Taylor & Francis

In this edition of NCTalks, we’ll be exploring the field of neuroregeneration as part of our latest Spotlight focus on Neuro Central.

The limited capacity for repair in the nervous system represents a significant medical challenge - as the field works to address this, we’re learning more and more about innate regeneration, as well as how the regenerative process can be harnessed and exploited to treat neurodegenerative disease and facilitate repair following injury.

In this podcast, Lauren Pulling (Editor) speaks to Dr Terry Burns, who practices and leads a research group at the Mayo Clinic in Rochester, Minnesota in the USA. His research group is developing regenerative strategies to optimize neurological function and quality of life for patients with brain tumors, neurological injuries and neurodegenerative diseases, with particular research focuses radiation-induced brain injury, microglial biology and cell-based regenerative therapies. Dr Burns tells us about his research, as well as the core challenges in bringing basic regenerative research through to the clinic, and where the field could be heading in the coming years.

You can view more podcasts, plus the latest news and interviews with experts across neurology and neuroscience, at www.neuro-central.com.

In this podcast discover details of the TONIC trial which has yielded promising response rates in patients with metastatic triple-negative breast cancer treated with nivolumab after induction treatment.

Listen to this podcast to discover more about the UNICANCER-NeoPAL study of letrozole and palbociclib in luminal cancer, data from which was presented at this years 2017 ESMO Congress (8–12th September, Madrid, Spain).

You can view more podcasts plus the latest research, news and interviews at www.oncology-central.com

Listen to this podcast to discover more about CheckMate-153 study, data from which was presented at this years 2017 ESMO Congress (8–12th September, Madrid, Spain).

You can view more podcasts plus the latest research, news and interviews at www.oncology-central.com

In this edition of NCTalks, Lauren Pulling (Editor, NC) chats with Rachelle Doody, Global Head of Neurodegeneration at Roche. Rachelle tells us about her varied career so far, moving from academia to industry, and discusses challenges in the neurodegenerative field, as well as the current pipeline treatments and diagnostics at Roche.

You can view more podcasts, plus the latest news and interviews with experts across neurology and neuroscience, at www.neuro-central.com.

At the ESMO World Congress on Gastrointestinal Cancer 2017 (Barcelona, Spain, 28 June–1 July) we had the pleasure of speaking with Vincenzo Valentini from Gemelli ART (Rome, Italy). Listen to the interview now, to find out about the importance of knowledge based oncology and integrating radiotherapy with other treatment modalities such as surgery.

Brain banks are an essential tool for neuropathological studies, allowing us to answer pressing research questions and test new theories. Recent advances in molecular technologies have further expanded the utility of brain banks, while an aging population is increasing interest in dementia and neurodegenerative disorders. But what are the challenges in maintaining, funding and accessing brain banks? How can these be addressed?

Listen our recent panel discussion, held in collaboration with The Drake Foundation, to hear from researchers at Queen Square Brain Bank (London, UK), plus experts from Alzheimer’s Research UK and Alzheimer’s Association, as they discuss the current issues surrounding brain banking.

You can view more podcasts, plus the latest news and interviews with experts across neurology and neuroscience, at www.neuro-central.com.

Whilst at the European Neuro Convention (London, UK, 7–8 June 2017), we caught up with Jean-Pierre Lin, a consultant oediatric neurologist at Guy’s and St Thomas’ NHS Foundation Trust (London, UK), and President of the British Paediatric Neurology Association.

In this NCTalks podcast, Jean-Pierre tells us about his clinical and research work, which focuses on movement disorders and neuromodulation in children. He also expands on current developments in the field of pediatric neurolomodulation, and the challenges that come with treating children with deep brain stimulation.

You can view more podcasts, plus the latest news and interviews with experts across neurology and neuroscience, at www.neuro-central.com.

In this IDHTalks podcast we speak to Mahmoud Ghannoum about the importance of fungi, his work in identifying mycobiome and its implications in health and disease.

At the Alzheimer’s Association International Conference (AAIC; London, UK, 16–20 July 2017), we sat down with Megan Zuelsdorff, University of Wisconsin School of Medicine and Public Health (WI, USA), to hear more about her work on lifetime stress experiences, racial disparities and cognitive health.

Part of the Wisconsin Registry for Alzheimer's Prevention (WRAP) Study, Megan and colleagues examined the impact of lifetime stressful experiences on cognition. They found that a greater number of stressful events was associated with poorer late-life cognitive function for all study participants. In addition, African Americans experienced over 60% more stressful events than non-Hispanic White participants during their lifetimes, and these experiences were linked to poorer memory and thinking skills in older age. The researchers determined that, in African Americans, each stressful experience was equivalent to approximately 4 years of cognitive aging.

In this interview, we hear more about the study and its implications: "Among African Americans in our study, adverse events across the lifespan predict cognitive function more strongly than established risk factors including age, education, and the APOE-e4 Alzheimer's risk gene," Megan said. "Adversity is a clear contributor to racial disparities in cognitive aging, and further study is imperative."

You can view more podcasts, plus the latest news and interviews with experts across neurology and neuroscience, at www.neuro-central.com.