In this ASBMR 40th Anniversary Podcast episode, osteoporosis pioneer Dr. Stephen Cummings shares the stories behind some of the field’s most important advances. From the landmark Study of Osteoporotic Fractures (SOF) and the rise of bone densitometry to the origins of FRAX®, T-scores, osteopenia, and vertebral fracture assessment, Dr. Cummings reflects on the research that reshaped fracture prediction and osteoporosis care. He also offers valuable advice for the next generation on the importance of rigorous study design, innovation, and understanding the history behind today’s clinical practice.