Episode breakdown:

00:00 – Intro: AI Meets Stroke Care
01:00 – Robert’s Journey from UCLA to Neurocritical Units
02:10 – Why Stroke is 30 Years Behind Cardiology
03:36 – Why Only 5–8% of Hospitals Use TCD
04:15 – How Stroke is Diagnosed Today (and Why It Fails)
05:28 – 80% of Strokes in Community Hospitals Have No Known Cause
07:16 – The Role of PFOs and Why TTE Misses Most of Them
10:15 – How Bubbles Reveal Stroke Risk Through the Brain
12:31 – How NeuraSignal’s Platform Automates Diagnosis
14:30 – Why 30% of Stroke Patients Miss the Treatment Window
15:47 – Robotics + AI + Ultrasound = Real-Time Stroke Insights
18:58 – Why Accessing the Skull Is So Complex (and How They Solved It)
20:37 – Weekly Cases Where NeuraSignal Prevented a Second Stroke
23:42 – What Happens After a PFO Is Found
24:53 – PFOs & Migraines: The Unlikely Connection
26:12 – The Bigger Vision: LVO, Cardiac OR, and Pre-Hospital Stroke Detection
29:01 – FDA Strategy: AI, Digital Biomarkers, and Future Indications
30:55 – Existing CPT Reimbursement Pathway & CMS Status
32:32 – Clinical Trials: Bubble, CommonSpirit, HCA & AHA Guidelines
34:39 – Stroke Care in 2030: What It Could Look Like with NeuraSignal
36:14 – Where to Meet NeuraSignal at Fall Conferences
37:40 – Clinical Adoption: From Academic to Community Hospitals
39:05 – How They Fit Seamlessly Into Stroke Workflows
40:50 – Making AI MedTech Accessible, Not Just Academic

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro: Ray Cohen’s MedTech Resume

02:21 – 44 Years, 0 BigCo Jobs: Ray’s Founding Philosophy

05:04 – How He Closed a $600M Deal Without an Investment Banker

08:05 – Why Relationships Matter More Than Bankers in M&A

11:19 – When Is the Right Time to Sell a MedTech Company?

13:44 – Why He Took Axonics Public *Before* FDA Approval

15:53 – $111M in Year 1 During COVID — How They Pulled It Off

17:42 – Why Most Commercialization Efforts Fail

19:19 – $230M IPO: How He Built the Case for Kestra’s Public Debut

22:36 – Turning Venture Dollars into a $1.2B Public Company

24:02 – The Founder’s Trap: Pivot or Persevere?

27:57 – How to Work with Strategics Without Giving Away the Deal

29:37 – Loyalty, Teams & Why Integrity Still Wins in MedTech

34:12 – Stop Worrying About Dilution. Raise More Than You Need.

35:43 – The $30M Fight Against Medtronic — And Why They Won

38:23 – The American Dream is Still Alive in MedTech

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Why This Episode Will Save Your Startup

01:25 – From Oracle to C3.ai: Bruce’s Operating + VC Journey

06:08 – What the VC World Doesn’t Tell Founders

10:47 – Why Most Startups Burn Cash After Raising

14:09 – The “Stadium” Metaphor: You Need a Category Before a Sales Team

18:06 – Creating the Enterprise AI Category at C3.ai

23:00 – SEO Hacks: Glossaries, Whitepapers, & Google Snippets

27:50 – Product-Market Fit Is Dead. Think Market-Product Fit

32:54 – Why Most Category Design Efforts Fail

39:30 – Why FDA Approval ≠ Market Readiness in MedTech

41:29 – Bruce’s Visual Traction Gap Map Explained

46:00 – MVP Is a Clock You Start—Too Early & You Lose

50:29 – MedTech Metrics: How ARR Maps to Repeatability

54:28 – How to Align Teams Across Phases Using Diagnostics

58:24 – Aligning Adoption Curve with Company Lifecycle

1:02:58 – The 76% Rule: Why Market Leaders Capture All the Value

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Why MedTech Still Fails Patients
03:19 – The Diagnosis Delay Crisis: Lung, Heart & Endometriosis
09:31 – Intuitive’s Vision: Redefining Outcomes Through Technology
12:01 – How Intuitive Measures Success: The Quintuple Aim
14:56 – Inside Intuitive’s Innovation & Startup Ecosystem
21:34 – From Mathematician to MedTech CEO: Gary’s Founder Journey
25:50 – Startup Grit: Navigating the AI River in Healthcare
29:16 – Leadership & Culture: What Drives Intuitive’s 97% Retention
32:33 – Mentorship in MedTech: How to Attract the Right Advisors
35:00 – Balancing Stakeholders: Patients, Hospitals, Investors
37:53 – AI in Healthcare: Signal vs. Hype, Pipes vs. Math
41:40 – Omar Khateeb asks how Intuitive Maintains a Culture of Disruption
48:22 – The Pivotal Pivot: From Cardiac to Urology & Global Scale
50:17 – Navigating Turbulent Times: Advice for Founders & VCs

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro: Meet Dr. Ameer Hassan & Quantanosis
01:45 – From Interventional Neurologist to Founder
04:00 – Global Stroke Access Crisis: The Mission Behind Quantosis
10:48 – The State of Mechanical Thrombectomy Innovation
12:58 – Fundraising $3M in One Day: How He Got Started
16:28 – What Is Histotripsy and Why It’s a Game-Changer for Stroke
19:13 – Risks of Current Stroke Devices: Endothelial Damage Explained
21:58 – The Future: Portable, AI-Powered Stroke Care in the Field
24:13 – Stroke Market Trends: U.S. vs Global CAGR
30:16 – Australia’s Hub-and-Spoke Model: Why It Works
32:35 – High-Risk Populations: Stroke and Atherosclerosis in Underserved Areas
35:35 – The Quantosis Device: Design, Use, and Treatment in 45 Seconds
38:30 – Using AI to Locate and Target Clots
39:45 – Breaking Through Bone: The IP That Makes It Work
41:45 – Regulatory Pathway: U.S. First-in-Human Strategy
44:25 – Series A Plans and What’s Next
46:45 – Where to Meet Quantanosis in 2025 (Conferences & Events)

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro: Why Knee Health Matters More Than You Think
01:59 – Meet Dr. Alan Reznik: Surgeon, Author, Engineer
04:29 – Anatomy 101: How the Knee Actually Works
09:46 – Why ACL Tears Are So Common (and How to Avoid Them)
13:16 – Cleats, Turf & the Injury Epidemic in Sports
16:36 – The Force Chain: Why Weak Hips Destroy Knees
21:16 – How a Kid Fixed His Shoulder by Training His Hips
23:46 – Squatting & Deadlifting: What’s Too Much Weight?
30:16 – Mobility vs Strength: Which Comes First?
32:46 – Joint Wear, Lubrication & Cartilage 101
38:16 – Reaction: Brian Johnson’s Anti-Aging Knee Workout
41:46 – Eccentric Training Explained (And Why It Works)
44:46 – The Nordic Curl Debate: Great or Dangerous?
48:46 – Why Your Supplements Might Not Be Helping
53:46 – When to Stop Therapy and See a Surgeon
58:46 – What Actually Rebuilds Cartilage?
01:04:46 – How to Know if Your Implant Surgeon Is Any Good
01:09:46 – Final Tips: Dr. Reznik’s “KNEES” Framework

Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro: Why April Was a Pivotal Month for Medtech

01:52 – Supira Medical Raises $120M for pVAD Innovation

05:34 – CMR Surgical’s $200M Robotics Bet

09:12 – Edwards Lifesciences Gets CE Mark for Sapien M3

13:01 – Biolinq’s $100M Needle-Free Glucose Monitor

15:27 – AI + Imaging: Anumana and Conavi Raise Big

18:40 – The Numbers: 3 Fastest-Growing Procedure Segments

21:45 – The APAC Expansion Opportunity for Medtech

24:15 – NAMSA, FDA, and the New Clinical-First Strategy

27:00 – Closing Thoughts: What to Watch Going into May

Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro: From NAMSA to MedSite Capital
01:52 – Who Is Ivanny Franklin? Her $B Exit Story
03:33 – Why She Started a Medtech Family Office
05:04 – MedSite’s Investment Strategy: SPVs, Syndicates, Direct
07:17 – Where She’s Investing: IVD, Cardiovascular, Health Tech
10:50 – How NAMSA’s Scale Gives Her Market Pattern Recognition
13:40 – Top Red Flags in Pitch Decks (Founders, Listen Up)

16:30 – 510(k) vs PMA: Why Your FDA Path Can Kill a Deal
18:55 – Clinical Trial Design: $1M vs $10M and What Drives It
20:50 – The Most Overlooked Statement in Regulatory Strategy
23:00 – Balancing Legacy with Risk: Family Office Real Talk
26:00 – Syndication as a De-Risking Strategy (Real Examples)
29:00 – How She Decides Between Direct vs Fund Investments
32:00 – Check Sizes, Stages, and How She Allocates
33:45 – Where Family Offices Actually Source Deals
35:45 – How Referrals, Ecosystems, and Events Drive Access
37:30 – Why Medtech Needs a “Family Office Network”
40:00 – The Conferences She Attends Year After Year
43:00 – AI in Medtech: Her Risk View & What She’ll Actually Back
45:00 – What Most Pitch Decks Are Missing (It’s Not What You Think)
48:00 – Why Clinician Feedback Is More Valuable Than Market Reports50:00 – Pre-FDA? You Still Need a Pipeline Strategy52:10 – Outside the Office: Travel, Horses, and E-Bikes53:30 – Final Thoughts: How Founders Win with the Right Support

Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 – Intro & What’s New in Pain02:00 – Turf Wars Are Over: Surgeons & Pain Docs Collaborating05:00 – Closed Loop for Peripheral Nervous System08:00 – Optogenetics & Viral Vector Therapy for Pain13:00 – New Tech Targets: Parkinson’s, Gait, Sleep Apnea16:00 – Imaging, Biomarkers & Functional MRI in Pain19:00 – Strategic Acquisitions: The Pros & Pitfalls24:00 – Device vs Pharma: The Real Long-Term Win30:00 – AI & Patient Selection: The Future of Tailored Pain Medicine35:00 – Why Physicians Struggle to Organize38:00 – IPOs & M&A Predictions for 202542:00 – How Startups Fail by Raising Too Much47:00 – NANDS, Non-Surgical Back Pain Study Highlights51:00 – Aspen Conference 2025: What to Expect54:00 – Closing: The Word of the Future is “Judgment”

Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.

Episode breakdown:

00:00 Introduction to Dr. Josh Makower and His Impact on MedTech
02:45 How Innovation Happens in Healthcare and Medical Devices
08:08 Why Reimbursement Reform Is Critical for MedTech Startups
08:49 Breaking Down the Complexities of Reimbursement Systems
12:10 How Medical Coding Affects Patient Access to Innovation
14:53 Challenges in Insurance Coverage and Healthcare Payments
17:58 How Regulatory Changes Influence Medical Innovation
20:48 Why Transparency Matters in Healthcare Reimbursement
24:10 Barriers Slowing Adoption of New Medical Technologies
26:48 Understanding the Economics Behind Healthcare Innovation
30:43 How to Create a Predictable Medical Coding Process
30:53 Overcoming Coverage and Insurance Challenges
32:50 The Role of Government in Healthcare Reimbursement Reform
36:13 Why Transparency Is Key to Driving Medical Innovation
37:58 Why Funding Medicare Is Essential for Better Patient Care
40:50 How to Accelerate Coverage for Breakthrough Technologies
42:30 How Coding, Coverage, and Payment Interact in MedTech
48:32 Rapid Fire: Josh Makower’s Insights and Personal Reflections

Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR

Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com

Are you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to GrowMyMedtech.com to book time for a free analysis.

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This podcast is for informational and educational purposes only and does not constitute financial, investment, legal, or medical advice. The views and opinions expressed by hosts and guests are their own and do not necessarily reflect those of State of MedTech LLC. Nothing discussed on this podcast should be interpreted as a recommendation to buy, sell, or hold any investment or security. Listeners should conduct their own due diligence and consult with a qualified financial advisor, attorney, or other professional before making any financial or investment decisions.