Springer Nature

Genomics is about patterns, but finding them, or even knowing what to look for, is difficult. In this episode we talk to Noah Simon about the clever approaches he took to investigating the genomics of neuronal regeneration in mice.

The menstrual cycle is known to affect things like mood and changes in pain. But there can also be symptoms that have a serious impact on a person’s function, ability to work, ability to maintain friendships and romantic relationships. This is a rare condition known as premenstrual dysphoric disorder. But it’s not the only psychiatric condition that can worsen with changes in the menstrual cycle. For instance, nearly 60 percent of menstruating patients with depression can experience cyclical worsening similar to PMDD. Conditions such as these are generally referred to as menstrual cycle affective change. Menstrual cycle affective change is more common in those with chronic psychiatric disorders.

The authors are interested in reframing the conversation around menstrual cycle affective change to be something that is a more fundamental process that we can study across disorders, across categories, and identify biomarkers that might help us predict who's going to have those symptoms in more complex ways than we might be able to do with categories. This paper represents how can we take this dimensional way of thinking about menstrual cycle affective change and talk about the specific ways that we can be precise in looking at the time the time characteristics of that, the specific mechanisms, et cetera.

Tory Eisenlohr-Moul is an associate professor of psychiatry at the University of Illinois at Chicago in the department of psychiatry, and she’s one of the authors. Jordan Barone is an MD/PhD candidate at the University of Illinois at Chicago, and she’s another author.

In the final episode of this four-part series, Dr. Rebecca “Bek” Cooney, Chief Editor of Nature Mental Health, discusses the current publishing landscape and future of mental health research. She explores the balance between open access and subscription models through an equity lens, highlighting the importance of author-first and choice-driven perspectives. She also explains how the librarian’s role may shift in an increasingly open environment through heightened curation and direction for researchers. Last, Bek underscores mental health’s position as a “last frontier” by unpacking the obstacles that stigma creates, and how a more nuanced and widespread understanding of mental health can help overcome these barriers.

The forthcoming Nature Mental Health aims to build DEI principles into its editorial approach, thereby underpinning mental health as a human right. However, bringing these goals to fruition requires intentionality through inclusive initiatives and equitable publication practices—such as, global partnerships, lived experience advisory boards, and community-based recognition.

In the third episode of this four-part series, Chief Editor Dr. Rebecca “Bek” Cooney lays out how to put anti-racist and inclusive publishing ideals into practice. She highlights pledges as a solid jumping-off point, inviting transparency and accountability from readership. She also explains how publishers can ease the burden on contributors or reviewers through flexible deadlines and uncovering key pain points. Last, Bek discusses the shifting role of librarians as publishers face changes in data aggregation, content bundling, and open access policies.

While outlining the forthcoming journal Nature Mental Health, the editorial team wanted to build equity, awareness, and transparency into its framework. As Chief Editor Dr. Rebecca “Bek” Cooney notes, the journal’s scope underpins mental health as a human right in order to spotlight the lack of understanding and structural support for mental health issues. How can a journal intentionally establish itself as an advocate for mental health and social change?

In this second episode of the four-part series, Bek digs into equity in mental health. She highlights the difference between equity and equality in mental health programs—an “equal” approach doesn’t account for the racial, economic, and social discrepancies that impact care. In addition, Bek discusses the journal’s goal of including those with lived experiences and its positive effects on research quality. Further, she closes with strategies on how to go beyond goodwill gestures by encouraging dialogue among readership and ensuring transparency in editorial decisions around language and self-corrections.

In this first episode, Bek walks through her own editorial background and research interests in psychology. She explains what attracted her to the Chief Editor position and her hopes for the journal to expand upon traditional research in the field. Further, she provides an overview of Nature Mental Health’s inclusive editorial approach and the current prep work to prepare for the January launch.

The menstrual cycle is known to affect things like mood and changes in pain. But there can also be symptoms that have a serious impact on a person’s function, ability to work, ability to maintain friendships and romantic relationships. This is a rare condition known as premenstrual dysphoric disorder. But it’s not the only psychiatric condition that can worsen with changes in the menstrual cycle. For instance, nearly 60 percent of menstruating patients with depression can experience cyclical worsening similar to PMDD. Conditions such as these are generally referred to as menstrual cycle affective change. Menstrual cycle affective change is more common in those with chronic psychiatric disorders.

The authors are interested in reframing the conversation around menstrual cycle affective change to be something that is a more fundamental process that we can study across disorders, across categories, and identify biomarkers that might help us predict who's going to have those symptoms in more complex ways than we might be able to do with categories. This paper represents how can we take this dimensional way of thinking about menstrual cycle affective change and talk about the specific ways that we can be precise in looking at the time the time characteristics of that, the specific mechanisms, et cetera.

Tory Eisenlohr-Moul is an associate professor of psychiatry at the University of Illinois at Chicago in the department of psychiatry, and she’s one of the authors. Jordan Barone is an MD/PhD candidate at the University of Illinois at Chicago, and she’s another author.

This episode features a conversation with Senior Investigator Michael DeBaun, Professor of Pediatrics and Medicine at Vanderbilt University Medical Center, who has had a long career investigating the causes of and treatments for sickle cell anemia, and advocating for children and adults with this condition across the globe.

You can access his Vanderbilt page here: https://pediatrics.vumc.org/person/michael-r-debaun-md-mph#:~:text=Dr.,Syndrome%2C%20a%20cancer%20predisposition%20syndrome.

DNA sequence data promises to enable the study of biodiversity and its response to threats. However, much of this potential depends upon the availability of reference genomes. We hear about the European Reference Genome Atlas (ERGA) from its Chairperson, Rob Waterhouse (Swiss Institute of Bioinformatics). We also hear from ERGA member Will Nash (Earlham Institute) about his quest to understand the genome of the beautiful Violet carpenter bee.

In this episode, Geoff Marsh speaks to Dr. Stephanie Ford about our Collection on Fetal Alcohol Spectrum Disorder.

Access the full collection here: https://www.nature.com/collections/fccidiefbi