On today's episode, Dr Giovanni Adami (Verona, Italy) joins Dr Marwan Bukhari to discuss the association between environmental air pollution and rheumatoid arthritis flares.

Read the paper here: https://doi.org/10.1093/rheumatology/keab049

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Dr Marwan Bukhari (Royal Lancaster Infirmary, UK) and Prof. Maarten Boers (Amsterdam UMC, The Netherlands) join Dr Ai Lyn Tan to discuss the effects of glucocorticoids on bone health. Their observational data suggest that glucocorticoids do not have the detrimental impact on bone health that we have come to expect – a rather controversial finding indeed.

Read the paper: https://doi.org/10.1093/rap/rkab089

The GLORIA trial discussed is available here: https://ard.bmj.com/content/81/7/925

Thanks for listening to Talking Rheumatology Research! Join the conversation on X using #TalkingRheumResearch, tweet us @RheumJnl, or find us on Instagram and LinkedIn.

Want to read more rheumatology research? Explore Rheumatology and Rheumatology Advances in Practice.

Prof Richard Furie (New York, USA) and Dr Anastasia Madenidou evaluate the Phase 2, randomized, placebo-controlled trial of dapirolizumab pegol in patients with moderate-to-severe active systemic lupus erythematosus. They discuss the unique dose-response relationship endpoint used in this trial and the plans for Phase 3.

Read the paper here

Thanks for listening to Talking Rheumatology Research! Join the conversation on X using #TalkingRheumResearch, tweet us @RheumJnl, or find us on Instagram and LinkedIn.

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Dr Rishi Desai (Boston, USA) and Dr Marwan Bukhari discuss the risk of venous thromboembolism associated with tofacitinib in rheumatoid arthritis. Dr Desai’s recent paper used claims data to compare the risk of VTE with tofacitinib vs. TNFis. 

Read the paper here

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Dr Lihi Eder (Toronto, Canada) joins Dr Steven Zhao to discuss ultrasound imaging sub-phenotypes in psoriatic arthritis. They discuss clinical vs. imaging clusters of PsA manifestations, the possibility of coagulation and platelet pathway mediation of imaging phenotypes, and more. 

Read the paper here

Thanks for listening to Talking Rheumatology Research! Join the conversation on X using #TalkingRheumResearch, tweet us @RheumJnl, or find us on Instagram and LinkedIn.

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Today's podcast guest is Dr Lucy Carter (Leeds, UK), who joins Dr Chris Wincup to talk about the Easy-BILAG - a comprehensive but simplified version of the BILAG-2004 index for scoring SLE disease activity. They discuss the user-friendly design, training requirements, use with newly approved drugs, and more.

Read the paper here: https://doi.org/10.1093/rheumatology/keab883

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Dr Peter Grayson (NIH, Bethesda, USA) joins Dr Puja Mehta to discuss VEXAS syndrome. They cover the discovery of VEXAS, how to spot the syndrome in patients, the importance of cross-specialty working, and more.

Dr Grayson’s NEJM paper can be found here: https://www.nejm.org/doi/10.1056/NEJMoa2026834

This episode was originally published in May 2021. 

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Prof Christopher Sjöwall (Linköping, Sweden) and Dr Anastastia Madenidou discuss de novo lupus nephritis during treatment with belimumab. They cover the process of collecting observational data, the approval of belimumab for use in lupus nephritis, and implications for clinical practice.

Read the paper here: https://doi.org/10.1093/rheumatology/keaa796

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Dr David Fajgenbaum (University of Pennsylvania, USA) and Dr Puja Mehta discuss cytokine storm syndromes. They consider the definition of cytokine storms and whether COVID-19 meets these criteria, as well as Dr Fajgenbaum’s research journey, as described in his bestselling memoir, 'Chasing my Cure: A Doctor's Race to Turn Hope Into Action'. 

Read the paper here: https://www.nejm.org/doi/full/10.1056/NEJMra2026131

This episode was originally published in March 2021. 

Thanks for listening to Talking Rheumatology Research! Join the conversation on X using #TalkingRheumResearch, tweet us @RheumJnl, or find us on Instagram and LinkedIn.

Want to read more rheumatology research? Explore Rheumatology and Rheumatology Advances in Practice.

Dr Mark Russell (King's College London, UK) joins Dr Sean Gill to talk about improving outcomes for patients hospitalised with gout. They identify several strategies to improve practice and highlight key gaps in the literature that could be addressed by future research.

Read the paper here: https://doi.org/10.1093/rheumatology/keab539

Thanks for listening to Talking Rheumatology Research! Join the conversation on X using #TalkingRheumResearch, tweet us @RheumJnl, or find us on Instagram and LinkedIn.

Want to read more rheumatology research? Explore Rheumatology and Rheumatology Advances in Practice.