Explore groundbreaking advancements in treating hereditary angioedema with NTLA 2002, a revolutionary CRISPR-Cas9 therapy. Discover how this innovative one-time treatment significantly reduces attacks, offering hope for those affected by this rare condition. Original Article here.

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The ARTESIA trial demonstrates that Apixaban effectively reduces the risk of stroke or systemic embolism in patients with subclinical atrial fibrillation. Despite the increased risk of major bleeding, the severity of prevented stroke events outweighs the severity of bleeding events caused by the drug. This could potentially change the approach to managing subclinical atrial fibrillation in patients at high risk of stroke. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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This episode delves into a five-year study comparing the effectiveness of TAVR versus traditional surgery in treating low-risk aortic stenosis patients. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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We explore the groundbreaking trial of Amivantamab combined with chemotherapy in treating non-small-cell lung cancer - specifically those presenting the EGFR exon 20 insertions. We delve into the trial's promising results, the significant increase in progression-free survival, and the potential of this new approach to revolutionize lung cancer treatment. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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We discuss a clinical trial's findings on the use of intravenous levothyroxine on unstable, brain-dead heart donors, and how these findings may impact organ donation and transplantation practices. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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We delve into the results of the GRADUATE I and II trials, examining the impact of Gantenerumab, a human monoclonal antibody, on early Alzheimer's disease. We explore how its efficacy in reducing amyloid plaques failed to significantly alter the course of cognitive decline, while also discussing potential implications for future Alzheimer's disease treatments. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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The MINT trial compares liberal and restrictive transfusion strategies in patients with acute myocardial infarction and anemia. Findings suggest potential benefits of a liberal approach, prompting further research. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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Exploring the role of Elafibranor in Primary Biliary Cholangitis (PBC) treatment, this podcast delves into the significant findings of the ELATIVE trial, highlighting its potential as an effective and safe second-line treatment option for patients who have had inadequate responses or side effects with Ursodeoxycholic acid. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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We delve into the ORBITA-2 trial, examining the role of Percutaneous Coronary Intervention (PCI) in managing angina in patients with stable coronary artery disease. The trial results highlight PCI's effectiveness in reducing angina symptoms, compared to a placebo, in the absence of antianginal medication. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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We explore a groundbreaking study investigating the efficacy of botulinum toxin in treating essential or isolated head tremor. We delve into the details of the study's methodology, discuss its significant results, and examine the implications of these findings on future treatments for this common movement disorder. Original article here.

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The State of Health helps you understand the most important news and research in healthcare and medicine. For more visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠stateofhealth.care⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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