In episode 58, Rafael sits down with James Zanewicz, CEO of Connect, to discuss the art and science of building innovation ecosystems. From Connect's origins as the world's first accelerator to the future of AI-powered healthcare, James shares lessons from a career spanning science, law, technology transfer, academic medicine, and ecosystem development. Together, they explore what makes San Diego a global innovation hub, why collaboration matters more than competition, and how organizations can create the connective tissue that helps ideas become impactful.

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Episode 58 links:

• Connect

• Connect Current Podcast

• Alliance for AI in Healthcare

• BIO International Convention

• BLPN BIO Week Summit event

In this episode, Rafael Rosengarten sits down with Lisa Gurry, Chief Business Officer at GeneDx, to discuss the transformative role of genomic testing in rare disease diagnosis, therapeutic discovery, and precision medicine. Lisa shares GeneDx's mission to shorten the diagnostic odyssey for patients and families, explains how genomic data is accelerating drug development, and reflects on her deeply personal experience raising a daughter with a rare disease. Together, they explore how advances in sequencing, AI, and data integration are creating new possibilities for patients, clinicians, and biopharma alike.

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Episode 57 links:

• GeneDx
• GeneDx Infinity
• Truveta

In this episode, Rafael Rosengarten sits down with Dr. Kamal Jethwani, VP of Digital Ventures at Moffitt Cancer Center, CEO of AccelerOnc Studio, and consulting CEO of Decimal Health. With over two decades in digital health, Kamal shares how Moffitt is transforming cutting-edge oncology expertise into scalable AI-native companies, why operational implementation matters more than most founders realize, and how digital health adoption succeeds or fails inside real clinical workflows. From “concierge MVPs” to explainable AI, the conversation covers the hard-won lessons of building digital health programs at the ground level and why oncology innovation may be entering a completely new era.

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Episode 56 links:

• Moffitt Cancer Center
• AccelerOnc Studio
• Decimal Health

Precision oncology promises more data, more insight, and better decisions, yet in practice it often brings more complexity. In a new episode Rafael Rosengarten is joined by Dr. Shakti Ramkissoon, VP of Oncology at Labcorp, to unpack the realities on the ground. From access gaps, reimbursement challenges and fragmented workflows to the promise of longitudinal data and AI-enabled clarity, Dr. Ramkissoon shares how Labcorp is working to simplify complexity while preserving what matters most: human connection in care.

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Episode 55 links:

• Pulse of the Oncologist 2026 report
• Shakti Ramkissoon on LinkedIn

In this episode, Rafael Rosengarten speaks with Dr. Sean Khozin, CEO of the CEO Roundtable on Cancer. Sean shares how pre-competitive collaboration across industry, academia, and regulators is helping address some of the biggest challenges in oncology. The conversation explores the role of data sharing initiatives like Project Data Sphere, the promise of AI in clinical trials and discovery, and Sean’s unique journey from music to science.

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Episode 54 links:

• CEO Roundtable on Cancer
• Project Data Sphere
• Sean Khozin webpage
• PhyusionBio substack
• Sean Khozin on LinkedIn

In this episode, I’m joined by Colette Delawalla, founder and CEO of Stand Up For Science. What began as frustration over a federal “banned words” list evolved into a national mobilization effort to defend scientific freedom and evidence-based policymaking. We talk about the organization’s origin story, its National Day of Action on March 7, 2026, the communication gap in science on the political left, the campaign to impeach RFK Jr., and what rebuilding American science might require in the years ahead. Come on in and have a listen.

⁠⁠⁠TPM E53 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Episode 53 links:

• Stand Up For Science homepage 
• National Day of Action map (March 7, 2026)
• Impeach RFK Jr. & the Quack-o-gram campaign
• Articles of impeachment against RFK Jr.
• Stand Up For Science Subreddit
• Book recommendation: Nothing is True and Everything is Possible

In this episode, I’m joined by my longtime friend Ian Simon, Head of Biotechnology at Aspis Intelligence. Ian’s path runs from grad school vaccine research at Yale to senior roles at the White House, HHS, NIH, the State Department, and the Office of Long Covid. We talk about de-risking young biotech companies, what Covid taught us about science and public health, and how new technologies like AI might change how we do science altogether. 

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Episode 52 links:

• Ian Simon on LinkedIn
• Aspis Intelligence

In this episode Rafael sits down with Michelle Chen, President and CEO of Form Bio, a techbio company using AI to advance genome engineering and the development of genetic medicines. Michelle shares her zigzag journey from scientist to executive, how her team is tackling the biggest bottlenecks in gene therapy, and why AI has become essential in designing safer, more effective treatments.

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Episode 51 links:

• Michelle Chen on LinkedIn
• Form Bio

Today I’m joined by Mike Rossi, Vice President of Translational Science and Multi-modal Real-World Evidence Solutions at ConcertAI. Mike has built a career at the intersection of genomics, data science, and oncology, helping to bridge the gap between research and real-world clinical practice. We talk about what real-world data really means, how it becomes actionable evidence, and what it takes to turn the messy reality of patient care into insight that changes lives.

⁠⁠TPM E50 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Episode 50 links:

• Mike Rossi on LinkedIn
• ConcertAI

Joining us on this episode is Mida Pezeshkian, an old colleague and friend. Mida’s career has spanned from the depths of stem cell science as a student to her current focus on product management in healthcare. We talk about what it really takes to launch products in this space, and how she helps customers bring truly transformational innovations to market.

⁠⁠TPM E49 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Episode 49 links:

• Mida Pezeshkian on LinkedIn
• STEMA_cg
• The Lab