In this ASBMR 40th Anniversary Podcast episode, osteoporosis pioneer Dr. Stephen Cummings shares the stories behind some of the field’s most important advances. From the landmark Study of Osteoporotic Fractures (SOF) and the rise of bone densitometry to the origins of FRAX®, T-scores, osteopenia, and vertebral fracture assessment, Dr. Cummings reflects on the research that reshaped fracture prediction and osteoporosis care. He also offers valuable advice for the next generation on the importance of rigorous study design, innovation, and understanding the history behind today’s clinical practice.

In this special episode celebrating the 40th anniversary of the Journal of Bone and Mineral Research (JBMR), host Dr. Christine Lary sits down with Dr. Sundeep Khosla, a renowned endocrinologist at the Mayo Clinic and one of the leading voices in osteoporosis and aging research.

With more than 35 years of experience, Dr. Khosla reflects on his remarkable career—from his early training at Mass General under influential mentors like Hank Cronenberg and Larry Riggs, to his groundbreaking discoveries that reshaped our understanding of bone biology. He discusses his pivotal work demonstrating the critical role of estrogen in male bone health, innovations in imaging bone microarchitecture, and his more recent research uncovering how cellular senescence contributes to age-related bone loss.

The conversation also explores the evolution of the field, including major technological advances, emerging therapies, and the expanding intersection between bone biology and aging science. Dr. Khosla shares insights from his long-standing relationship with JBMR and the American Society for Bone and Mineral Research, as well as lessons learned from decades of publishing, leadership, and collaboration.

Finally, he offers thoughtful advice for early-career researchers and clinicians—highlighting the importance of mentorship, intellectual curiosity, adaptability, and maintaining a “big picture” perspective in science.

This episode is both a retrospective on a distinguished career and an inspiring look ahead at the future of bone and mineral research.

In this JBMR at 40 anniversary episode, Natalie Sims, PhD speaks with Professor Ian Reid (University of Auckland), a leading figure whose work has helped define modern osteoporosis research and care.

Reid reflects on landmark contributions — from early bisphosphonate trials that reshaped treatment pathways to influential, and at times controversial, findings on calcium supplementation and cardiovascular risk. He also shares insights on the evolution of the field, the enduring impact of JBMR and ASBMR, and the importance of rigorous, evidence-based science.

With candor and perspective, Reid offers valuable guidance for the next generation: ask meaningful questions, design studies carefully, and have the courage to trust the data.

A thoughtful and celebratory look at four decades of progress through the lens of one of the field’s most impactful voices.

In this episode of JBMR at 40, host Matt Greenblatt sits down with Dr. Xu Cao of Johns Hopkins to explore a career defined by discovery across the bone field. Dr. Cao reflects on his pioneering work uncovering how osteoclasts and osteoblasts are coupled through TGF-β signaling—findings that reshaped our understanding of bone remodeling and seeded new insights into angiogenesis, pain, and osteoarthritis.

The conversation traces how seemingly distinct research areas converge on a central theme of coupling, extending from cellular biology to brain–bone communication. Dr. Cao also shares lessons from his time as a JBMR editor, advocating for a more multidisciplinary future that integrates biomechanics, neuroscience, and clinical perspectives.

Closing with candid advice for early-career scientists, he emphasizes hypothesis-driven thinking, resilience in lean funding climates, and the importance of curiosity in tackling the field’s biggest unanswered questions.

In this special anniversary episode of JBMR at 40, Dr. Emily Stein speaks with John P. Bilezikian, MD, a founding leader of the Journal of Bone and Mineral Research and one of the most influential figures in bone and mineral research.

Dr. Bilezikian reflects on his path into the field, his instrumental role in launching JBMR as the first Chair of the ASBMR Publications Committee, and the journal’s formative years alongside its inaugural Editor-in-Chief. He also discusses hallmark scientific contributions in parathyroid hormone biology, mentorship as a lasting legacy, and lessons learned from a career spanning decades of discovery, leadership, and global collaboration.

This episode offers a meaningful look back at JBMR’s origins—and a thoughtful perspective on the values that will guide its future.

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In celebration of the Journal of Bone and Mineral Research’s 40th anniversary, Associate Editor Nikki Partridge sits down with Dr. Paula Stern—former ASBMR president and the Society’s first woman president—to reflect on her pioneering career. Dr. Stern shares insights on the founding of JBMR, landmark discoveries in bone signaling and resorption, the power of mentorship, and her advice for the next generation of researchers in bone and mineral science.

As part of the Journal of Bone and Mineral Research’s year‑long 40th anniversary celebration, this special podcast episode features a conversation with Dr. Henry “Hank” Kronenberg, one of the most influential leaders in bone and mineral research. A longtime professor at Harvard Medical School and former chief of endocrinology at Massachusetts General Hospital, Dr. Kronenberg reflects on a career that helped shape modern understanding of parathyroid hormone signaling, bone development, and the use of genetic models in skeletal biology.

In this wide‑ranging interview, Dr. Kronenberg discusses the mentors and collaborations that guided his work, the evolution of the ASBMR and JBMR alongside his own career, and the lessons he’s learned as a clinician‑scientist and mentor. He closes with thoughtful advice for the next generation of researchers—on choosing important problems, embracing collaboration, and finding joy in discovery—making this episode both a celebration of the field’s past and an inspiring look toward its future.

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