Taylor & Francis

In this MedChemNet podcast, Professor Michelle Arkin (University of California, San Francisco; San Francisco, CA, USA) discusses her work in academic drug discovery and chemical biology and the talk she delivered on the progression of inhibiting protein-protein interactions and utilizing this to potentially re-modulate disease networks to a healthy state.

In this MedChemNet podcast, Dr Gemma Nixon (University of Liverpool, UK) discusses her work in antimalarial, antituberculosis, anti-filariasis and antifungal drug discovery and development and the talk she delivered on the development of the antimalarial E209.

In this podcast Dr Elizabeth Whittaker, Dr James Seddon, Dr Pete Dodd and Professor Beate Kampmann discuss their work in pediatric tuberculosis focusing on the areas of immunology, modelling and drug resistance.

In this edition of NCTalks, we speak to Robyn Klein, a Professor of Medicine, Immunobiology and Neuroscience at Washington University School of Medicine in St Louis, Missouri in the USA. Robyn’s research focuses on the pathogenesis of neuroinflammatory diseases in the CNS, specifically the mechanism of leukocyte recruitment into the CNS, and the direct effects of inflammatory mediators on resident neural cells. In this interview, we ask Robyn about her work in this area as part of our Spotlight on neuroimmunology – we’ll discuss Robyn’s research, how inflammatory processes contribute to neurologic disease, and whether immunology and inflammation could be the basis of an eventual preventative treatment for neurodegenerative diseases such as Alzheimer’s.

You can find more podcasts, articles and news at www.neurology-central.com

Two key themes to come out of the Alzheimer’s Research UK (ARUK) Conference (Aberdeen, UK, 14–15 March 2017) were the celebration of world-class research, and hope for the future of dementia understanding, prevention and treatment, particularly with the forging and strengthening of new partnerships, collaborations and initiatives.

In May 2016, ARUK committed £50 million to support the MRC-led UK Dementia Research Institute (DRI), a new hub of dementia research based at University College London (UK), with additional centers across the UK to be announced imminently. Following an international search, Bart De Strooper was recently announced as the Director of the Institute.

We caught up with Prof De Strooper at the ARUK Conference to find out more about the DRI and his visions for this exciting new venture for dementia research.

You can find more podcasts, interviews and news at www.neurology-central.com

In part 2 of The Changing World of Bioanalysis our panelists discuss what the bioanalytical lab of the future might look like.

Discussions included:

The need for bioanalysts to acquire more biological skills in order to understand newer generation of complex molecules.

Convergence of different units of companies and merging of skills.

The role of automation in the bioanalytical lab of the future.

In part 1 of this 3-part video filmed at Barcelona our panel of experts discuss the issue of skills gap in the bioanalytical laboratory and the changing nature of the relationship between Pharma and CROs as outsourcing continues to increase.

Discussions include:

- Decreasing current skills gap evident in most bioanalytical labs, particularly in younger generation of bioanalysts.

- Collaborations between industry and academia to produce a newer generation of bioanalysts better able to deal with more challenging bioanalytical problems.

- Training both new and existing staff to deal with more challenging bioanalytical problems (more challenging molecules and newer constructs) and cross training staff within organisations.

- The changing nature of the CRO-Pharma relationship.

In this RegMedNet podcast, Mike Rice explains the make or break impact of biopreservation in the potential commercialization of cell therapies.

Our RegMedNet Podcast talks to Dr Aric Rogers about how he is studying factors such as genetic variations and environmental conditions that can influence life span using roundworms. Dr Rogers provides his thoughts and predictions on how dietary restriction for therapeutic benefits could be adopted for the future.

Our RegmedNet Podcast talks to Dr Sandra Rieger about how the Rieger lab uses zebrafish as a model to study wound healing mechanisms and nerve regeneration in peripheral neuropathy. Dr Sandra Rieger provides her thoughts and opinions on the future of zebrafish in research, and future regenerative medicine therapies.