https://www.linkedin.com/in/deniseholt1

Join the Spatial Web AI Substack Community: https://deniseholt.substack.com/subscribe

#VERSESAI #SpatialComputing