As part of the Journal of Bone and Mineral Research (JBMR) 40th anniversary celebration, Natalie Sims, Ph.D. sits down with pioneering bone researcher Emeritus Professor Jack (TJ) Martin to explore the discoveries, collaborations, and scientific principles that helped shape modern bone biology. Widely recognized for his groundbreaking research, Martin reflects on a career that transformed understanding of skeletal physiology, from the discovery of parathyroid hormone-related protein (PTHrP) as the cause of humoral hypercalcemia of malignancy to the foundational work that paved the way for identifying the RANK/RANKL pathway, a central mechanism in bone remodeling.

Throughout the conversation, Martin shares stories of the mentors who influenced his journey, the curiosity and persistence that fueled major scientific breakthroughs, and the critical role of ASBMR and JBMR in advancing the field. He offers valuable insights into the importance of rigorous experimental design, independent thinking, and maintaining a healthy skepticism when interpreting scientific data.

This inspiring episode provides a fascinating look at the evolution of bone and mineral research through the eyes of one of its most influential leaders, while offering timeless advice for the next generation of investigators striving to make their own impact on science and medicine.

As part of the Journal of Bone and Mineral Research 40th Anniversary Celebration series, Pierre Moffatt, Ph.D. sits down with René St-Arnaud, Ph.D to honor the life, career, and enduring legacy of Francis H. Glorieux, M.D., Ph.D., one of the most influential figures in pediatric bone and mineral research.

From his early training in Belgium and groundbreaking work in Canada to his role as a visionary scientific leader, Dr. Glorieux helped transform the understanding and treatment of rare metabolic bone diseases, including X-linked hypophosphatemia, vitamin D deficiency rickets, and osteogenesis imperfecta. The conversation explores his remarkable scientific achievements, pioneering discoveries, and his unique ability to bridge basic science and clinical care to improve the lives of patients around the world.

Listeners will also gain insight into the determination and leadership that enabled Dr. Glorieux to build a world-renowned research program from modest beginnings, as well as his lasting impact as a mentor who launched the careers of generations of investigators. Beyond the laboratory, the episode reflects on his devotion to family, his passion for aviation and wine, and the personal qualities that made him such a respected and beloved figure.

Join us for a heartfelt tribute to a physician-scientist whose discoveries changed standards of care, whose mentorship shaped a field, and whose legacy continues through the patients, trainees, institutions, and scientific advances he inspired.

As part of the Journal of Bone and Mineral Research 40th Anniversary series, Associate Editor Nicola Partridge, PhD,  sits down with Dr. Clifford Rosen, former ASBMR President, renowned clinical endocrinologist, and pioneer in skeletal biology. Dr. Rosen reflects on the discoveries that shaped his career, including his groundbreaking work on bone marrow adiposity and its role in skeletal remodeling and metabolism.

In this candid conversation, he discusses the research findings that advanced the field, the mentors who influenced his scientific journey, the challenges of securing NIH funding, and the lessons he learned from setbacks. Dr. Rosen also shares his philosophy on mentorship, the importance of following the science wherever it leads, and the enduring value of collaboration and collegiality within the bone research community.

Looking ahead, he offers a message of optimism and persistence for the next generation of investigators navigating an increasingly challenging research landscape. Join us for an inspiring conversation with one of the field's most influential leaders as he reflects on four decades of discovery, mentorship, and service to bone and mineral research.

As part of the Journal of Bone and Mineral Research (JBMR) 40th Anniversary series, Marion Hannan sits down with renowned epidemiologist, past ASBMR President and longtime JBMR contributor Dr. Jane A. Cauley to reflect on a remarkable career dedicated to advancing bone and mineral research.

Dr. Cauley shares the pivotal discoveries that helped shape osteoporosis research, from landmark clinical trials and epidemiologic studies to groundbreaking work on estrogen, fracture prevention and health disparities. She also discusses the mentors who influenced her journey, her philosophy on mentoring the next generation of scientists and the importance of perseverance during challenging times for biomedical research.

With more than 160 publications in JBMR and decades of leadership within ASBMR, Dr. Cauley offers thoughtful insights on the enduring value of scientific collaboration, mentorship and curiosity—and why the Society's commitment to outstanding science continues to inspire researchers around the world.

Whether you're an early-career investigator or a longtime member of the bone and mineral research community, this conversation is a celebration of scientific discovery, mentorship and the lasting impact of a career devoted to improving musculoskeletal health.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this special episode celebrating the 40th anniversary of the Journal of Bone and Mineral Research (JBMR), host Ling Qin, MD, PhD, sits down with Brandon Lee, MD, PhD, Chair of the Department of Molecular and Human Genetics at Baylor College of Medicine and Director of the Center for Skeletal Medicine and Biology. Dr. Lee reflects on his remarkable career, from pioneering discoveries in skeletal genetics to advancing genomic medicine and translating rare disease research into life-changing therapies.

The conversation explores the evolution of skeletal biology over the past four decades, the power of human genetics to unlock new scientific insights, and the importance of mentorship, collaboration and embracing emerging technologies. Dr. Lee also shares the personal experiences and mentors that shaped his career, discusses the impact of ASBMR on the skeletal research community and offers inspiration for the next generation of physician-scientists.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this ASBMR 40th Anniversary Podcast episode, osteoporosis pioneer Dr. Stephen Cummings shares the stories behind some of the field’s most important advances. From the landmark Study of Osteoporotic Fractures (SOF) and the rise of bone densitometry to the origins of FRAX®, T-scores, osteopenia, and vertebral fracture assessment, Dr. Cummings reflects on the research that reshaped fracture prediction and osteoporosis care. He also offers valuable advice for the next generation on the importance of rigorous study design, innovation, and understanding the history behind today’s clinical practice.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this special episode celebrating the 40th anniversary of the Journal of Bone and Mineral Research (JBMR), host Dr. Christine Lary sits down with Dr. Sundeep Khosla, a renowned endocrinologist at the Mayo Clinic and one of the leading voices in osteoporosis and aging research.

With more than 35 years of experience, Dr. Khosla reflects on his remarkable career—from his early training at Mass General under influential mentors like Hank Cronenberg and Larry Riggs, to his groundbreaking discoveries that reshaped our understanding of bone biology. He discusses his pivotal work demonstrating the critical role of estrogen in male bone health, innovations in imaging bone microarchitecture, and his more recent research uncovering how cellular senescence contributes to age-related bone loss.

The conversation also explores the evolution of the field, including major technological advances, emerging therapies, and the expanding intersection between bone biology and aging science. Dr. Khosla shares insights from his long-standing relationship with JBMR and the American Society for Bone and Mineral Research, as well as lessons learned from decades of publishing, leadership, and collaboration.

Finally, he offers thoughtful advice for early-career researchers and clinicians—highlighting the importance of mentorship, intellectual curiosity, adaptability, and maintaining a “big picture” perspective in science.

This episode is both a retrospective on a distinguished career and an inspiring look ahead at the future of bone and mineral research.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this JBMR at 40 anniversary episode, Natalie Sims, PhD speaks with Professor Ian Reid (University of Auckland), a leading figure whose work has helped define modern osteoporosis research and care.

Reid reflects on landmark contributions — from early bisphosphonate trials that reshaped treatment pathways to influential, and at times controversial, findings on calcium supplementation and cardiovascular risk. He also shares insights on the evolution of the field, the enduring impact of JBMR and ASBMR, and the importance of rigorous, evidence-based science.

With candor and perspective, Reid offers valuable guidance for the next generation: ask meaningful questions, design studies carefully, and have the courage to trust the data.

A thoughtful and celebratory look at four decades of progress through the lens of one of the field’s most impactful voices.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this episode of JBMR at 40, host Matt Greenblatt sits down with Dr. Xu Cao of Johns Hopkins to explore a career defined by discovery across the bone field. Dr. Cao reflects on his pioneering work uncovering how osteoclasts and osteoblasts are coupled through TGF-β signaling—findings that reshaped our understanding of bone remodeling and seeded new insights into angiogenesis, pain, and osteoarthritis.

The conversation traces how seemingly distinct research areas converge on a central theme of coupling, extending from cellular biology to brain–bone communication. Dr. Cao also shares lessons from his time as a JBMR editor, advocating for a more multidisciplinary future that integrates biomechanics, neuroscience, and clinical perspectives.

Closing with candid advice for early-career scientists, he emphasizes hypothesis-driven thinking, resilience in lean funding climates, and the importance of curiosity in tackling the field’s biggest unanswered questions.

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.

In this special anniversary episode of JBMR at 40, Dr. Emily Stein speaks with John P. Bilezikian, MD, a founding leader of the Journal of Bone and Mineral Research and one of the most influential figures in bone and mineral research.

Dr. Bilezikian reflects on his path into the field, his instrumental role in launching JBMR as the first Chair of the ASBMR Publications Committee, and the journal’s formative years alongside its inaugural Editor-in-Chief. He also discusses hallmark scientific contributions in parathyroid hormone biology, mentorship as a lasting legacy, and lessons learned from a career spanning decades of discovery, leadership, and global collaboration.

This episode offers a meaningful look back at JBMR’s origins—and a thoughtful perspective on the values that will guide its future.

Watch on YouTube

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The views and opinions expressed by guests are their own and do not necessarily reflect the views or positions of ASBMR.